| 2599 | Fcer1g | Fc epsilon receptor Ig | ENCODES a protein that exhibits protein heterodimerization activity; protein homodimerization activity; identical protein binding (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous pept ide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; asthma pathway; tuberculosis pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN Fc-gamma receptor III complex; cell surface (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 13 | 86181908 | 86186766 | Rat | 218 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10572 | Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | Enables IgE receptor activity; identical protein binding activity; and immunoglobulin binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of interleukin-4 production; and serotonin secretion by platelet. Acts upstream of or within s everal processes, including immune response-regulating cell surface receptor signaling pathway; positive regulation of cytokine production; and positive regulation of immune effector process. Located in external side of plasma membrane. Part of Fc-epsilon receptor I complex. Is expressed in central nervous system; gut; male reproductive gland or organ; and retina. Orthologous to human FCER1G (Fc epsilon receptor Ig). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 171057141 | 171061918 | Mouse | 348 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736226 | FCER1G | Fc epsilon receptor Ig | The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008] | 1 | 161215295 | 161219245 | Human | 231 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8906293 | Fcer1g | Fc fragment of IgE receptor Ig | ENCODES a protein that exhibits identical protein binding (ortholog); IgE binding (ortholog); IgE receptor activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen vi a MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); Fc-epsilon receptor I complex (ortholog) | NW_004955468 | 12971931 | 12975206 | Chinchilla | 89 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11704552 | FCER1G | Fc epsilon receptor Ig | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN Fc-gamma receptor III complex (ortholog) | 1 | 136627672 | 136631696 | Bonobo | 109 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12321608 | FCER1G | Fc epsilon receptor Ig | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); Fc-epsilon receptor I complex (inferred) | 38 | 21267841 | 21271036 | Dog | 107 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12716629 | Fcer1g | Fc fragment of IgE receptor Ig | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); Fc-epsilon receptor I complex (inferred) | NW_004936903 | 514278 | 517975 | Squirrel | 107 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14062623 | FCER1G | Fc epsilon receptor Ig | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); Fc-epsilon receptor I complex (inferred) | | | | Pig | 96 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626176580 | fcer1g | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626186138 | fcer1g | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626187189 | fcer1g | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18935777 | Fcer1g | Fc fragment of IgE receptor Ig | ENCODES a protein that exhibits identical protein binding (ortholog); IgE binding (ortholog); IgE receptor activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen vi a MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); Fc-epsilon receptor I complex (ortholog) | | | | Naked Mole-Rat | 89 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18523274 | FCER1G | Fc epsilon receptor Ig | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); Fc-epsilon receptor I complex (inferred) | | | | Green Monkey | 107 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625973337 | Fcer1g | Fc fragment of IgE receptor Ig | ENCODES a protein that exhibits identical protein binding (ortholog); IgE binding (ortholog); IgE receptor activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen vi a MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); Fc-epsilon receptor I complex (ortholog) | | | | Black Rat | 89 | symbol | gene, protein-coding, MODEL [RefSeq] |