| 3534 | Rara | retinoic acid receptor, alpha | ENCODES a protein that exhibits heterocyclic compound binding; histone deacetylase binding; mRNA 5'-UTR binding; INVOLVED IN female pregnancy; hippocampus development; liver development; PARTICIPATES IN retinoic acid signaling pathway; acute myeloid leukemia pathway; ASSOCIATED WITH amyotrophic late ral sclerosis; Spinal Cord Injuries; acute promyelocytic leukemia (ortholog); FOUND IN dendrite; perinuclear region of cytoplasm; chromatin (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 84379780 | 84424371 | Rat | 543 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 11216 | Rara | retinoic acid receptor, alpha | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and transcription coactivator binding activity. Involved in several processes, including Sertoli cell fate commitment; cellular response to lipopolysaccharide; and germ cell d evelopment. Acts upstream of or within several processes, including cartilage development; negative regulation of cartilage development; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human RARA (retinoic acid receptor alpha). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 98818626 | 98865768 | Mouse | 846 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 733999 | RARA | retinoic acid receptor alpha | This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Tr anslocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010] | 17 | 40309180 | 40357643 | Human | 562 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 9007799 | Rara | retinoic acid receptor alpha | ENCODES a protein that exhibits alpha-actinin binding (ortholog); chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN apoptotic cell clearance (ortholog); bone development (ortholog); cellular response to estrogen stimulus (ortholog); PARTICIPATES IN retinoic acid signaling p athway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955451 | 14876663 | 14917134 | Chinchilla | 182 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11944369 | RARA | retinoic acid receptor alpha | ENCODES a protein that exhibits alpha-actinin binding (ortholog); chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN apoptotic cell clearance (ortholog); bone development (ortholog); cellular response to estrogen stimulus (ortholog); PARTICIPATES IN retinoic acid signaling p athway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog) | 17 | 16932485 | 16980958 | Bonobo | 186 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12271777 | RARA | retinoic acid receptor alpha | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); histone deacetylase binding (ortholog); mRNA 5'-UTR binding (ortholog); INVOLVED IN bone development (ortholog); chondroblast differentiation (ortholog); embryonic camera-type eye development (ortholog); PARTICIPATES IN retino ic acid signaling pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | 9 | 22254803 | 22298614 | Dog | 195 | symbol , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12732369 | Rara | retinoic acid receptor alpha | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); histone deacetylase binding (ortholog); mRNA 5'-UTR binding (ortholog); INVOLVED IN bone development (ortholog); chondroblast differentiation (ortholog); embryonic camera-type eye development (ortholog); PARTICIPATES IN retino ic acid signaling pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | NW_004936490 | 15376217 | 15420638 | Squirrel | 198 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14187422 | RARA | retinoic acid receptor alpha | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); histone deacetylase binding (ortholog); mRNA 5'-UTR binding (ortholog); INVOLVED IN bone development (ortholog); chondroblast differentiation (ortholog); embryonic camera-type eye development (ortholog); PARTICIPATES IN retino ic acid signaling pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | | | | Pig | 189 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18700476 | RARA | retinoic acid receptor alpha | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); histone deacetylase binding (ortholog); mRNA 5'-UTR binding (ortholog); INVOLVED IN bone development (ortholog); chondroblast differentiation (ortholog); embryonic camera-type eye development (ortholog); PARTICIPATES IN retino ic acid signaling pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | | | | Green Monkey | 188 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922331 | Rara | retinoic acid receptor alpha | ENCODES a protein that exhibits alpha-actinin binding (ortholog); chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN apoptotic cell clearance (ortholog); bone development (ortholog); cellular response to estrogen stimulus (ortholog); PARTICIPATES IN retinoic acid signaling p athway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Naked Mole-Rat | 194 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249411 | rara | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625899051 | Rara | retinoic acid receptor alpha | ENCODES a protein that exhibits alpha-actinin binding (ortholog); chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN apoptotic cell clearance (ortholog); bone development (ortholog); cellular response to estrogen stimulus (ortholog); PARTICIPATES IN retinoic acid signaling p athway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 182 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257894 | rara.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155254959 | rara.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7835326 | RARA-AS1 | RARA antisense RNA 1 | INTERACTS WITH all-trans-retinoic acid; bisphenol A; lipopolysaccharide | 17 | 40340867 | 40343136 | Human | 7 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16572722 | AC080112.4 | novel transcript, antisense to RARA | | | | | Human | | name | gene, lncrna |
| 1564330 | Pram1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN protein-containing complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetr achlorodibenzodioxine | 7 | 15125813 | 15142494 | Rat | 58 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1604582 | PRAM1 | PML-RARA regulated adaptor molecule 1 | The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expre ssion of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). [provided by RefSeq, Jul 2008] | 19 | 8490056 | 8502640 | Human | 67 | old_gene_name , name , description | gene, protein-coding, REVIEWED [RefSeq] |
| 8764333 | Pram1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN protein-containing complex (ortholog) | NW_004955563 | 924365 | 933198 | Chinchilla | 9 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11699449 | PRAM1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN protein-containing complex (ortholog) | 19 | 7775887 | 7789657 | Bonobo | 9 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12401260 | PRAM1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits lipid binding (inferred); protein kinase binding (inferred); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN plasma membrane (inferred); protein-containing complex (inferred) | 20 | 53035389 | 53047126 | Dog | 16 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12613570 | Pram1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits lipid binding (inferred); protein kinase binding (inferred); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN plasma membrane (inferred); protein-containing complex (inferred) | NW_004936588 | 5284001 | 5294900 | Squirrel | 16 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14021948 | PRAM1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits lipid binding (inferred); protein kinase binding (inferred); zinc ion binding (inferred); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN plasma membrane (inferred); protein-containing complex (in ferred) | | | | Pig | 17 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18480696 | PRAM1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN protein-containing complex (ortholog) | | | | Green Monkey | 9 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18928081 | Pram1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN protein-containing complex (ortholog) | | | | Naked Mole-Rat | 16 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 20866418 | PRAM1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits lipid binding (inferred); protein kinase binding (inferred); INVOLVED IN integrin-mediated signaling pathway (inferred); protein localization to plasma membrane (inferred); T cell receptor signaling pathway (inferred); FOUND IN plasma membrane (inferred); protein-cont aining complex (inferred) | | | | Green Monkey | 9 | name | gene, protein-coding |
| 626109677 | Pram1 | PML-RARA regulated adaptor molecule 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN integrin-mediated signaling pathway (ortholog); regulation of neutrophil degranulation (ortholog); FOUND IN protein-containing complex (ortholog) | | | | Black Rat | 9 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1345145 | PML | PML nuclear body scaffold | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor an d tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] | 15 | 73994716 | 74047827 | Human | 517 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1622820 | Pram1 | PML-RAR alpha-regulated adaptor molecule 1 | Predicted to enable protein kinase binding activity. Acts upstream of or within integrin-mediated signaling pathway and regulation of neutrophil degranulation. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in central nervous system; repro ductive system; and stomach. Orthologous to human PRAM1 (PML-RARA regulated adaptor molecule 1). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 33857030 | 33864680 | Mouse | 71 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1318746 | NUMA1 | nuclear mitotic apparatus protein 1 | This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA -weight:700;'>RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] | 11 | 72002864 | 72080542 | Human | 269 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 730906 | STAT5B | signal transducer and activator of transcription 5B | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008] | 17 | 42199177 | 42288370 | Human | 538 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 8734997 | Zbtb16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); cartilage development (ortholog); centra l nervous system development (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (ortholog); nuclear speck (ortholog); nucleus (ortholog) | NW_004955412 | 15668332 | 15845384 | Chinchilla | 82 | description | gene, protein-coding, MODEL [RefSeq] |
| 11790257 | ZBTB16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic digit morphogenesis (ortholog); embryonic hindlimb morp hogenesis (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (inferred); nuclear speck (inferred); nucleus (inferred) | 11 | 108938414 | 109133819 | Bonobo | 94 | description | gene, protein-coding, MODEL [RefSeq] |
| 12146010 | ZBTB16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic digit morphogenesis (ortholog); embryonic hindlimb morp hogenesis (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (inferred); nuclear speck (inferred); nucleus (inferred) | 5 | 19082594 | 19284360 | Dog | 101 | description | gene, protein-coding, MODEL [RefSeq] |
| 12575423 | Zbtb16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic digit morphogenesis (ortholog); embryonic hindlimb morp hogenesis (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (inferred); nuclear speck (inferred); nucleus (inferred) | NW_004936612 | 389877 | 570595 | Squirrel | 94 | description | gene, protein-coding, MODEL [RefSeq] |
| 14199010 | ZBTB16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic digit morphogenesis (ortholog); embryonic hindlimb morp hogenesis (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (inferred); nuclear speck (inferred); nucleus (inferred); INTERACTS WITH zearalenone | | | | Pig | 96 | description | gene, protein-coding, MODEL [RefSeq] |
| 18421994 | ZBTB16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic digit morphogenesis (ortholog); embryonic hindlimb morp hogenesis (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Green Monkey | 94 | description | gene, protein-coding, MODEL [RefSeq] |
| 18917976 | Zbtb16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic digit morphogenesis (ortholog); embryonic hindlimb morp hogenesis (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 94 | description | gene, protein-coding, MODEL [RefSeq] |
| 625871884 | Zbtb16 | zinc finger and BTB domain containing 16 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); cartilage development (ortholog); centra l nervous system development (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); acute promyelocytic leukemia with PLZF/RARA (ortholog); caudal regression syndrome (ortholog); FOUND IN nuclear body (ortholog); nuclear speck (ortholog); nucleus (ortholog) | | | | Black Rat | 82 | description | gene, protein-coding, MODEL [RefSeq] |
| 1318027 | UBA7 | ubiquitin like modifier activating enzyme 7 | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008] | 3 | 49805209 | 49813953 | Human | 162 | description | gene, protein-coding, REVIEWED [RefSeq] |