| 1310011 | Mixl1 | Mix paired-like homeobox 1 | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 13 | 94953907 | 94957938 | Rat | 115 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320666 | MIXL1 | Mix paired-like homeobox | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including endodermal cell differentiation; negative regulation of hematopoietic progenitor cell differentiat ion; and positive regulation of mesoderm development. Predicted to act upstream of or within cell migration involved in gastrulation and hemopoiesis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 226223664 | 226227060 | Human | 112 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1320667 | Mixl1 | Mix paired-like homeobox | Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in several processes, including endodermal cell differentiati on; negative regulation of hematopoietic progenitor cell differentiation; and positive regulation of mesoderm development. Acts upstream of or within several processes, including digestive tract development; gastrulation; and hemopoiesis. Located in chromatin and nucleus. Is expressed in several structures, including early embryo; egg cylinder; embryo mesoderm; metanephros; and primitive streak. Orthologous to human MIXL1 (Mix paired-like homeobox). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 180520608 | 180524599 | Mouse | 121 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9065764 | Mixl1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog) | NW_004955489 | 418650 | 422428 | Chinchilla | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11799726 | MIXL1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog) | 1 | 201682488 | 201686358 | Bonobo | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12518945 | Mixl1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (or tholog); endoderm development (ortholog); FOUND IN chromatin (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936526 | 2984900 | 2989494 | Squirrel | 41 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13351420 | MIXL1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); protein homodimerization activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tr act development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog) | 7 | 38651481 | 38652560 | Dog | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18928630 | Mixl1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); protein homodimerization activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive trac t development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog) | | | | Naked Mole-Rat | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13892001 | MIXL1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (or tholog); endoderm development (ortholog); FOUND IN chromatin (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 42 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18521364 | MIXL1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (or tholog); endoderm development (ortholog); FOUND IN chromatin (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 40 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625944993 | Mixl1 | Mix paired-like homeobox | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog) | | | | Black Rat | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 150657640 | MIXL1 | Mix paired-like homeobox | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cell differentiation (inferred); DNA-templated transcription (inf erred); endoderm development (inferred); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Dog | 22 | symbol | gene, protein-coding |