| 1350548 | FLRT3 | fibronectin leucine rich transmembrane protein 3 | This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues . Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010] | 20 | 14322985 | 14337612 | Human | 227 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1558376 | Flrt3 | fibronectin leucine rich transmembrane protein 3 | Enables chemorepellent activity and fibroblast growth factor receptor binding activity. Involved in several processes, including fibroblast growth factor receptor signaling pathway; proepicardium cell migration involved in pericardium morphogenesis; and synapse organization. Acts upstream of or with in positive regulation of synapse assembly. Located in several cellular components, including axonal growth cone; cell-cell junction; and extracellular space. Is active in glutamatergic synapse and postsynaptic membrane. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system; brain; embryo ectoderm; embryo mesenchyme; and eye. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 21 with or without anosmia. Orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 140500118 | 140513396 | Mouse | 210 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566005 | Flrt3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (ortholog); fibroblast growth factor receptor binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN axon guidance; neuron projection development; neuron projection extension; ASSOCIATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus; plasma membrane; synaptic membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 148448115 | 148461458 | Rat | 198 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9063569 | Flrt3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (ortholog); fibroblast growth factor receptor binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN axon guidance (ortholog); cell-cell adhesion (ortholog); embryonic morphogenesis (ortholog); ASSOCIATED WITH hypogonadot ropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); axonal growth cone (ortholog); cell-cell junction (ortholog) | NW_004955415 | 23669749 | 23683235 | Chinchilla | 39 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11848651 | FLRT3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCI ATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); synaptic membrane (ortholog) | 20 | 14294903 | 14310584 | Bonobo | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12201011 | FLRT3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCI ATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); synaptic membrane (ortholog) | 24 | 8354151 | 8367601 | Dog | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12580140 | Flrt3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCI ATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); synaptic membrane (ortholog) | NW_004936485 | 5532554 | 5547430 | Squirrel | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18926851 | Flrt3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCI ATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); synaptic membrane (ortholog) | | | | Naked Mole-Rat | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625838164 | Flrt3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (ortholog); fibroblast growth factor receptor binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN axon guidance (ortholog); cell-cell adhesion (ortholog); embryonic morphogenesis (ortholog); ASSOCIATED WITH hypogonadot ropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); axonal growth cone (ortholog); cell-cell junction (ortholog) | | | | Black Rat | 39 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18777209 | FLRT3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCI ATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); synaptic membrane (ortholog) | | | | Green Monkey | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13977947 | FLRT3 | fibronectin leucine rich transmembrane protein 3 | ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCI ATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); Spontaneous Abortions (ortholog); FOUND IN axon terminus (ortholog); synaptic membrane (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 46 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155235767 | flrt3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155248832 | flrt3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246531 | flrt3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 12184732 | LOC102156506 | leucine-rich repeat transmembrane protein FLRT3-like | | 9 | 56302386 | 56306382 | Dog | | name | gene, protein-coding, MODEL [RefSeq] |
| 1345456 | FLRT1 | fibronectin leucine rich transmembrane protein 1 | This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein share s sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008] | 11 | 64035931 | 64119171 | Human | 106 | description | gene, protein-coding, REVIEWED [RefSeq] |