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36 records found for search term Polr2a
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1352013POLR2ARNA polymerase II subunit AThis gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine a1774843667514616Human296symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1557071Polr2apolymerase (RNA) II (DNA directed) polypeptide AEnables core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription termination; positive regulation of RNA splicing; and transcription by RNA polymerase II. Located in euchromatin and nucleus. Is expressed in several structures, including alimentary116962482369649459Mouse296symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1587326Polr2aRNA polymerase II subunit AENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); DNA-directed RNA polymerase activity (ortholog); INVOLVED IN cellular response to oxygen levels; DNA-templated transcription termination (ortholog); positive regulation of RNA splicing (or105495116254977179Rat200symbol , PhenoGen , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8716185Polr2aRNA polymerase II subunit AENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); DNA-directed RNA polymerase activity (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA sNW_00495546794235409447530Chinchilla83symbolgene, protein-coding, MODEL [RefSeq]
11920715POLR2ARNA polymerase II subunit AENCODES a protein that exhibits DNA-directed RNA polymerase activity (ortholog); kinase binding (ortholog); microfibril binding (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA splicing (ortholog); P1775169407546989Bonobo100symbolgene, protein-coding, MODEL [RefSeq]
12279792POLR2ARNA polymerase II subunit AENCODES a protein that exhibits kinase binding (ortholog); magnesium ion binding (ortholog); microfibril binding (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA splicing (ortholog); PARTICIPATES IN 53240381432429717Dog99symbolgene, protein-coding, MODEL [RefSeq]
12673068Polr2aRNA polymerase II subunit AENCODES a protein that exhibits DNA-directed RNA polymerase activity (ortholog); kinase binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA splicing (ortholog);NW_004936595755585781692Squirrel99symbolgene, protein-coding, MODEL [RefSeq]
14079961POLR2ARNA polymerase II subunit AENCODES a protein that exhibits kinase binding (ortholog); magnesium ion binding (ortholog); microfibril binding (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA splicing (ortholog); PARTICIPATES IN Pig101symbolgene, protein-coding, MODEL [RefSeq]
18512082POLR2ARNA polymerase II subunit AENCODES a protein that exhibits DNA-directed RNA polymerase activity (ortholog); kinase binding (ortholog); microfibril binding (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA splicing (ortholog); PGreen Monkey100symbolgene, protein-coding, MODEL [RefSeq]
18931784Polr2aRNA polymerase II subunit AENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA-directed RNA polymerase activity (ortholog); kinase binding (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNNaked Mole-Rat95symbolgene, protein-coding, MODEL [RefSeq]
405856040polr2aTropical Clawed Frogsymbolgene, null
405856686polr2aTropical Clawed Frogsymbolgene, null
405857830polr2aTropical Clawed Frogsymbolgene, null
405858727polr2aTropical Clawed Frogsymbolgene, null
405860004polr2aTropical Clawed Frogsymbolgene, null
405860827polr2aTropical Clawed Frogsymbolgene, null
405861834polr2aTropical Clawed Frogsymbolgene, null
405863034polr2aTropical Clawed Frogsymbolgene, null
405863745polr2aTropical Clawed Frogsymbolgene, null
405863786polr2aTropical Clawed Frogsymbolgene, null
405863795polr2aTropical Clawed Frogsymbolgene, null
405864519polr2aTropical Clawed Frogsymbolgene, null
405864966polr2aTropical Clawed Frogsymbolgene, null
405865644polr2aTropical Clawed Frogsymbolgene, null
626085227Polr2aRNA polymerase II subunit AENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); DNA-directed RNA polymerase activity (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); DNA-templated transcription termination (ortholog); positive regulation of RNA sBlack Rat83symbolgene, protein-coding, MODEL [RefSeq]
1323374CTDP1CTD phosphatase subunit 1This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), maki187967676879756625Human168old_gene_name , descriptiongene, protein-coding, REVIEWED [RefSeq]
1323393CDC73cell division cycle 73This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltra1193122031193254815Human1838descriptiongene, protein-coding, REVIEWED [RefSeq]
733620GTF2A1general transcription factor IIA subunit 1Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is T148117545281221390Human102descriptiongene, protein-coding, VALIDATED [RefSeq]
737167GTF2A2general transcription factor IIA subunit 2Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), 155963806259657515Human93descriptiongene, protein-coding, VALIDATED [RefSeq]
1606801INTS1integrator complex subunit 1INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat e714702771504389Human142descriptiongene, protein-coding, VALIDATED [RefSeq]
1602701INTS10integrator complex subunit 10INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat 81981741619852067Human71descriptiongene, protein-coding, VALIDATED [RefSeq]
1603031INTS11integrator complex subunit 11The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). 113116001324660Human128descriptiongene, protein-coding, VALIDATED [RefSeq]
1601748INTS12integrator complex subunit 12INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat 4105682627105708689Human61descriptiongene, protein-coding, VALIDATED [RefSeq]
1606257INTS2integrator complex subunit 2INTS2 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat e176186536761927982Human83descriptiongene, protein-coding, VALIDATED [RefSeq]
1603936INTS4integrator complex subunit 4INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat e117787436277994668Human59descriptiongene, protein-coding, VALIDATED [RefSeq]
1602075LEO1LEO1 component of Paf1/RNA polymerase II complexLEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubM155193802551971778Human94descriptiongene, protein-coding, VALIDATED [RefSeq]