| 620927 | Slc27a1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits biotin transmembrane transporter activity (ortholog); efflux transmembrane transporter activity (ortholog); fatty acid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); biotin import across plasma membrane ( ortholog); biotin transport (ortholog); PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; ASSOCIATED WITH familial hyperlipidemia; glucose intolerance; hyperinsulinism; FOUND IN caveola; mitochondrial inner membrane; basal plasma membrane (ortholog); INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2-Ethylhexanoic acid | 16 | 18311859 | 18337024 | Rat | 271 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1553168 | Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | Enables several functions, including fatty acid-CoA ligase activity; icosanoid transmembrane transporter activity; and protein serine/threonine kinase activator activity. Involved in glucose import in response to insulin stimulus; long-chain fatty acid import into cell; and positive regulation of tr iglyceride biosynthetic process. Acts upstream of or within several processes, including adiponectin-activated signaling pathway; fatty acid transport; and response to insulin. Located in basal plasma membrane and endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; phalanx; and sensory organ. Orthologous to human SLC27A1 (solute carrier family 27 member 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 72021372 | 72039951 | Mouse | 274 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604940 | SLC27A1 | solute carrier family 27 member 1 | Enables biotin transmembrane transporter activity; efflux transmembrane transporter activity; and long-chain fatty acid transmembrane transporter activity. Involved in export across plasma membrane; lipid transport across blood-brain barrier; and monocarboxylic acid transport. Located in plasma memb rane. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 17468767 | 17506168 | Human | 264 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8897578 | Slc27a1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits biotin transmembrane transporter activity (ortholog); efflux transmembrane transporter activity (ortholog); fatty acid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); biotin import across plasma membrane ( ortholog); biotin transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intolerance (ortholog); hyperinsulinism (ortholog); FOUND IN basal plasma membrane (ortholog); caveola (ortholog); endoplasmic reticulum (ortholog) | NW_004955524 | 803793 | 821920 | Chinchilla | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11751878 | SLC27A1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits icosanoid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); fatty acid transport (ortholog); long-chain fatty acid transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intoleranc e (ortholog); hyperinsulinism (ortholog); FOUND IN caveola (ortholog) | 19 | 16956000 | 16993429 | Bonobo | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12282759 | SLC27A1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits icosanoid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); fatty acid transport (ortholog); long-chain fatty acid transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intoleranc e (ortholog); hyperinsulinism (ortholog); FOUND IN caveola (ortholog); mitochondrial inner membrane (ortholog) | 20 | 45309094 | 45341101 | Dog | 62 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12615645 | Slc27a1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits icosanoid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); fatty acid transport (ortholog); long-chain fatty acid transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intoleranc e (ortholog); hyperinsulinism (ortholog); FOUND IN caveola (ortholog) | NW_004936596 | 3426807 | 3451259 | Squirrel | 60 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18910164 | Slc27a1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits biotin transmembrane transporter activity (ortholog); efflux transmembrane transporter activity (ortholog); icosanoid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); biotin import across plasma membrane (o rtholog); biotin transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intolerance (ortholog); hyperinsulinism (ortholog); FOUND IN basal plasma membrane (ortholog); caveola (ortholog); endoplasmic reticulum (ortholog) | | | | Naked Mole-Rat | 63 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866142 | SLC27A1 | solute carrier family 27 member 1 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 14254356 | SLC27A1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits icosanoid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); fatty acid transport (ortholog); long-chain fatty acid transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intoleranc e (ortholog); hyperinsulinism (ortholog); FOUND IN caveola (ortholog); mitochondrial inner membrane (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 63 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18636543 | SLC27A1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits icosanoid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); fatty acid transport (ortholog); long-chain fatty acid transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intoleranc e (ortholog); hyperinsulinism (ortholog); FOUND IN caveola (ortholog) | | | | Green Monkey | 61 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626145589 | Slc27a1 | solute carrier family 27 member 1 | ENCODES a protein that exhibits biotin transmembrane transporter activity (ortholog); efflux transmembrane transporter activity (ortholog); fatty acid transmembrane transporter activity (ortholog); INVOLVED IN adiponectin-activated signaling pathway (ortholog); biotin import across plasma membrane ( ortholog); biotin transport (ortholog); ASSOCIATED WITH familial hyperlipidemia (ortholog); glucose intolerance (ortholog); hyperinsulinism (ortholog); FOUND IN basal plasma membrane (ortholog); caveola (ortholog); endoplasmic reticulum (ortholog) | | | | Black Rat | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |