HTR1A (5-hydroxytryptamine receptor 1A) - Rat Genome Database

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Gene: HTR1A (5-hydroxytryptamine receptor 1A) Sus scrofa
Analyze
Symbol: HTR1A
Name: 5-hydroxytryptamine receptor 1A
RGD ID: 14169346
Description: ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); receptor-receptor interaction (ortholog); INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway (ortholog); behavioral fear response (ortholog); exploration behavior (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); anxiety disorder (ortholog); Apnea (ortholog); FOUND IN axon hillock (ortholog); GABA-ergic synapse (ortholog); integral component of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11642,479,812 - 42,484,365 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21645,547,917 - 45,550,733 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:18653286  


Genomics

Comparative Map Data
HTR1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11642,479,812 - 42,484,365 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21645,547,917 - 45,550,733 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HTR1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl563,957,874 - 63,962,507 (-)EnsemblGRCh38hg38GRCh38
GRCh38563,957,874 - 63,962,445 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37563,253,701 - 63,258,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36563,292,034 - 63,293,302 (-)NCBINCBI36hg18NCBI36
Build 34563,292,033 - 63,293,302NCBI
Celera560,253,209 - 60,254,477 (-)NCBI
Cytogenetic Map5q12.3NCBI
HuRef560,210,553 - 60,212,797 (-)NCBIHuRef
CHM1_1563,255,560 - 63,257,804 (-)NCBICHM1_1
Htr1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913105,580,201 - 105,584,641 (+)NCBIGRCm39mm39
GRCm39 Ensembl13105,580,147 - 105,584,630 (+)Ensembl
GRCm3813105,443,693 - 105,448,133 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13105,443,639 - 105,448,122 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713106,233,773 - 106,238,213 (+)NCBIGRCm37mm9NCBIm37
MGSCv3613106,564,148 - 106,568,501 (+)NCBImm8
Celera13109,835,550 - 109,839,989 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.92NCBI
Htr1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2236,694,174 - 36,695,442 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl236,694,174 - 36,695,442 (+)Ensembl
Rnor_6.0236,246,628 - 36,247,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl236,246,628 - 36,247,896 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0255,362,662 - 55,363,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4236,434,518 - 36,435,786 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1236,354,886 - 36,356,155 (+)NCBI
Celera232,636,756 - 32,638,024 (+)NCBICelera
RH 3.4 Map2156.5RGD
Cytogenetic Map2q13NCBI
Htr1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554464,913,884 - 4,915,146 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554464,913,181 - 4,917,726 (+)NCBIChiLan1.0ChiLan1.0
HTR1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1551,691,853 - 51,696,257 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl551,692,416 - 51,693,684 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0550,045,266 - 50,049,636 (+)NCBIMhudiblu_PPA_v0panPan3
HTR1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1250,005,277 - 50,006,548 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl250,002,740 - 50,006,548 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha246,962,303 - 46,963,574 (-)NCBI
ROS_Cfam_1.0250,490,014 - 50,491,285 (-)NCBI
UMICH_Zoey_3.1247,550,689 - 47,551,960 (-)NCBI
UNSW_CanFamBas_1.0248,341,999 - 48,343,270 (-)NCBI
UU_Cfam_GSD_1.0249,236,031 - 49,237,302 (-)NCBI
Htr1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213196,105,986 - 196,110,702 (+)NCBI
SpeTri2.0NW_0049364805,042,531 - 5,047,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTR1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1460,159,542 - 60,162,947 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl460,159,944 - 60,161,212 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660498,232,890 - 8,758,394 (-)NCBIVero_WHO_p1.0
Htr1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248155,817,196 - 5,821,197 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005672476   ⟹   XP_005672533
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11642,479,812 - 42,484,365 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005672533 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005672533   ⟸   XM_005672476
- UniProtKB: F1SKV3 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00070019300 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00070031931 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00070038151 UniProtKB/TrEMBL
InterPro 5HT1A_rcpt UniProtKB/TrEMBL
  5HT_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report ssc:100526081 UniProtKB/TrEMBL
NCBI Gene HTR1A ENTREZGENE
PANTHER PTHR24247:SF20 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS 5HT1ARECEPTR UniProtKB/TrEMBL
  5HTRECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
UniProt A0A4X1UTF5_PIG UniProtKB/TrEMBL
  F1SKV3 ENTREZGENE