| 1310802 | Gabpa | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN blastocyst formation (ortholog); ERBB signaling pathway (or tholog); in utero embryonic development (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (R)-noradrenaline; (R,R,R)-alpha-tocopherol; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | 11 | 37375040 | 37404060 | Rat | 144 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321915 | GABPA | GA binding protein transcription factor subunit alpha | This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010] | 21 | 25734972 | 25772460 | Human | 139 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1321916 | Gabpa | GA repeat binding protein, alpha | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Acts upstream of or within blastocyst formation; negative regulation of megakaryocyte differentiation; and negative regulation of transcription by RNA polymerase II. Located in nucl eus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GABPA (GA binding protein transcription factor subunit alpha). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 84631795 | 84660671 | Mouse | 158 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8909781 | Gabpa | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN blastocyst formation (ortholog); ERBB signaling pathway (or tholog); in utero embryonic development (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955407 | 25609840 | 25641886 | Chinchilla | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11816679 | GABPA | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN blastocyst formation (ortholog); in utero embryonic development (ortholog); negative regulation of megakaryocyte diff erentiation (ortholog); FOUND IN nucleus (ortholog) | 21 | 12179921 | 12217851 | Bonobo | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12196916 | GABPA | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN blastocyst formation (ortholog); in utero embryonic development (ortholog); negative regulation of megakaryocyte diff erentiation (ortholog); FOUND IN chromatin (inferred); nucleoplasm (inferred); nucleus (inferred) | 31 | 21216931 | 21251658 | Dog | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12714187 | Gabpa | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN blastocyst formation (ortholog); in utero embryonic development (ortholog); negative regulation of megakaryocyte diff erentiation (ortholog); FOUND IN nucleus (ortholog) | NW_004936640 | 1882297 | 1917210 | Squirrel | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626094660 | Gabpa | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN blastocyst formation (ortholog); ERBB signaling pathway (or tholog); in utero embryonic development (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932564 | Gabpa | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN blastocyst formation (ortholog); in utero embryonic development (ortholog); negative regulation of megakaryocyte diff erentiation (ortholog); FOUND IN nucleus (ortholog) | | | | Naked Mole-Rat | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18783083 | GABPA | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN blastocyst formation (ortholog); in utero embryonic development (ortholog); negative regulation of megakaryocyte diff erentiation (ortholog); FOUND IN nucleus (ortholog) | | | | Green Monkey | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249839 | gabpa | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13923448 | GABPA | GA binding protein transcription factor subunit alpha | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN blastocyst formation (ortholog); in utero embryonic development (ortholog); negative regulation of megakaryocyte diff erentiation (ortholog); FOUND IN chromatin (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256998 | gabpa.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236060 | gabpa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1605717 | GABPAP | GABPA pseudogene | | 7 | 63893249 | 63897908 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 12204053 | GABPB1 | GA binding protein transcription factor subunit beta 1 | ENCODES a protein that exhibits transcription cis-regulatory region binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | 30 | 16239321 | 16303701 | Dog | 20 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14222454 | GABPB1 | GA binding protein transcription factor subunit beta 1 | ENCODES a protein that exhibits transcription cis-regulatory region binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 20 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 13851040 | GABPB2 | GA binding protein transcription factor subunit beta 2 | ENCODES a protein that exhibits identical protein binding (inferred); transcription cis-regulatory region binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 14 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |