| 621562 | Ubb | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); neuron projection (ortholog); neuronal cell body (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride | 10 | 47746923 | 47748628 | Rat | 152 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1344008 | UBB | ubiquitin B | This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] | 17 | 16380779 | 16382745 | Human | 206 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552783 | Ubb | ubiquitin B | This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of four direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Pseudogenes of this gene are located on chromosomes 3 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | 11 | 62442329 | 62444037 | Mouse | 194 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11817219 | UBB | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); neuron projection (ortholog); neuronal cell body (ortholog) | 17 | 35286699 | 35288429 | Bonobo | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12054946 | UBB | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred); neuron projection (inferred) | 5 | 39533365 | 39535120 | Dog | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12451545 | Ubb | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); neuron projection (ortholog); neuronal cell body (ortholog) | NW_004936821 | 241981 | 243304 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13927580 | UBB | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred); neuron projection (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 52 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18485634 | UBB | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); neuron projection (ortholog); neuronal cell body (ortholog) | | | | Green Monkey | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900853 | Ubb | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); neuron projection (ortholog); neuronal cell body (ortholog) | | | | Naked Mole-Rat | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284496401 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 596933970 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 596934186 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 596934409 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 596934616 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 596934908 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 596935163 | ubb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 284713128 | ubb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284183161 | ubb.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1613210 | Ubb-ps | ubiquitin B, pseudogene | INTERACTS WITH (1->4)-beta-D-glucan; 2,3',4,4',5-Pentachlorobiphenyl; bisphenol A | 14 | 46321484 | 46322414 | Mouse | 4 | symbol , PhenoGen | gene, pseudo, VALIDATED [RefSeq] |
| 616940609 | UBB-AS1 | UBB antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |
| 6496493 | Ubb-ps1 | ubiquitin B, pseudogene 1 | FOUND IN cytoplasm (inferred); nucleus (inferred) | 5 | 137889936 | 137890385 | Rat | 2 | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 736389 | Rps27a | ribosomal protein S27A | Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process; protein ubiquitination; and ribosomal small subunit biogenesis. Located in myeli n sheath. Is active in synapse. Orthologous to human RPS27A (ribosomal protein S27a). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 29495842 | 29498040 | Mouse | 172 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620240 | Rps27a-ps1 | ribosomal protein S27a, pseudogene 1 | FOUND IN cytosolic small ribosomal subunit; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 5 | 138465502 | 138466080 | Rat | 3 | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 68344 | Uba52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN response to insecticide; cytoplasmic translation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Brain Injuries; colon carcinoma (ortholog); Diabetic Nephropathies (ortholog); FOUND IN cytosolic large ribosomal subunit; cytoplasm (ortholog); cytoplasmic side of rough endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione | 16 | 18952583 | 18954780 | Rat | 146 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 68483 | Uba52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | A structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in optic vesicle. Orthologous to human UBA52 (ubiquitin A -52 residue ribosomal protein fusion product 1). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 70960913 | 70963067 | Mouse | 162 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1624057 | Ubc | ubiquitin C | Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Located in myelin sheath. Is expressed in inner ear; jugular lymph sac; oocyte; telencephalon; and trunk un segmented mesenchyme. Orthologous to human UBC (ubiquitin C). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 125463029 | 125467081 | Mouse | 229 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2322951 | Ubbl1 | ubiquitin B like 1 | | 14 | 34667025 | 34667344 | Rat | 6 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 2321712 | Ubbl2 | ubiquitin B like 2 | | 10 | 48409685 | 48409930 | Rat | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 41131560 | Ubbl3 | ubiquitin B like 3 | | 9 | 28157830 | 28158872 | Rat | | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1347287 | UBBP1 | ubiquitin B pseudogene 1 | | 2 | 136329300 | 136330012 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1352261 | UBBP2 | ubiquitin B pseudogene 2 | INTERACTS WITH bisphenol A; silicon dioxide | 1 | 217850259 | 217850731 | Human | 2 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1349521 | UBBP3 | ubiquitin B pseudogene 3 | | 2 | 148863427 | 148863834 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1346838 | UBBP4 | ubiquitin B pseudogene 4 | INTERACTS WITH acrylamide; testosterone; bisphenol A (ortholog) | 17 | 22090750 | 22205151 | Human | 3 | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 6481543 | UBBP5 | ubiquitin B pseudogene 5 | | 13 | 87219004 | 87219417 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1564290 | Rps27a-ps12 | ribosomal protein S27a, pseudogene 12 | ENCODES a pseudogene that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN cytosol (inferred); ribonucleoprotein complex (inferred); ribosome (inferred); INTERACTS WITH bisphenol A; acrylamide (ortholog); testosterone (ortholog) | 18 | 24517016 | 24517709 | Rat | 15 | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1605374 | UBA6 | ubiquitin like modifier activating enzyme 6 | Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzym e that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008] | 4 | 67612652 | 67701155 | Human | 100 | description | gene, protein-coding, VALIDATED [RefSeq] |