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52 records found for search term Letm1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1352340LETM1leucine zipper and EF-hand containing transmembrane protein 1This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformat418114791856156Human321symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1359678Letm1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits calcium:proton antiporter activity (ortholog); INVOLVED IN calcium export from the mitochondrion (ortholog); calcium ion transport (ortholog); cristae formation (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Developmental Disabilities (ortholog); E148116726881206776Rat166symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1553847Letm1leucine zipper-EF-hand containing transmembrane protein 1Enables calcium:proton antiporter activity. Involved in calcium export from the mitochondrion; mitochondrial calcium ion homeostasis; and protein complex oligomerization. Located in mitochondrial inner membrane. Is expressed in brain; embryo; gonad; liver; and seminiferous cord. Orthologous to human53389701733940061Mouse169symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8945824Letm1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits calcium:proton antiporter activity (ortholog); INVOLVED IN calcium export from the mitochondrion (ortholog); calcium ion transport (ortholog); cristae formation (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Developmental Disabilities (ortholog); ENW_00495551410401031069297Chinchilla41symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11728464LETM1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits antiporter activity (inferred); calcium ion binding (inferred); calcium:proton antiporter activity (inferred); INVOLVED IN protein hexamerization (ortholog); protein homooligomerization (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Developmental D419530331994958Bonobo45symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12140035LETM1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits antiporter activity (inferred); calcium ion binding (inferred); calcium:proton antiporter activity (inferred); INVOLVED IN calcium export from the mitochondrion (inferred); calcium ion transport (inferred); cristae formation (inferred); ASSOCIATED WITH Craniofacial Ab36226802762304767Dog48symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12668986Letm1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits antiporter activity (inferred); calcium ion binding (inferred); calcium:proton antiporter activity (inferred); INVOLVED IN calcium export from the mitochondrion (inferred); calcium ion transport (inferred); cristae formation (inferred); ASSOCIATED WITH Craniofacial AbNW_0049364772155010421589662Squirrel45symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
13882842LETM1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits antiporter activity (inferred); calcium ion binding (inferred); calcium:proton antiporter activity (inferred); INVOLVED IN calcium export from the mitochondrion (inferred); calcium ion transport (inferred); cristae formation (inferred); ASSOCIATED WITH Craniofacial AbPig49symbol , old_gene_namegene, protein-coding, VALIDATED [RefSeq]
14380558Letm1Flysymbolgene, null
18658814LETM1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits antiporter activity (inferred); calcium ion binding (inferred); calcium:proton antiporter activity (inferred); INVOLVED IN calcium export from the mitochondrion (inferred); calcium ion transport (inferred); cristae formation (inferred); ASSOCIATED WITH Craniofacial AbGreen Monkey45symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18922838Letm1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits antiporter activity (inferred); calcium ion binding (inferred); calcium:proton antiporter activity (inferred); INVOLVED IN cristae formation (ortholog); inner mitochondrial membrane organization (ortholog); mitochondrial calcium ion transmembrane transport (ortholog);Naked Mole-Rat44symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155240646letm1Tropical Clawed Frogsymbolgene, null
625918245Letm1leucine zipper and EF-hand containing transmembrane protein 1ENCODES a protein that exhibits calcium:proton antiporter activity (ortholog); INVOLVED IN calcium export from the mitochondrion (ortholog); calcium ion transport (ortholog); cristae formation (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Developmental Disabilities (ortholog); EBlack Rat41symbolgene, protein-coding, MODEL [RefSeq]
155248506letm1.LAfrican Clawed Frogsymbolgene, null
155240645letm1.SAfrican Clawed Frogsymbolgene, null
626469407LETM1-DTLETM1 divergent transcriptHumansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, ncrna
1344708LETMD1LETM1 domain containing 1This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011]125104822051068958Human95old_gene_name , namegene, protein-coding, REVIEWED [RefSeq]
1552508Letmd1LETM1 domain containing 1Enables molecular adaptor activity. Involved in mitochondrion organization and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including non-canonical NF-kappaB signal transduction; nucleobase-containing compound biosynthetic process; and toll-like re15100360302100377133Mouse119old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1596738Letmd1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinoma (ortholog); FOUND IN mitocho7133461920133476592Rat98old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
8732434Letmd1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinoma (ortholog); FOUND IN mitochoNW_00495554715742101586432Chinchilla27old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12042664LETMD1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (inferred); ribosome binding (inferred); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinoma123768574137705104Bonobo31old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12199580LETMD1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (inferred); ribosome binding (inferred); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinoma2737618803770158Dog31old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12493401Letmd1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (inferred); ribosome binding (inferred); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinomaNW_00493651286845978694074Squirrel31old_gene_name , namegene, protein-coding, MODEL [RefSeq]
13982802LETMD1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (inferred); ribosome binding (inferred); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinomaPig31old_gene_name , namegene, protein-coding, MODEL [RefSeq]
18677024LETMD1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (inferred); ribosome binding (inferred); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinomaGreen Monkey31old_gene_name , namegene, protein-coding, MODEL [RefSeq]
18929400Letmd1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinoma (ortholog); FOUND IN nucleusNaked Mole-Rat29old_gene_name , namegene, protein-coding, MODEL [RefSeq]
625997760Letmd1LETM1 domain containing 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); INVOLVED IN ATP biosynthetic process (ortholog); calcium ion homeostasis (ortholog); gene expression (ortholog); ASSOCIATED WITH breast cancer (ortholog); ovarian carcinoma (ortholog); renal carcinoma (ortholog); FOUND IN mitochoBlack Rat27old_gene_name , namegene, protein-coding, MODEL [RefSeq]
18912413LOC106009575LETM1 domain-containing protein 1 pseudogeneNaked Mole-Ratnamegene, pseudo, MODEL [RefSeq]
18933654LOC101699965LETM1 domain-containing protein LETM2, mitochondrialENCODES a protein that exhibits ribosome binding (inferred); INVOLVED IN intracellular monoatomic cation homeostasis (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)Naked Mole-Rat5namegene, protein-coding, MODEL [RefSeq]
18913079LOC110344069LETM1 domain-containing protein LETM2, mitochondrial-likeNaked Mole-Ratnamegene, pseudo, MODEL [RefSeq]
18922283LOC101711757LETM1 and EF-hand domain-containing protein 1, mitochondrial pseudogeneNaked Mole-Ratnamegene, pseudo, MODEL [RefSeq]
18926718LOC101712211LETM1 and EF-hand domain-containing protein 1, mitochondrial pseudogeneNaked Mole-Ratnamegene, pseudo, MODEL [RefSeq]
16556299AC018442.1leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) pseudogeneHumannamegene, processed_pseudogene
1311220Letm2leucine zipper and EF-hand containing transmembrane protein 2ENCODES a protein that exhibits ribosome binding (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred); INTERACTS WITH 2-methoxyethanol; 3,3',4,4',5-pentachlorobiphenyl; bisphenol A167317176873192336Rat54old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1322565LETM2leucine zipper and EF-hand containing transmembrane protein 2Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial calcium ion transmembrane transport and mitochondrion organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]83838243138409527Human55old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1616469Letm2leucine zipper-EF-hand containing transmembrane protein 2Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial calcium ion transmembrane transport and mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human LETM2 (leucine 82606849426088005Mouse55old_gene_namegene, protein-coding, VALIDATED [RefSeq]
8842726Letm2leucine zipper and EF-hand containing transmembrane protein 2FOUND IN mitochondrion (ortholog)NW_0049554631399035314012911Chinchilla1old_gene_namegene, protein-coding, MODEL [RefSeq]
11927299LETM2leucine zipper and EF-hand containing transmembrane protein 2ENCODES a protein that exhibits ribosome binding (inferred); INVOLVED IN intracellular monoatomic cation homeostasis (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)83768764037711531Bonobo5old_gene_namegene, protein-coding, MODEL [RefSeq]
12236860LETM2leucine zipper and EF-hand containing transmembrane protein 2ENCODES a protein that exhibits ribosome binding (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)162708216727102172Dog8old_gene_namegene, protein-coding, MODEL [RefSeq]
12658000Letm2leucine zipper and EF-hand containing transmembrane protein 2ENCODES a protein that exhibits ribosome binding (inferred); INVOLVED IN intracellular monoatomic cation homeostasis (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)NW_00493671017360101758480Squirrel5old_gene_namegene, protein-coding, MODEL [RefSeq]
14071024LETM2leucine zipper and EF-hand containing transmembrane protein 2ENCODES a protein that exhibits ribosome binding (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)Pig8old_gene_namegene, protein-coding, MODEL [RefSeq]
18755673LETM2leucine zipper and EF-hand containing transmembrane protein 2ENCODES a protein that exhibits ribosome binding (inferred); INVOLVED IN intracellular monoatomic cation homeostasis (inferred); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)Green Monkey5old_gene_namegene, protein-coding, MODEL [RefSeq]
625879802Letm2leucine zipper and EF-hand containing transmembrane protein 2FOUND IN mitochondrion (ortholog)Black Rat1old_gene_namegene, protein-coding, MODEL [RefSeq]
18537413LOC103235417mitochondrial proton/calcium exchanger protein-likeGreen Monkeyold_gene_namegene, pseudo, MODEL [RefSeq]
11717218LOC100976244mitochondrial proton/calcium exchanger protein-like195505620355060484Bonoboold_gene_namegene, pseudo, MODEL [RefSeq]
12499234LOC101971549mitochondrial proton/calcium exchanger protein-likeNW_0049364712688059126882702Squirrelold_gene_namegene, protein-coding, MODEL [RefSeq]
18687520LOC103237676mitochondrial proton/calcium exchanger protein pseudogeneGreen Monkeyold_gene_namegene, pseudo, MODEL [RefSeq]
18406670LOC103245439mitochondrial proton/calcium exchanger protein pseudogeneGreen Monkeyold_gene_namegene, pseudo, MODEL [RefSeq]
11716375LOC103786642mitochondrial proton/calcium exchanger protein-like89634332796345585Bonoboold_gene_namegene, pseudo, MODEL [RefSeq]
2293112LETM1P1leucine zipper and EF-hand containing transmembrane protein 1 pseudogene 1156680856766810669Humansymbol , old_gene_name , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
2293160LETM1P2leucine zipper and EF-hand containing transmembrane protein 1 pseudogene 2195804444058048251Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
2306324LETM1P3leucine zipper and EF-hand containing transmembrane protein 1 pseudogene 389969593299698520Humansymbol , GTEx , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]