Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LETM1 (leucine zipper and EF-hand containing transmembrane protein 1) Homo sapiens
Analyze
Symbol: LETM1
Name: leucine zipper and EF-hand containing transmembrane protein 1
Description: Exhibits calcium:proton antiporter activity. Involved in cellular calcium ion homeostasis; cristae formation; and regulation of cellular hyperosmotic salinity response. Localizes to mitochondrial inner membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LETM1 and EF-hand domain-containing protein 1, mitochondrial; leucine zipper-EF-hand containing transmembrane protein 1; leucine zipper-EF-hand-containing transmembrane protein 1; Mdm38 homolog; SLC55A1
Orthologs:
Related Pseudogenes: LETM1P1   LETM1P2   LETM1P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl41,811,479 - 1,856,156 (-)EnsemblGRCh38hg38GRCh38
GRCh3841,811,479 - 1,856,156 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3741,813,206 - 1,857,974 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,784,558 - 1,827,772 (-)NCBINCBI36hg18NCBI36
Build 3441,781,990 - 1,825,205NCBI
Celera41,725,718 - 1,769,826 (-)NCBI
Cytogenetic Map4p16.3NCBI
HuRef41,756,076 - 1,799,634 (-)NCBIHuRef
CHM1_141,811,156 - 1,856,557 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LETM1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352340
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.