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Gene: IER2 (immediate early response 2) Homo sapiens
Symbol: IER2
Name: immediate early response 2
Description: ENCODES a protein that exhibits DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding; INVOLVED IN cell motility; positive regulation of transcription by RNA polymerase II; neuron differentiation (ortholog); ASSOCIATED WITH Lung Neoplasms; Marshall-Smith syndrome; FOUND IN cytoplasm; nucleoplasm; nucleus; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3-dimethoxynaphthalene-1,4-dione
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chxI protein homolog; ETR101; immediate early response gene 2 protein; MGC111472; MGC15265
Mus musculus (house mouse) : Ier2 (immediate early response 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ier2 (immediate early response 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ier2 (immediate early response 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IER2 (immediate early response 2)
Canis lupus familiaris (dog) : IER2 (immediate early response 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ier2 (immediate early response 2)
Sus scrofa (pig) : IER2 (immediate early response 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381913,150,411 - 13,154,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,261,282 - 13,265,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361913,122,282 - 13,126,722 (+)NCBINCBI36hg18NCBI36
Build 341913,122,281 - 13,126,716NCBI
Celera1913,151,680 - 13,156,120 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,833,675 - 12,838,116 (+)NCBIHuRef
CHM1_11913,262,236 - 13,266,676 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IER2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343257
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.