UBB (ubiquitin B) - Rat Genome Database

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Gene: UBB (ubiquitin B) Canis lupus familiaris
Analyze
Symbol: UBB
Name: ubiquitin B
RGD ID: 12054946
Description: ENCODES a protein that exhibits protein tag activity (inferred); RNA binding (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); intracellular organelle (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polyubiquitin-B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,533,365 - 39,535,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,511,426 - 39,535,815 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha539,679,659 - 39,681,890 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0539,643,511 - 39,645,744 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,640,787 - 39,645,440 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,615,228 - 39,617,465 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,560,488 - 39,562,718 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0539,752,689 - 39,754,922 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202   PMID:37756605  


Genomics

Comparative Map Data
UBB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,533,365 - 39,535,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,511,426 - 39,535,815 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha539,679,659 - 39,681,890 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0539,643,511 - 39,645,744 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,640,787 - 39,645,440 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,615,228 - 39,617,465 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,560,488 - 39,562,718 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0539,752,689 - 39,754,922 (-)NCBIUU_Cfam_GSD_1.0
UBB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381716,380,779 - 16,382,745 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1716,380,798 - 16,382,745 (+)EnsemblGRCh38hg38GRCh38
GRCh371716,284,093 - 16,286,059 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361716,225,092 - 16,226,779 (+)NCBINCBI36Build 36hg18NCBI36
Build 341716,225,091 - 16,226,779NCBI
Celera1716,187,292 - 16,188,979 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1716,150,949 - 16,152,636 (+)NCBIHuRef
CHM1_11716,294,106 - 16,295,793 (+)NCBICHM1_1
T2T-CHM13v2.01716,283,097 - 16,285,063 (+)NCBIT2T-CHM13v2.0
Ubb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,442,329 - 62,444,037 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,441,997 - 62,444,039 (+)EnsemblGRCm39 Ensembl
GRCm381162,551,171 - 62,553,213 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,551,171 - 62,553,213 (+)EnsemblGRCm38mm10GRCm38
MGSCv371162,365,006 - 62,366,714 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,367,697 - 62,369,407 (+)NCBIMGSCv36mm8
Celera1169,470,925 - 69,472,633 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1138.46NCBI
Ubb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,746,923 - 47,748,628 (+)NCBIGRCr8
mRatBN7.21047,247,630 - 47,249,335 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1047,245,637 - 47,249,333 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1051,951,219 - 51,952,925 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,441,764 - 51,443,470 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,945,175 - 46,946,881 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,880,231 - 48,881,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,881,049 - 48,881,881 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01048,664,227 - 48,665,056 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11048,752,613 - 48,753,069NCBI
Celera1046,494,897 - 46,496,578 (+)NCBICelera
Cytogenetic Map10q23NCBI
UBB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21956,252,196 - 56,254,227 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11761,063,907 - 61,065,938 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01735,286,699 - 35,288,429 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A110,578,715 - 110,580,217 (+)NCBIpanpan1.1PanPan1.1panPan2
Ubb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560259,569,737 - 59,571,169 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936821241,981 - 243,304 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,171,289 - 59,172,841 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,171,258 - 59,172,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21262,297,981 - 62,299,561 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11615,279,271 - 15,289,111 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660595,683,854 - 5,685,836 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248774,050,188 - 4,051,768 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248774,050,188 - 4,051,849 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UBB
66 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 3 13 1 3 11 8 10
Medium 2 5 9 6 5 6 3 6 1 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000036025   ⟹   ENSCAFP00000031353
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl539,533,662 - 39,534,226 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000085130   ⟹   ENSCAFP00000063279
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl539,511,426 - 39,534,226 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000086783   ⟹   ENSCAFP00000048830
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl539,533,749 - 39,535,815 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845007874   ⟹   ENSCAFP00845006223
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl539,640,787 - 39,645,440 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845007878   ⟹   ENSCAFP00845006226
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl539,643,519 - 39,645,177 (-)Ensembl
RefSeq Acc Id: XM_014113619   ⟹   XP_013969094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1539,533,365 - 39,535,120 (-)NCBI
Dog10K_Boxer_Tasha539,679,659 - 39,681,890 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022418619   ⟹   XP_022274327
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1539,533,365 - 39,534,794 (-)NCBI
Dog10K_Boxer_Tasha539,679,659 - 39,681,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038475814   ⟹   XP_038331742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1539,615,228 - 39,617,465 (-)NCBI
RefSeq Acc Id: XM_038475815   ⟹   XP_038331743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1539,615,228 - 39,616,927 (-)NCBI
RefSeq Acc Id: XM_038536997   ⟹   XP_038392925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0539,752,689 - 39,754,922 (-)NCBI
RefSeq Acc Id: XM_038536998   ⟹   XP_038392926
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0539,752,689 - 39,754,385 (-)NCBI
RefSeq Acc Id: XM_038601137   ⟹   XP_038457065
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0539,560,488 - 39,562,718 (-)NCBI
RefSeq Acc Id: XM_038601138   ⟹   XP_038457066
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0539,560,488 - 39,562,180 (-)NCBI
RefSeq Acc Id: XM_038665709   ⟹   XP_038521637
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0539,643,511 - 39,645,744 (-)NCBI
RefSeq Acc Id: XM_038665710   ⟹   XP_038521638
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0539,643,511 - 39,645,207 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013969094   ⟸   XM_014113619
- UniProtKB: A0A8I3MMN5 (UniProtKB/TrEMBL),   A0A8P0PPZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022274327   ⟸   XM_022418619
- UniProtKB: A0A8I3MMN5 (UniProtKB/TrEMBL),   A0A8P0PPZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000048830   ⟸   ENSCAFT00000086783
RefSeq Acc Id: ENSCAFP00000063279   ⟸   ENSCAFT00000085130
RefSeq Acc Id: ENSCAFP00000031353   ⟸   ENSCAFT00000036025
RefSeq Acc Id: XP_038331742   ⟸   XM_038475814
RefSeq Acc Id: XP_038331743   ⟸   XM_038475815
RefSeq Acc Id: XP_038457065   ⟸   XM_038601137
RefSeq Acc Id: XP_038457066   ⟸   XM_038601138
RefSeq Acc Id: XP_038521637   ⟸   XM_038665709
- UniProtKB: A0A8I3MMN5 (UniProtKB/TrEMBL),   A0A8P0PPZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038521638   ⟸   XM_038665710
- UniProtKB: A0A8I3MMN5 (UniProtKB/TrEMBL),   A0A8P0PPZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392925   ⟸   XM_038536997
- UniProtKB: A0A8I3MMN5 (UniProtKB/TrEMBL),   A0A8P0PPZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392926   ⟸   XM_038536998
- UniProtKB: A0A8I3MMN5 (UniProtKB/TrEMBL),   A0A8P0PPZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845006223   ⟸   ENSCAFT00845007874
RefSeq Acc Id: ENSCAFP00845006226   ⟸   ENSCAFT00845007878
Protein Domains
Ubiquitin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023443 Ensembl
  ENSCAFG00000058642 UniProtKB/TrEMBL
  ENSCAFG00845004386 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000085130.2 UniProtKB/TrEMBL
  ENSCAFT00000105143.1 UniProtKB/TrEMBL
  ENSCAFT00845007874 ENTREZGENE
  ENSCAFT00845007874.1 UniProtKB/TrEMBL
  ENSCAFT00845007878 ENTREZGENE
  ENSCAFT00845007878.1 UniProtKB/TrEMBL
InterPro Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  Ubiquitin_CS UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/TrEMBL
NCBI Gene UBB ENTREZGENE
PANTHER UBIQUITIN UniProtKB/TrEMBL
  UBIQUITIN-60S RIBOSOMAL PROTEIN L40 UniProtKB/TrEMBL
Pfam ubiquitin UniProtKB/TrEMBL
PRINTS UBIQUITIN UniProtKB/TrEMBL
PROSITE UBIQUITIN_1 UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/TrEMBL
SMART UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A8I3MMN5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PPZ3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49664 ENTREZGENE