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Gene: CIAO3 (cytosolic iron-sulfur assembly component 3) Homo sapiens
Symbol: CIAO3
Name: cytosolic iron-sulfur assembly component 3
Description: Predicted to have 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Involved in several processes, including iron-sulfur cluster assembly; oxygen homeostasis; and response to hypoxia. Localizes to the CIA complex; PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; arsane; arsenic atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cytosolic Fe-S cluster assembly factor NARFL; FLJ21988; HPRN; IOP1; iron-only hydrogenase-like protein 1; LET1 like/JFP15; LET1L; NAR1; NARFL; nuclear prelamin A recognition factor like; nuclear prelamin A recognition factor-like; PRN; protein related to Narf
Mus musculus (house mouse) : Ciao3 (cytosolic iron-sulfur assembly component 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ciao3 (cytosolic iron-sulfur assembly component 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ciao3 (cytosolic iron-sulfur assembly component 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CIAO3 (cytosolic iron-sulfur assembly component 3)
Canis lupus familiaris (dog) : CIAO3 (cytosolic iron-sulfur assembly component 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ciao3 (cytosolic iron-sulfur assembly component 3)
Sus scrofa (pig) : CIAO3 (cytosolic iron-sulfur assembly component 3)
Chlorocebus sabaeus (green monkey) : CIAO3 (cytosolic iron-sulfur assembly component 3)
Heterocephalus glaber (naked mole-rat) : Ciao3 (cytosolic iron-sulfur assembly component 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl16729,760 - 741,329 (-)Ensembl
GRCh3816729,765 - 740,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716779,753 - 790,997 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616719,768 - 730,998 (-)NCBINCBI36hg18NCBI36
Celera16979,932 - 991,162 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef16701,355 - 713,420 (-)NCBIHuRef
CHM1_116779,723 - 791,008 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CIAO3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314335
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.