Ugt1a6 Gene Search Result

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12 records found for search term Ugt1a6

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1349499	UGT1A6	UDP glucuronosyltransferase family 1 member A6	This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronos ... (more) yltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq, Jul 2008]	2	233691702	233773300	Human	450	symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
12077464	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6	ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN 4-chlorobiphenyl metabolic process (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular re ... (more) sponse to hormone stimulus (ortholog); PARTICIPATES IN paracetamol pharmacokinetics pathway; phenytoin pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); contact dermatitis (ortholog); Crigler-Najjar syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog); protein-containing complex (ortholog); INTERACTS WITH paracetamol	25	45081655	45161584	Dog	42	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155244865	ugt1a6						Tropical Clawed Frog		symbol	gene, null
626158376	Ugt1a6	UDP glucuronosyltransferase family 1 member A6	ENCODES a protein that exhibits enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN 4-chlorobiphenyl metabolic process (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to hormone sti ... (more) mulus (ortholog); PARTICIPATES IN paracetamol pharmacokinetics pathway; phenytoin pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); contact dermatitis (ortholog); Crigler-Najjar syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog); protein-containing complex (ortholog)				Black Rat	28	symbol	gene, protein-coding, MODEL [RefSeq]
14040540	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6	ENCODES a protein that exhibits enzyme binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN bile acid secretion (ortholog); estrogen metabolic process (ortholog); flavonoid metabolic process (ortholog); PARTICIPATES IN codeine ... (more) and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ASSOCIATED WITH Crigler-Najjar syndrome (ortholog); Gilbert syndrome (ortholog); schizophrenia (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH deoxynivalenol				Pig	34	symbol , old_gene_symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155244864	ugt1a6.S						African Clawed Frog		symbol	gene, null
18902903	LOC101707823	UDP-glucuronosyltransferase 1-6	ENCODES a protein that exhibits glucuronosyltransferase activity (inferred); glycosyltransferase activity (inferred); transferase activity (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred)				Naked Mole-Rat	8	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
8841343	LOC102006309	UDP-glucuronosyltransferase 1-8		NW_004955453	2386649	2547914	Chinchilla		old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
1583689	Ugt1a5	UDP glucuronosyltransferase family 1 member A5	ENCODES a protein that exhibits enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cellular response to ethanol; cellular response to glucocorticoid stimulus; cellular response to hormone stimulus; PARTICIPATES IN nicot ... (more) ine pharmacodynamics pathway; nicotine pharmacokinetics pathway; phenytoin pharmacodynamics pathway; ASSOCIATED WITH celiac disease (ortholog); Crigler-Najjar syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (-)-cotinine (ortholog); (5Z,8Z,11Z,13E)-15-HETE (ortholog); (S)-nicotine (ortholog)	9	96210053	96256264	Rat	175	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
620949	Ugt1a6a	UDP glucuronosyltransferase family 1 member A6a	ENCODES a protein that exhibits protein-containing complex binding; enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); INVOLVED IN 4-chlorobiphenyl metabolic process; cellular response to glucocorticoid stimulus; cellular response to hormone stimulus; PARTICIPATES IN paracetamol ... (more) pharmacokinetics pathway; phenytoin pharmacodynamics pathway; ascorbate and aldarate metabolic pathway; ASSOCIATED WITH type 2 diabetes mellitus; autism spectrum disorder (ortholog); contact dermatitis (ortholog); FOUND IN protein-containing complex; endoplasmic reticulum (ortholog); INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene; 1,7-phenanthroline; 1-naphthol	9	96195018	96256264	Rat	437	symbol , PhenoGen , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1550326	Ugt1a6a	UDP glucuronosyltransferase 1 family, polypeptide A6A	Enables alpha-glucuronidase activity and glucuronosyltransferase activity. Involved in L-ascorbic acid biosynthetic process. Acts upstream of or within glucuronate metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; integumenta ... (more) l system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human UGT1A6 (UDP glucuronosyltransferase family 1 member A6). [provided by Alliance of Genome Resources, Jul 2025]	1	88062531	88147724	Mouse	247	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1619652	Ugt1a6b	UDP glucuronosyltransferase 1 family, polypeptide A6B	Predicted to enable enzyme binding activity; glucuronosyltransferase activity; and protein dimerization activity. Predicted to be involved in 4-chlorobiphenyl metabolic process and cellular response to glucocorticoid stimulus. Predicted to be located in intracellular membrane-bounded organelle. Pred ... (more) icted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human UGT1A6 (UDP glucuronosyltransferase family 1 member A6). [provided by Alliance of Genome Resources, Apr 2025]	1	88030979	88146720	Mouse	279	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]