Kcnn2 Gene Search Result

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15 records found for search term Kcnn2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
2963	Kcnn2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits calmodulin binding; small conductance calcium-activated potassium channel activity; alpha-actinin binding (ortholog); INVOLVED IN positive regulation of potassium ion transport; potassium ion transport; regulation of neuronal synaptic plasticity; PARTICIPATES IN calci ... (more) um/calcium-mediated signaling pathway; bile acid transport pathway; ASSOCIATED WITH tremors; ASSOCIATED WITH alcohol use disorder; essential tremor; atrial fibrillation (ortholog); FOUND IN dendritic spine; membrane; neuronal cell body; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; acetamide	18	40004693	40445043	Rat	217	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
734125	KCNN2	potassium calcium-activated channel subfamily N member 2	Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potas ... (more) sium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]	5	114055978	114496496	Human	259	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
734126	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	Enables small conductance calcium-activated potassium channel activity. Involved in membrane repolarization during atrial cardiac muscle cell action potential; modulation of chemical synaptic transmission; and potassium ion transmembrane transport. Located in several cellular components, including T ... (more) -tubule; Z disc; and smooth endoplasmic reticulum. Is active in glutamatergic synapse and postsynaptic membrane. Is expressed in brain; heart; and heart ventricle. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in myoclonic dystonia 34. Orthologous to human KCNN2 (potassium calcium-activated channel subfamily N member 2). [provided by Alliance of Genome Resources, Jul 2025]	18	45401754	45818954	Mouse	248	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8973442	Kcnn2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calcium-activated potassium channel activity (ortholog); calmodulin binding (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (o ... (more) rtholog); monoatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)	NW_004955408	34223523	34366191	Chinchilla	60	symbol	gene, protein-coding, MODEL [RefSeq]
11800057	KCNN2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calmodulin binding (ortholog); monoatomic ion channel activity (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (ortholog); mon ... (more) oatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)	5	109722916	109862747	Bonobo	56	symbol	gene, protein-coding, MODEL [RefSeq]
12247289	KCNN2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calmodulin binding (ortholog); inward rectifier potassium channel activity (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (or ... (more) tholog); monoatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)	11	4279362	4423080	Dog	61	symbol	gene, protein-coding, MODEL [RefSeq]
12626373	Kcnn2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calmodulin binding (ortholog); inward rectifier potassium channel activity (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (or ... (more) tholog); monoatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)	NW_004937043	133981	269593	Squirrel	55	symbol	gene, protein-coding, MODEL [RefSeq]
18908090	Kcnn2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calmodulin binding (ortholog); inward rectifier potassium channel activity (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (or ... (more) tholog); monoatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)				Naked Mole-Rat	55	symbol	gene, protein-coding, MODEL [RefSeq]
14147048	KCNN2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calmodulin binding (ortholog); inward rectifier potassium channel activity (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (or ... (more) tholog); monoatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)				Pig	61	symbol	gene, protein-coding, MODEL [RefSeq]
626103284	Kcnn2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calcium-activated potassium channel activity (ortholog); calmodulin binding (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (o ... (more) rtholog); monoatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)				Black Rat	60	symbol	gene, protein-coding, MODEL [RefSeq]
18534831	KCNN2	potassium calcium-activated channel subfamily N member 2	ENCODES a protein that exhibits alpha-actinin binding (ortholog); calmodulin binding (ortholog); monoatomic ion channel activity (ortholog); INVOLVED IN membrane repolarization during atrial cardiac muscle cell action potential (ortholog); modulation of chemical synaptic transmission (ortholog); mon ... (more) oatomic ion transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atrial fibrillation (ortholog); cardiac arrest (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)				Green Monkey	56	symbol	gene, protein-coding, MODEL [RefSeq]
155237451	kcnn2						Tropical Clawed Frog		symbol	gene, null
155237452	kcnn2.L						African Clawed Frog		symbol	gene, null
155256568	kcnn2.S						African Clawed Frog		symbol	gene, null
149735330	Kcnn2^Trdk	potassium calcium-activated channel subfamily N member 2; Trdk mutant	ASSOCIATED WITH tremors; ASSOCIATED WITH essential tremor				Rat	2	symbol , description	gene, allele