| 1310894 | Narf | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (ortholog); FOUND IN lamin filament (ortholog); nuclear lumen (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 107017344 | 107035777 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1322059 | Narf | nuclear prelamin A recognition factor | Predicted to enable lamin binding activity. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in lamin filament. Is expressed in liver lobe; nervous system; and neural retina. Orthologous to human NARF (nuclear prelamin A recognition f actor). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 121128062 | 121146682 | Mouse | 111 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605690 | NARF | nuclear prelamin A recognition factor | Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear prot eins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing. [provided by RefSeq, Jul 2008] | 17 | 82458198 | 82490537 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8840593 | Narf | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (ortholog); FOUND IN lamin filament (ortholog); nuclear lumen (ortholog); nucleolus (ortholog) | NW_004955506 | 636533 | 657561 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11910427 | NARF | nuclear prelamin A recognition factor | ENCODES a protein that exhibits electron transfer activity (inferred); ferredoxin hydrogenase activity (inferred); iron ion binding (inferred); FOUND IN lamin filament (inferred); nuclear lumen (inferred); nucleolus (inferred) | 17 | 76868782 | 76897561 | Bonobo | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12077789 | NARF | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (inferred); FOUND IN lamin filament (inferred); nuclear lumen (inferred); nucleolus (inferred) | | | | Dog | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12553503 | Narf | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (inferred); FOUND IN lamin filament (inferred); nuclear lumen (inferred); nucleolus (inferred) | NW_004936923 | 82257 | 102769 | Squirrel | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13848598 | NARF | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (inferred); FOUND IN lamin filament (inferred); nuclear lumen (inferred); nucleolus (inferred) | | | | Pig | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18619643 | NARF | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (inferred); FOUND IN lamin filament (inferred); nuclear lumen (inferred); nucleolus (inferred) | | | | Green Monkey | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932100 | Narf | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (ortholog); FOUND IN lamin filament (ortholog); nuclear lumen (ortholog); nucleolus (ortholog) | | | | Naked Mole-Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238986 | narf | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626062025 | Narf | nuclear prelamin A recognition factor | ENCODES a protein that exhibits lamin binding (ortholog); FOUND IN lamin filament (ortholog); nuclear lumen (ortholog); nucleolus (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255194 | narf.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155238985 | narf.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 13210589 | NARF-AS1 | NARF antisense RNA 1 | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna |
| 38607426 | NARF-AS2 | NARF antisense RNA 2 | | 17 | 82453186 | 82458519 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 5684564 | NARF-IT1 | NARF intronic transcript 1 | | | | | Human | | symbol , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna |
| 1605080 | RNF138 | ring finger protein 138 | The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefS eq, Jul 2008] | 18 | 32091874 | 32131561 | Human | 105 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1322190 | Trim2 | tripartite motif-containing 2 | Enables ubiquitin protein ligase activity. Involved in regulation of neuron apoptotic process. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; gut; peripheral nervous system ganglion; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Orthologous to human TRIM2 (tripartite motif containing 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 84067746 | 84215659 | Mouse | 187 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16564080 | AC132938.3 | novel transcript, antisense NARF | | | | | Human | | name | gene, lncrna |
| 1314335 | CIAO3 | cytosolic iron-sulfur assembly component 3 | Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Involved in several processes, including intracellular oxygen homeostasis; iron-sulfur cluster assembly; and response to hypoxia. Part of cytosolic [4Fe-4S] assembly targeting complex. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 729765 | 740997 | Human | 67 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1305982 | Ciao3 | cytosolic iron-sulfur assembly component 3 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); intracellular oxygen homeostasis (ortholog); iron-sulfur cluster assembly (ortholog ); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; furan | 10 | 15300403 | 15309467 | Rat | 63 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314336 | Ciao3 | cytosolic iron-sulfur assembly component 3 | Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Acts upstream of or within hematopoietic progenitor cell differentiation and iron-sulfur cluster assembly. Predicted to be part of cytosolic [4Fe-4S] assembly targeting complex. Orthologous to human CIAO3 ( cytosolic iron-sulfur assembly component 3). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 25992750 | 26002306 | Mouse | 74 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9018971 | Ciao3 | cytosolic iron-sulfur assembly component 3 | INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); intracellular oxygen homeostasis (ortholog); iron-sulfur cluster assembly (ortholog); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High M yopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (ortholog) | NW_004955442 | 16465759 | 16475110 | Chinchilla | 13 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11799549 | CIAO3 | cytosolic iron-sulfur assembly component 3 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); iron-sulfur cluster assembly (ortholog); PARTICIPATES IN cytosolic iron-sulfur clus ter protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (inferred) | | | | Bonobo | 15 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12099510 | CIAO3 | cytosolic iron-sulfur assembly component 3 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); iron-sulfur cluster assembly (ortholog); PARTICIPATES IN cytosolic iron-sulfur clus ter protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (inferred) | 6 | 39846782 | 39853952 | Dog | 16 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12581968 | Ciao3 | cytosolic iron-sulfur assembly component 3 | INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); iron-sulfur cluster assembly (ortholog); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (inferred) | NW_004936501 | 277525 | 286929 | Squirrel | 12 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 13878558 | CIAO3 | cytosolic iron-sulfur assembly component 3 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); iron-sulfur cluster assembly (ortholog); PARTICIPATES IN cytosolic iron-sulfur clus ter protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (inferred) | | | | Pig | 16 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18589140 | CIAO3 | cytosolic iron-sulfur assembly component 3 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); iron-sulfur cluster assembly (ortholog); PARTICIPATES IN cytosolic iron-sulfur clus ter protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (inferred) | | | | Green Monkey | 15 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914851 | Ciao3 | cytosolic iron-sulfur assembly component 3 | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); intracellular oxygen homeostasis (ortholog); iron-sulfur cluster assembly (ortholog ); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH hereditary hemorrhagic telangiectasia (ortholog); High Myopia (ortholog); FOUND IN cytosolic [4Fe-4S] assembly targeting complex (ortholog) | | | | Naked Mole-Rat | 16 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
