| 1343257 | IER2 | immediate early response 2 | Predicted to enable DNA binding activity. Involved in cell motility and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleoplasm. Implicated in colorectal cancer and hepatocellular carcinoma. Biomarker of childhood acute myeloid leukemia; colorectal adenocarcin oma; hepatocellular carcinoma; and melanoma. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 13150411 | 13154911 | Human | 191 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1359581 | Ier2 | immediate early response 2 | INVOLVED IN neuron differentiation; response to fibroblast growth factor; cell motility (ortholog); ASSOCIATED WITH Lymphatic Metastasis; childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTE RACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 19 | 40399373 | 40400897 | Rat | 196 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1552809 | Ier2 | immediate early response 2 | Predicted to be involved in several processes, including neuron differentiation; positive regulation of transcription by RNA polymerase II; and response to fibroblast growth factor. Located in cytoplasm. Is expressed in several structures, including ear; forelimb bud; submandibular gland primordium; tooth; and vibrissa. Human ortholog(s) of this gene implicated in colorectal cancer and hepatocellular carcinoma. Orthologous to human IER2 (immediate early response 2). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 85387960 | 85389481 | Mouse | 198 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8847881 | Ier2 | immediate early response 2 | INVOLVED IN cell motility (ortholog); neuron differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (ortholog ); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955415 | 32159762 | 32161530 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11928399 | IER2 | immediate early response 2 | INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 19 | 12714804 | 12718213 | Bonobo | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12070396 | IER2 | immediate early response 2 | INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 20 | 49071243 | 49074184 | Dog | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12458324 | Ier2 | immediate early response 2 | INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936659 | 2176962 | 2179900 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18917743 | Ier2 | immediate early response 2 | INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13857160 | IER2 | immediate early response 2 | INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285059926 | ier2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626104555 | Ier2 | immediate early response 2 | INVOLVED IN cell motility (ortholog); neuron differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (ortholog ); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18526926 | IER2 | immediate early response 2 | INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH childhood acute myeloid leukemia (ortholog); colorectal adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 286733112 | ier2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 285060163 | ier2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 597538579 | IER2-AS1 | IER2 antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |
| 16564730 | AC011446.2 | novel transcript, antisense to IER2 | | | | | Human | | name | gene, lncrna |
| 16572387 | AC011446.3 | novel transcript, antisense to IER2 | | | | | Human | | name | gene, lncrna |