FCER1G (Fc epsilon receptor Ig) - Rat Genome Database

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Pathways
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Gene: FCER1G (Fc epsilon receptor Ig) Sus scrofa
Analyze
Symbol: FCER1G
Name: Fc epsilon receptor Ig
RGD ID: 14062623
Description: ENCODES a protein that exhibits IgE binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fc epsilon receptor gamma chain; Fc fragment of IgE receptor Ig; Fc receptor gamma-chain; fc-epsilon RI-gamma; fceRI gamma; fcRgamma; high affinity immunoglobulin epsilon receptor subunit gamma; igE Fc receptor subunit gamma
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,242,472 - 89,246,450 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,242,467 - 89,246,344 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,099,149 - 97,103,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antigen processing and presentation of exogenous peptide antigen via MHC class I  (IBA,ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IBA,ISO)
cell surface receptor signaling pathway  (IEA,ISO)
cellular response to low-density lipoprotein particle stimulus  (ISS)
defense response to bacterium  (IBA,ISO)
Fc receptor mediated stimulatory signaling pathway  (IBA,ISO)
Fc-epsilon receptor signaling pathway  (IEA)
Fc-gamma receptor signaling pathway  (IBA,ISO)
immune system process  (IEA)
immunoglobulin mediated immune response  (IBA,ISO)
innate immune response  (IBA,IEA,ISO)
integrin-mediated signaling pathway  (ISO)
interleukin-3-mediated signaling pathway  (ISS)
mast cell activation  (ISO)
mast cell apoptotic process  (ISO)
mast cell degranulation  (ISO)
negative regulation of mast cell apoptotic process  (ISO)
neutrophil activation involved in immune response  (IBA)
neutrophil chemotaxis  (IBA,ISO)
osteoclast differentiation  (ISO)
phagocytosis, engulfment  (ISO)
positive regulation of immune response  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-4 production  (ISS)
positive regulation of interleukin-6 production  (ISO)
positive regulation of mast cell cytokine production  (ISO)
positive regulation of mast cell degranulation  (ISO)
positive regulation of phagocytosis  (IBA,ISO)
positive regulation of protein localization to cell surface  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of type I hypersensitivity  (ISO)
positive regulation of type IIa hypersensitivity  (ISO)
positive regulation of type III hypersensitivity  (ISO)
protein localization to plasma membrane  (ISO)
receptor internalization  (ISS)
regulation of immune response  (ISO)
regulation of platelet activation  (IBA)
serotonin secretion by platelet  (ISO)
signal transduction  (ISO)
T cell differentiation involved in immune response  (IBA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:10866110   PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FCER1G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,242,472 - 89,246,450 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,242,467 - 89,246,344 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,099,149 - 97,103,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FCER1G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,215,295 - 161,219,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,215,234 - 161,220,699 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,185,085 - 161,189,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,451,711 - 159,455,662 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,998,159 - 158,002,111NCBI
Celera1134,252,239 - 134,256,190 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,542,035 - 132,545,988 (+)NCBIHuRef
CHM1_11162,581,340 - 162,585,295 (+)NCBICHM1_1
T2T-CHM13v2.01160,352,747 - 160,356,700 (+)NCBIT2T-CHM13v2.0
Fcer1g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,057,141 - 171,061,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,057,141 - 171,061,934 (-)EnsemblGRCm39 Ensembl
GRCm381171,229,572 - 171,234,349 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,229,572 - 171,234,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,159,703 - 173,164,480 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,066,247 - 173,071,024 (-)NCBIMGSCv36mm8
Celera1173,677,711 - 173,690,567 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.23NCBI
Fcer1g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,181,908 - 86,186,766 (-)NCBIGRCr8
mRatBN7.21383,649,447 - 83,654,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,649,449 - 83,671,443 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,155,292 - 86,160,092 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,553,532 - 87,558,332 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,785,150 - 84,789,956 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,601,894 - 89,606,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,228,759 - 94,233,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,119,464 - 87,123,902 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,308,348 - 87,312,727 (-)NCBI
Celera1383,280,630 - 83,285,062 (-)NCBICelera
Cytogenetic Map13q24NCBI
Fcer1g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,971,931 - 12,975,206 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,971,931 - 12,975,206 (+)NCBIChiLan1.0ChiLan1.0
FCER1G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,632,756 - 88,636,775 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,323,067 - 88,327,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,627,672 - 136,631,696 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,539,555 - 140,543,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,539,555 - 140,544,810 (+)Ensemblpanpan1.1panPan2
FCER1G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,267,841 - 21,271,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,268,001 - 21,270,940 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,342,857 - 21,345,796 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,385,844 - 21,388,784 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,385,844 - 21,388,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03821,688,132 - 21,691,072 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,097,280 - 22,100,221 (-)NCBIUU_Cfam_GSD_1.0
Fcer1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,305,613 - 7,309,317 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903514,761 - 517,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903514,278 - 517,975 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCER1G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,763,412 - 2,767,774 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,763,417 - 2,767,248 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,811,779 - 1,815,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcer1g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794168,564 - 172,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794168,564 - 172,433 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FCER1G
69 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001001265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF148221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK230637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK230931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK343964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU606874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01103945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000006966   ⟹   ENSSSCP00000006776
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl489,242,459 - 89,247,065 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000033667   ⟹   ENSSSCP00000030545
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl489,242,472 - 89,246,450 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000078792   ⟹   ENSSSCP00000060499
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl489,242,763 - 89,246,450 (-)Ensembl
RefSeq Acc Id: NM_001001265   ⟹   NP_001001265
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1489,242,467 - 89,246,344 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001001265   ⟸   NM_001001265
- Peptide Label: precursor
- UniProtKB: Q9XSZ6 (UniProtKB/Swiss-Prot),   A0A5G2QAS1 (UniProtKB/TrEMBL),   A0A8D0WAE0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000060499   ⟸   ENSSSCT00000078792
Ensembl Acc Id: ENSSSCP00000006776   ⟸   ENSSSCT00000006966
Ensembl Acc Id: ENSSSCP00000030545   ⟸   ENSSSCT00000033667
Protein Domains
ITAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006357 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015047489 UniProtKB/TrEMBL
  ENSSSCG00025004765 UniProtKB/TrEMBL
  ENSSSCG00030027506 UniProtKB/TrEMBL
  ENSSSCG00035071417 UniProtKB/TrEMBL
  ENSSSCG00040055199 UniProtKB/TrEMBL
  ENSSSCG00045031706 UniProtKB/TrEMBL
  ENSSSCG00050029159 UniProtKB/TrEMBL
  ENSSSCG00055001920 UniProtKB/TrEMBL
  ENSSSCG00060046856 UniProtKB/TrEMBL
  ENSSSCG00065024520 UniProtKB/TrEMBL
  ENSSSCG00070025990 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000033667 ENTREZGENE
  ENSSSCT00000033667.3 UniProtKB/TrEMBL
  ENSSSCT00000033667.4 UniProtKB/Swiss-Prot
  ENSSSCT00000078792.1 UniProtKB/TrEMBL
  ENSSSCT00015063465.1 UniProtKB/TrEMBL
  ENSSSCT00015063555.1 UniProtKB/TrEMBL
  ENSSSCT00025006462.1 UniProtKB/TrEMBL
  ENSSSCT00025006464.1 UniProtKB/TrEMBL
  ENSSSCT00030038467.1 UniProtKB/TrEMBL
  ENSSSCT00030038473.1 UniProtKB/TrEMBL
  ENSSSCT00035096575.1 UniProtKB/TrEMBL
  ENSSSCT00035096581.1 UniProtKB/TrEMBL
  ENSSSCT00040074772.1 UniProtKB/TrEMBL
  ENSSSCT00040074803.1 UniProtKB/TrEMBL
  ENSSSCT00045054156.1 UniProtKB/TrEMBL
  ENSSSCT00045054198.1 UniProtKB/TrEMBL
  ENSSSCT00050039198.1 UniProtKB/TrEMBL
  ENSSSCT00050039200.1 UniProtKB/TrEMBL
  ENSSSCT00055003570.1 UniProtKB/TrEMBL
  ENSSSCT00055003577.1 UniProtKB/TrEMBL
  ENSSSCT00060063633.1 UniProtKB/TrEMBL
  ENSSSCT00060063642.1 UniProtKB/TrEMBL
  ENSSSCT00065032755.1 UniProtKB/TrEMBL
  ENSSSCT00065032760.1 UniProtKB/TrEMBL
  ENSSSCT00070052011.1 UniProtKB/TrEMBL
  ENSSSCT00070052023.1 UniProtKB/Swiss-Prot
InterPro CD3_zeta/IgE_Fc_rcpt_gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FCER1G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phos_immunorcpt_sig_ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397406 UniProtKB/Swiss-Prot
NCBI Gene FCER1G ENTREZGENE
PANTHER HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16803 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCR_zetazeta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ITAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1VQB8_PIG UniProtKB/TrEMBL
  A0A5G2QAS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WAE0 ENTREZGENE, UniProtKB/TrEMBL
  FCERG_PIG UniProtKB/Swiss-Prot
  K7GRL7_PIG UniProtKB/TrEMBL
  Q9XSZ6 ENTREZGENE
UniProt Secondary A0A8D0HVJ0 UniProtKB/TrEMBL
VGNC ID VGNC:88061 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-08 FCER1G  Fc epsilon receptor Ig  FCER1G  Fc fragment of IgE receptor Ig  Symbol and/or name change 19259463 PROVISIONAL