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36 records found for search term Hgs
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
69225Hgshepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); ubiquitin-like protein ligase binding (ortholog); INVOLVED IN endosome to lysosome transport; membrane invagination (ortholog); negative regulation of angiogenesis (ortholog); PARTICIPAT10106237988106256174Rat153symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
733649HGShepatocyte growth factor-regulated tyrosine kinase substrateThe protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [pro178168401181702121Human166symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
733650HgsHGF-regulated tyrosine kinase substrateEnables identical protein binding activity and ubiquitin-modified protein reader activity. Predicted to be involved in several processes, including lysosomal transport; negative regulation of signal transduction; and positive regulation of exosomal secretion. Located in cytoplasm. Is expressed in se11120358431120374810Mouse198symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8880101Hgshepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); ubiquitin-like protein ligase binding (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); membrane invagination (ortholog); negative regulation of angiogenesis (ortholog);NW_00495550614055431418095Chinchilla63symbolgene, protein-coding, MODEL [RefSeq]
11784633HGShepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); regulation of MAP kinase activity (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor sign177614321276161469Bonobo81symbolgene, protein-coding, MODEL [RefSeq]
12413237HGShepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); regulation of MAP kinase activity (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor sign9499071513375Dog80symbolgene, protein-coding, VALIDATED [RefSeq]
12594236Hgshepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); regulation of MAP kinase activity (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor signNW_00493659452856785301267Squirrel80symbolgene, protein-coding, MODEL [RefSeq]
13910423HGShepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); regulation of MAP kinase activity (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor signPig81symbolgene, protein-coding, MODEL [RefSeq]
18422151HGShepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); regulation of MAP kinase activity (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor signGreen Monkey80symbolgene, protein-coding, MODEL [RefSeq]
18919411Hgshepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-like protein ligase binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); membrane invagination (ortholog); negative regulation of angiogenesis Naked Mole-Rat79symbolgene, protein-coding, MODEL [RefSeq]
155239303hgsTropical Clawed Frogsymbolgene, null
626136110Hgshepatocyte growth factor-regulated tyrosine kinase substrateENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); ubiquitin-like protein ligase binding (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); membrane invagination (ortholog); negative regulation of angiogenesis (ortholog);Black Rat63symbolgene, protein-coding, MODEL [RefSeq]
155239304hgs.LAfrican Clawed Frogsymbolgene, null
405858174hgs.SAfrican Clawed Frogsymbolgene, null
405858863hgs.SAfrican Clawed Frogsymbolgene, null
405860341hgs.SAfrican Clawed Frogsymbolgene, null
405860560hgs.SAfrican Clawed Frogsymbolgene, null
626187927hgs.SAfrican Clawed Frogsymbolgene, null
16563504AC139530.1novel transcript, antisense to HGSHumannamegene, lncrna
16567709AC139530.3novel transcript, antisense to HGSHumannamegene, lncrna
1560755Hgsnatheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (ortholog); heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); lysosomal transport (ortholog); protein complex oligomerization (ortholog); ASSOCIATED WITH167280796772840180Rat108symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1606456HGSNATheparan-alpha-glucosaminide N-acetyltransferaseThis gene encodes a lysosomal acetyltransferase, which is one of several enzymes involved in the lysosomal degradation of heparin sulfate. Mutations in this gene are associated with Sanfilippo syndrome C, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired84314046443202855Human484symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1623253Hgsnatheparan-alpha-glucosaminide N-acetyltransferaseEnables heparan-alpha-glucosaminide N-acetyltransferase activity. Involved in heparan sulfate proteoglycan catabolic process. Is active in lysosomal lumen. Is expressed in central nervous system; eye; and long bone epiphyseal plate. Used to study mucopolysaccharidosis III and mucopolysaccharidosis t82643249526466704Mouse159symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9045764Hgsnatheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (ortholog); heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); lysosomal transport (ortholog); protein complex oligomerization (ortholog); ASSOCIATED WITHNW_0049554571335196313386521Chinchilla23symbolgene, protein-coding, MODEL [RefSeq]
11830980HGSNATheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (ortholog); heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); lysosomal transport (ortholog); protein complex oligomerization (ortholog); ASSOCIATED WITH84238840642448466Bonobo23symbolgene, protein-coding, MODEL [RefSeq]
12188083HGSNATheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (ortholog); heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); protein complex oligomerization (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog)162264091222683733Dog24symbolgene, protein-coding, MODEL [RefSeq]
12684055Hgsnatheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (inferred); heparan-alpha-glucosaminide N-acetyltransferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan catabolic process (inferred); lysosomal transport (inferred); protein complex oligomerization (inferred); ASSOCIATED WITHNW_004936570257636297797Squirrel22symbolgene, protein-coding, MODEL [RefSeq]
14297074HGSNATheparan-alpha-glucosaminide N-acetyltransferasePig2symbolgene, protein-coding, MODEL [RefSeq]
18668001HGSNATheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN lysosomal lumGreen Monkey25symbolgene, protein-coding, MODEL [RefSeq]
18913095Hgsnatheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (ortholog); heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); protein complex oligomerization (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog)Naked Mole-Rat24symbolgene, protein-coding, MODEL [RefSeq]
285571774hgsnatTropical Clawed Frogsymbolgene, null
626150229Hgsnatheparan-alpha-glucosaminide N-acetyltransferaseENCODES a protein that exhibits acyltransferase activity (ortholog); heparan-alpha-glucosaminide N-acetyltransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan catabolic process (ortholog); lysosomal transport (ortholog); protein complex oligomerization (ortholog); ASSOCIATED WITHBlack Rat22symbolgene, protein-coding, MODEL [RefSeq]
285572282hgsnat.LAfrican Clawed Frogsymbolgene, null
1606879GSTK1glutathione S-transferase kappa 1This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the remo7143263441143269115Human236old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1349768GSTM3glutathione S-transferase mu 3Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encod1109733937109741038Human446old_gene_namegene, protein-coding, REVIEWED [RefSeq]
1601696FAM174Afamily with sequence similarity 174 member APredicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]5100535374100586741Human58old_gene_namegene, protein-coding, VALIDATED [RefSeq]