FCER1G (Fc epsilon receptor Ig) - Rat Genome Database

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Gene: FCER1G (Fc epsilon receptor Ig) Pan paniscus
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Symbol: FCER1G
Name: Fc epsilon receptor Ig (Ensembl:Fc fragment of IgE receptor Ig)
RGD ID: 11704552
Description: ENCODES a protein that exhibits identical protein binding (ortholog); IgE binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); drug allergy (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell surface (ortholog); Fc-gamma receptor III complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Fc fragment of IgE receptor Ig; high affinity immunoglobulin epsilon receptor subunit gamma
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,632,756 - 88,636,775 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,323,067 - 88,327,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,627,672 - 136,631,696 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,539,555 - 140,543,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,539,555 - 140,544,810 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antigen processing and presentation of exogenous peptide antigen via MHC class I  (IEA,ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IEA,ISO)
cell surface receptor signaling pathway  (IEA,ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
defense response to bacterium  (IEA,ISO)
Fc receptor mediated stimulatory signaling pathway  (IEA,ISO)
Fc-epsilon receptor signaling pathway  (IEA)
Fc-gamma receptor signaling pathway  (IEA,ISO)
immunoglobulin mediated immune response  (IEA,ISO)
innate immune response  (IEA,ISO)
integrin-mediated signaling pathway  (ISO)
interleukin-3-mediated signaling pathway  (ISO)
mast cell activation  (ISO)
mast cell apoptotic process  (ISO)
mast cell degranulation  (ISO)
negative regulation of mast cell apoptotic process  (ISO)
neutrophil activation involved in immune response  (IEA)
neutrophil chemotaxis  (IEA,ISO)
osteoclast differentiation  (ISO)
phagocytosis, engulfment  (ISO)
positive regulation of immune response  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of mast cell cytokine production  (ISO)
positive regulation of mast cell degranulation  (ISO)
positive regulation of phagocytosis  (IEA,ISO)
positive regulation of protein localization to cell surface  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of type I hypersensitivity  (ISO)
positive regulation of type IIa hypersensitivity  (ISO)
positive regulation of type III hypersensitivity  (ISO)
protein localization to plasma membrane  (ISO)
receptor internalization  (ISO)
regulation of immune response  (ISO)
regulation of platelet activation  (IEA)
serotonin secretion by platelet  (ISO)
signal transduction  (ISO)
T cell differentiation involved in immune response  (IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FCER1G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,632,756 - 88,636,775 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,323,067 - 88,327,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,627,672 - 136,631,696 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,539,555 - 140,543,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,539,555 - 140,544,810 (+)Ensemblpanpan1.1panPan2
FCER1G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,215,295 - 161,219,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,215,234 - 161,220,699 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,185,085 - 161,189,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,451,711 - 159,455,662 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,998,159 - 158,002,111NCBI
Celera1134,252,239 - 134,256,190 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,542,035 - 132,545,988 (+)NCBIHuRef
CHM1_11162,581,340 - 162,585,295 (+)NCBICHM1_1
T2T-CHM13v2.01160,352,747 - 160,356,700 (+)NCBIT2T-CHM13v2.0
Fcer1g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,057,141 - 171,061,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,057,141 - 171,061,934 (-)EnsemblGRCm39 Ensembl
GRCm381171,229,572 - 171,234,349 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,229,572 - 171,234,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,159,703 - 173,164,480 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,066,247 - 173,071,024 (-)NCBIMGSCv36mm8
Celera1173,677,711 - 173,690,567 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.23NCBI
Fcer1g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,181,908 - 86,186,766 (-)NCBIGRCr8
mRatBN7.21383,649,447 - 83,654,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,649,449 - 83,671,443 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,155,292 - 86,160,092 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,553,532 - 87,558,332 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,785,150 - 84,789,956 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,601,894 - 89,606,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,228,759 - 94,233,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,119,464 - 87,123,902 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,308,348 - 87,312,727 (-)NCBI
Celera1383,280,630 - 83,285,062 (-)NCBICelera
Cytogenetic Map13q24NCBI
Fcer1g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,971,931 - 12,975,206 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,971,931 - 12,975,206 (+)NCBIChiLan1.0ChiLan1.0
FCER1G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,267,841 - 21,271,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,268,001 - 21,270,940 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,342,857 - 21,345,796 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,385,844 - 21,388,784 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,385,844 - 21,388,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03821,688,132 - 21,691,072 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,097,280 - 22,100,221 (-)NCBIUU_Cfam_GSD_1.0
Fcer1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,305,613 - 7,309,317 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903514,761 - 517,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903514,278 - 517,975 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCER1G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,242,472 - 89,246,450 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,242,467 - 89,246,344 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,099,149 - 97,103,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FCER1G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,763,412 - 2,767,774 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,763,417 - 2,767,248 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,811,779 - 1,815,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcer1g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794168,564 - 172,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794168,564 - 172,433 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003811835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000029169   ⟹   ENSPPAP00000007110
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1140,539,555 - 140,543,545 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000029185   ⟹   ENSPPAP00000007118
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1140,539,633 - 140,544,810 (+)Ensembl
RefSeq Acc Id: XM_003811835   ⟹   XP_003811883
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,632,756 - 88,636,775 (-)NCBI
NHGRI_mPanPan1188,323,067 - 88,327,094 (-)NCBI
Mhudiblu_PPA_v01136,627,672 - 136,631,696 (+)NCBI
PanPan1.11140,539,555 - 140,543,545 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003811883 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000007110
  ENSPPAP00000007110.1
  ENSPPAP00000007118.1
RefSeq Acc Id: XP_003811883   ⟸   XM_003811835
- UniProtKB: A0A2R8ZQ97 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000007110   ⟸   ENSPPAT00000029169
Ensembl Acc Id: ENSPPAP00000007118   ⟸   ENSPPAT00000029185


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026233 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029169.1 UniProtKB/TrEMBL
  ENSPPAT00000029185.1 UniProtKB/TrEMBL
InterPro CD3_zeta/IgE_Fc_rcpt_gamma UniProtKB/TrEMBL
  FCER1G UniProtKB/TrEMBL
  Phos_immunorcpt_sig_ITAM UniProtKB/TrEMBL
KEGG Report pps:100978230 UniProtKB/TrEMBL
NCBI Gene FCER1G ENTREZGENE
PANTHER HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA UniProtKB/TrEMBL
  PTHR16803 UniProtKB/TrEMBL
Pfam ITAM UniProtKB/TrEMBL
  TCR_zetazeta UniProtKB/TrEMBL
PROSITE ITAM_1 UniProtKB/TrEMBL
SMART ITAM UniProtKB/TrEMBL
UniProt A0A2R8ZQ97 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZTE1_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 FCER1G  Fc epsilon receptor Ig  FCER1G  Fc fragment of IgE receptor Ig  Symbol and/or name change 5135510 APPROVED