Uchl1 Gene Search Result

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18 records found for search term Uchl1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
3928	Uchl1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); INVOLVED IN ubiquitin-dependent protein catabolic process; adult walking behavior (ortholog); axon target recognition (o ... (more) rtholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH retinal disease; Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol	14	41838859	41849743	Rat	324	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
733510	UCHL1	ubiquitin C-terminal hydrolase L1	The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene ma ... (more) y be associated with Parkinson disease.[provided by RefSeq, Sep 2009]	4	41256928	41268455	Human	421	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
736277	Uchl1	ubiquitin carboxy-terminal hydrolase L1	Enables cysteine-type deubiquitinase activity; ribosome binding activity; and ubiquitin binding activity. Involved in cellular response to xenobiotic stimulus. Acts upstream of or within several processes, including adult walking behavior; axon target recognition; and male germ cell proliferation. L ... (more) ocated in several cellular components, including axon; neuron projection terminus; and neuronal cell body. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; hereditary spastic paraplegia 79A; and hereditary spastic paraplegia 79B. Orthologous to human UCHL1 (ubiquitin C-terminal hydrolase L1). [provided by Alliance of Genome Resources, Jul 2025]	5	66833464	66844577	Mouse	400	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8799930	Uchl1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (or ... (more) tholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytosol (ortholog)	NW_004955443	6367519	6379638	Chinchilla	63	symbol	gene, protein-coding, MODEL [RefSeq]
12040055	UCHL1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type endopeptidase activity (ortholog); omega peptidase activity (ortholog); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (ortholog); ASSO ... (more) CIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN nucleoplasm (ortholog); plasma membrane (ortholog)	4	35580755	35592314	Bonobo	71	symbol	gene, protein-coding, MODEL [RefSeq]
12107329	UCHL1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type endopeptidase activity (ortholog); omega peptidase activity (ortholog); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (ortholog); ASSO ... (more) CIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (ortholog); cytosol (ortholog); neuron projection terminus (ortholog)	3	71396694	71430395	Dog	73	symbol	gene, protein-coding, MODEL [RefSeq]
12556021	Uchl1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (inferred); cysteine-type deubiquitinase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (or ... (more) tholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (inferred); cytoplasm (inferred); cytosol (inferred)	NW_004936482	8551749	8563586	Squirrel	72	symbol	gene, protein-coding, MODEL [RefSeq]
18919326	Uchl1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type endopeptidase activity (ortholog); omega peptidase activity (ortholog); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (ortholog); ASSO ... (more) CIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (ortholog); cytosol (ortholog); neuron projection terminus (ortholog)				Naked Mole-Rat	71	symbol	gene, protein-coding, MODEL [RefSeq]
155250831	uchl1						Tropical Clawed Frog		symbol	gene, null
18727027	UCHL1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (inferred); cysteine-type deubiquitinase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (or ... (more) tholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (inferred); cytoplasm (inferred); cytosol (inferred)				Green Monkey	72	symbol	gene, protein-coding, MODEL [RefSeq]
625905795	Uchl1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (or ... (more) tholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytosol (ortholog)				Black Rat	63	symbol	gene, protein-coding, MODEL [RefSeq]
14032459	UCHL1	ubiquitin C-terminal hydrolase L1	ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (inferred); cysteine-type deubiquitinase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (or ... (more) tholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (inferred); cytoplasm (inferred); cytosol (inferred)				Pig	72	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155244660	uchl1.L						African Clawed Frog		symbol	gene, null
155251103	uchl1.S						African Clawed Frog		symbol	gene, null
7243017	UCHL1-DT	UCHL1 divergent transcript	INTERACTS WITH aflatoxin B1	4	41220074	41256727	Human	1	symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
16560227	AP002512.1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1) pseudogene		11	56495761	56496413	Human		name	gene, pseudo, INFERRED [RefSeq]
16560360	AP002512.2	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1) pseudogene		11	56509574	56510196	Human		name	gene, pseudo, INFERRED [RefSeq]
7207192	Uchl1os	ubiquitin carboxy-terminal hydrolase L1, opposite strand	Involved in cellular response to xenobiotic stimulus. Acts upstream of or within with a positive effect on translation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]	5	66783838	66833840	Mouse		symbol , PhenoGen , old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]