UGT1A6 (UDP glucuronosyltransferase 1 family, polypeptide A6) - Rat Genome Database

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Gene: UGT1A6 (UDP glucuronosyltransferase 1 family, polypeptide A6) Sus scrofa
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Symbol: UGT1A6
Name: UDP glucuronosyltransferase 1 family, polypeptide A6
RGD ID: 14040540
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); retinoic acid binding (ortholog); INVOLVED IN bile acid secretion (ortholog); estrogen metabolic process (ortholog); vitamin D3 metabolic process (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ASSOCIATED WITH bilirubin metabolic disorder (ortholog); Crigler Najjar Syndrome, Type 2 (ortholog); Crigler-Najjar syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: mpugt1A6; UDP-glucuronosyltransferase 1-6 pseudogene; UDP-glucuronosyltransferase 1A1; UDP-glucuronosyltransferase 1A6
RGD Orthologs
Human
Mouse
Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115133,968,693 - 134,049,029 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215148,087,506 - 148,164,555 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:23449330   PMID:26134041  


Genomics

Comparative Map Data
UGT1A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115133,968,693 - 134,049,029 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215148,087,506 - 148,164,555 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UGT1A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,729,042 - 233,773,300 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2233,729,042 - 233,773,300 (+)EnsemblGRCh38hg38GRCh38
GRCh372234,637,688 - 234,681,946 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362234,302,512 - 234,346,684 (+)NCBINCBI36hg18NCBI36
Build 342234,419,772 - 234,463,945NCBI
Celera2228,358,392 - 228,402,577 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2226,437,616 - 226,481,779 (+)NCBIHuRef
CHM1_12234,643,587 - 234,682,899 (+)NCBICHM1_1
T2T-CHM13v2.02234,217,673 - 234,261,929 (+)NCBI
Ugt1a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39188,128,333 - 88,147,724 (+)NCBIGRCm39mm39
GRCm39 Ensembl188,128,323 - 88,146,719 (+)Ensembl
GRCm38188,200,611 - 88,220,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl188,200,601 - 88,218,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv37190,097,186 - 90,116,577 (+)NCBIGRCm37mm9NCBIm37
MGSCv36190,031,782 - 90,050,168 (+)NCBImm8
Celera191,161,681 - 91,181,062 (+)NCBICelera
Cytogenetic Map1DNCBI
Ugt1a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2988,780,328 - 88,808,465 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl988,713,184 - 88,808,465 (+)Ensembl
Rnor_6.0995,274,707 - 95,302,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl995,161,157 - 95,302,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,961,922 - 94,990,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4987,070,247 - 87,098,362 (+)NCBIRGSC3.4rn4RGSC3.4
Celera986,341,626 - 86,369,556 (+)NCBICelera
Cytogenetic Map9q35NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 1
Low 2 1 3 1 1 2 1
Below cutoff 2 2 2 2 1 9

Sequence


Reference Sequences
RefSeq Acc Id: NM_001278750   ⟹   NP_001265679
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115134,033,779 - 134,048,407 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005672293   ⟹   XP_005672350
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115134,018,960 - 134,049,029 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005672294   ⟹   XP_005672351
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,980,616 - 134,049,027 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013984599   ⟹   XP_013840053
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,968,693 - 134,049,027 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013984602   ⟹   XP_013840056
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115134,018,970 - 134,049,029 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_013840053   ⟸   XM_013984599
- Peptide Label: isoform X3
- UniProtKB: F1SM21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672351   ⟸   XM_005672294
- Peptide Label: isoform X2
- UniProtKB: A0A287B177 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672350   ⟸   XM_005672293
- Peptide Label: isoform X1
- UniProtKB: F1SM17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013840056   ⟸   XM_013984602
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001265679   ⟸   NM_001278750
- Peptide Label: precursor
- UniProtKB: F1SM20 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
UDPGT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000036274 UniProtKB/TrEMBL
  ENSSSCG00015060507 UniProtKB/TrEMBL
  ENSSSCG00025070666 UniProtKB/TrEMBL
  ENSSSCG00030031937 UniProtKB/TrEMBL
  ENSSSCG00035014372 UniProtKB/TrEMBL
  ENSSSCG00040071161 UniProtKB/TrEMBL
  ENSSSCG00060071575 UniProtKB/TrEMBL
  ENSSSCG00065072695 UniProtKB/TrEMBL
  ENSSSCG00070008473 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000017273 UniProtKB/TrEMBL
  ENSSSCP00000017281 UniProtKB/TrEMBL
  ENSSSCP00000017284 UniProtKB/TrEMBL
  ENSSSCP00000049914 UniProtKB/TrEMBL
  ENSSSCP00015032795 UniProtKB/TrEMBL
  ENSSSCP00015032863 UniProtKB/TrEMBL
  ENSSSCP00025042609 UniProtKB/TrEMBL
  ENSSSCP00025042663 UniProtKB/TrEMBL
  ENSSSCP00030020017 UniProtKB/TrEMBL
  ENSSSCP00030020030 UniProtKB/TrEMBL
  ENSSSCP00035006341 UniProtKB/TrEMBL
  ENSSSCP00035006344 UniProtKB/TrEMBL
  ENSSSCP00040043610 UniProtKB/TrEMBL
  ENSSSCP00040043667 UniProtKB/TrEMBL
  ENSSSCP00060042382 UniProtKB/TrEMBL
  ENSSSCP00060042402 UniProtKB/TrEMBL
  ENSSSCP00065043921 UniProtKB/TrEMBL
  ENSSSCP00070013563 UniProtKB/TrEMBL
  ENSSSCP00070013566 UniProtKB/TrEMBL
  ENSSSCP00070013574 UniProtKB/TrEMBL
  ENSSSCP00070013582 UniProtKB/TrEMBL
  ENSSSCP00070013586 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017754 UniProtKB/TrEMBL
  ENSSSCT00000017762 UniProtKB/TrEMBL
  ENSSSCT00000017765 UniProtKB/TrEMBL
  ENSSSCT00000047497 UniProtKB/TrEMBL
  ENSSSCT00015081066 UniProtKB/TrEMBL
  ENSSSCT00015081237 UniProtKB/TrEMBL
  ENSSSCT00025097052 UniProtKB/TrEMBL
  ENSSSCT00025097173 UniProtKB/TrEMBL
  ENSSSCT00030044483 UniProtKB/TrEMBL
  ENSSSCT00030044513 UniProtKB/TrEMBL
  ENSSSCT00035018204 UniProtKB/TrEMBL
  ENSSSCT00035018209 UniProtKB/TrEMBL
  ENSSSCT00040097771 UniProtKB/TrEMBL
  ENSSSCT00040097863 UniProtKB/TrEMBL
  ENSSSCT00060097771 UniProtKB/TrEMBL
  ENSSSCT00060097811 UniProtKB/TrEMBL
  ENSSSCT00065100001 UniProtKB/TrEMBL
  ENSSSCT00070016381 UniProtKB/TrEMBL
  ENSSSCT00070016385 UniProtKB/TrEMBL
  ENSSSCT00070016397 UniProtKB/TrEMBL
  ENSSSCT00070016408 UniProtKB/TrEMBL
  ENSSSCT00070016412 UniProtKB/TrEMBL
InterPro UDP_glucos_trans UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/TrEMBL
KEGG Report ssc:100152603 UniProtKB/TrEMBL
NCBI Gene UGT1A6 ENTREZGENE
Pfam UDPGT UniProtKB/TrEMBL
PROSITE UDPGT UniProtKB/TrEMBL
UniProt A0A287B177 ENTREZGENE, UniProtKB/TrEMBL
  A0A481D317_PIG UniProtKB/TrEMBL
  A0A4X1TBK7_PIG UniProtKB/TrEMBL
  A0A4X1TBM1_PIG UniProtKB/TrEMBL
  A0A4X1TDB2_PIG UniProtKB/TrEMBL
  A0A4X1TDD0_PIG UniProtKB/TrEMBL
  A0A4X1TFL0_PIG UniProtKB/TrEMBL
  F1SM17 ENTREZGENE, UniProtKB/TrEMBL
  F1SM20 ENTREZGENE, UniProtKB/TrEMBL
  F1SM21 ENTREZGENE
  F1SM28_PIG UniProtKB/TrEMBL
UniProt Secondary M1VEG8 UniProtKB/TrEMBL