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27 records found for search term Med12
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1350145MED12mediator complex subunit 12The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by tX7111859671142450Human667symbol , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1557537Med12mediator complex subunit 12Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin binding activity; and transcription coactivator activity. Acts upstream of or within several processes, including chordate embryonic development; embryonic brain development; and glial cell development.X100317697100342540Mouse189symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1585896Med12mediator complex subunit 12ENCODES a protein that exhibits ubiquitin protein ligase activity; chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); INVOLVED IN protein ubiquitination; axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); PARTICIPATES IN RNA X7044461570467780Rat156symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8934488Med12mediator complex subunit 12ENCODES a protein that exhibits chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (orthologNW_0049554751068716810710286Chinchilla78symbolgene, protein-coding, MODEL [RefSeq]
11770947MED12mediator complex subunit 12ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); embryonic neurocranium morphogenesis (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATEDX6038682060410730Bonobo84symbolgene, protein-coding, MODEL [RefSeq]
12169673MED12mediator complex subunit 12ENCODES a protein that exhibits chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (orthologX5548762955508941Dog80symbolgene, protein-coding, MODEL [RefSeq]
12732007Med12mediator complex subunit 12ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); embryonic neurocranium morphogenesis (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATEDNW_004936762460342483264Squirrel84symbolgene, protein-coding, MODEL [RefSeq]
18933796Med12mediator complex subunit 12ENCODES a protein that exhibits chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (orthologNaked Mole-Rat81symbolgene, protein-coding, MODEL [RefSeq]
625883250Med12mediator complex subunit 12ENCODES a protein that exhibits chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (orthologBlack Rat73symbolgene, protein-coding, MODEL [RefSeq]
13909430MED12mediator complex subunit 12ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); embryonic neurocranium morphogenesis (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATEDPig84symbolgene, protein-coding, MODEL [RefSeq]
18428179MED12mediator complex subunit 12ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); embryonic neurocranium morphogenesis (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATEDGreen Monkey84symbolgene, protein-coding, MODEL [RefSeq]
286426287med12Tropical Clawed Frogsymbolgene, null
284014867med12.LAfrican Clawed Frogsymbolgene, null
16552801AC004866.2pseudogene similar to part of mediator complex subunit 12 MED12Humannamegene, unprocessed_pseudogene
16552615AC004866.1pseudogene similar to part of mediator complex subunit 12 MED12Humannamegene, processed_pseudogene
1312160Med12lmediator complex subunit 12-likePredicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of mediator complex. Orthologous to human MED12L (mediator complex subunit 12L). [provided by Alli35891282059225867Mouse90symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1352033MED12Lmediator complex subunit 12LThe protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 203151085664151436653Human136symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1592212Med12lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH De2145403318145726317Rat86symbol , PhenoGengene, protein-coding, MODEL [RefSeq]
8886183Med12lmediator complex subunit 12LPARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH Developmental Disease (ortholog); genetic disease (ortholog); intellectual disability (ortholog)NW_00495544822243432530542Chinchilla7symbolgene, protein-coding, MODEL [RefSeq]
11866114MED12Lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coactivator activity (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of transcription by RNA polymerase II (inferred); regulation of trans3148115501148463846Bonobo16symbolgene, protein-coding, MODEL [RefSeq]
12359183MED12Lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH De234570189045987504Dog16symbolgene, protein-coding, MODEL [RefSeq]
12447911Med12lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coactivator activity (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of transcription by RNA polymerase II (inferred); regulation of transNW_00493675813846161656621Squirrel16symbolgene, protein-coding, MODEL [RefSeq]
18922786Med12lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coactivator activity (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of transcription by RNA polymerase II (inferred); regulation of transNaked Mole-Rat16symbolgene, protein-coding, MODEL [RefSeq]
14093376MED12Lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH DePig16symbolgene, protein-coding, MODEL [RefSeq]
18433324MED12Lmediator complex subunit 12LENCODES a protein that exhibits beta-catenin binding (inferred); transcription coactivator activity (inferred); transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of transcription by RNA polymerase II (inferred); regulation of transGreen Monkey16symbolgene, protein-coding, MODEL [RefSeq]
626092880Med12lmediator complex subunit 12LPARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH Developmental Disease (ortholog); genetic disease (ortholog); intellectual disability (ortholog)Black Rat7symbolgene, protein-coding, MODEL [RefSeq]
1312495MED13mediator complex subunit 13This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene exp176194260562065278Human159descriptiongene, protein-coding, REVIEWED [RefSeq]