Htr1a Gene Search Result

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17 records found for search term Htr1a

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
2845	Htr1a	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity; G-protein alpha-subunit binding; serotonin binding; INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway; behavioral response to nicotine; negative regulation of gamma-aminobutyric acid secretion; ... (more) PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol use disorder; anxiety disorder; Catalepsy; FOUND IN axon hillock; GABA-ergic synapse; neuronal cell body; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1-(3-chlorophenyl)piperazine	2	38427169	38431733	Rat	331	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
10745	Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	Enables G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; regulation of serotonin secretion; and serotonin receptor signaling pathway. Acts upstream of or within adult behavior and gamma-aminobutyric acid signaling pathway. Predicted to ... (more) be located in axon hillock. Predicted to be active in GABA-ergic synapse; dendrite; and presynaptic membrane. Is expressed in several structures, including central nervous system; exocrine gland; eye; genitourinary system; and intestine. Used to study anxiety disorder. Human ortholog(s) of this gene implicated in alcohol dependence; anxiety disorder (multiple); depressive disorder; substance abuse; and withdrawal disorder. Orthologous to human HTR1A (5-hydroxytryptamine receptor 1A). [provided by Alliance of Genome Resources, Jul 2025]	13	105580040	105584630	Mouse	374	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
69020	HTR1A	5-hydroxytryptamine receptor 1A	This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consisten ... (more) t with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]	5	63957874	63962445	Human	341	symbol , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
8965628	Htr1a	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); Gi/o-coupled serotonin receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral fear respons ... (more) e (ortholog); behavioral response to nicotine (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)	NW_004955446	4913181	4917726	Chinchilla	115	symbol	gene, protein-coding, MODEL [RefSeq]
11823349	HTR1A	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); serotonin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral response to nicotine (ortholog); ga ... (more) mma-aminobutyric acid signaling pathway (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)	5	50045266	50049636	Bonobo	132	symbol	gene, protein-coding, MODEL [RefSeq]
12113428	HTR1A	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); Gi/o-coupled serotonin receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral fear respons ... (more) e (ortholog); behavioral response to nicotine (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)	2	50005277	50006548	Dog	134	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
12663985	Htr1a	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); serotonin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral response to nicotine (ortholog); ga ... (more) mma-aminobutyric acid signaling pathway (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)	NW_004936480	5042531	5047157	Squirrel	129	symbol	gene, protein-coding, MODEL [RefSeq]
14169346	HTR1A	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); serotonin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral response to nicotine (ortholog); ga ... (more) mma-aminobutyric acid signaling pathway (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)				Pig	130	symbol	gene, protein-coding, MODEL [RefSeq]
155250765	htr1a						Tropical Clawed Frog		symbol	gene, null
18936160	Htr1a	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); Gi/o-coupled serotonin receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral response to ... (more) nicotine (ortholog); gamma-aminobutyric acid signaling pathway (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)				Naked Mole-Rat	128	symbol	gene, protein-coding, MODEL [RefSeq]
626055483	Htr1a	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); Gi/o-coupled serotonin receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral fear respons ... (more) e (ortholog); behavioral response to nicotine (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)				Black Rat	115	symbol	gene, protein-coding, MODEL [RefSeq]
18700515	HTR1A	5-hydroxytryptamine receptor 1A	ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); serotonin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral response to nicotine (ortholog); ga ... (more) mma-aminobutyric acid signaling pathway (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)				Green Monkey	132	symbol	gene, protein-coding, MODEL [RefSeq]
155258446	htr1a.L						African Clawed Frog		symbol	gene, null
155250230	htr1a.S						African Clawed Frog		symbol	gene, null
1581496	Htr1a^m1Mcwi	5-hydroxytryptamine receptor 1A; mutation 1, Medical College of Wisconsin	mutation generated by ENU (N-ethyl-N-nitrourea); C266Y mutation is generated from the codon change TGT/TAT				Rat		symbol , old_gene_symbol	gene, allele
1599562	Htr1a^m2Mcwi	5-hydroxytryptamine receptor 1A; mutation 2, Medical College of Wisconsin	mutation generated by ENU (N-ethyl-N-nitrourea); G76R mutation is generated from the codon change GGC/CGC				Rat		symbol , old_gene_symbol	gene, allele
16558099	AC122707.1	novel transcript, sense overlapping HTR1A					Human		name	gene, lncrna