| 1305712 | Etf1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (ortholog); sequence-specific mRNA binding (ortholog); translation release factor activity (ortholog); INVOLVED IN protein methylation (ortholog); regulation of translational termination (ortholog); translational termination (ortholog) ; PARTICIPATES IN translation termination pathway; mRNA decay pathway; FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); nucleus (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 2-methoxyethanol; 6-propyl-2-thiouracil | 18 | 26776518 | 26804857 | Rat | 136 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313906 | ETF1 | eukaryotic translation termination factor 1 | This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mR NAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013] | 5 | 138506095 | 138543236 | Human | 140 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1313907 | Etf1 | eukaryotic translation termination factor 1 | Predicted to enable peptidyl-tRNA hydrolase activity; sequence-specific mRNA binding activity; and translation release factor activity, codon specific. Predicted to be involved in cytoplasmic translational termination and regulation of translational termination. Predicted to act upstream of or withi n protein methylation. Predicted to be located in cytoplasm. Predicted to be part of translation release factor complex. Predicted to be active in cytosolic ribosome. Is expressed in central nervous system; early embryo; and retina. Orthologous to human ETF1 (eukaryotic translation termination factor 1). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 35035838 | 35065060 | Mouse | 147 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8982705 | Etf1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (ortholog); sequence-specific mRNA binding (ortholog); translation release factor activity (ortholog); INVOLVED IN protein methylation (ortholog); regulation of translational termination (ortholog); translational termination (ortholog) ; PARTICIPATES IN translation termination pathway; FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); nucleus (ortholog) | NW_004955418 | 1943233 | 1974241 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11974084 | ETF1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (inferred); sequence-specific mRNA binding (inferred); translation release factor activity (inferred); INVOLVED IN protein methylation (ortholog); translational termination (ortholog); PARTICIPATES IN translation termination pathway; F OUND IN nucleus (ortholog) | 5 | 133886074 | 133922682 | Bonobo | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12361415 | ETF1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (inferred); sequence-specific mRNA binding (inferred); translation release factor activity (inferred); INVOLVED IN protein methylation (ortholog); translational termination (ortholog); PARTICIPATES IN translation termination pathway; F OUND IN nucleus (ortholog) | 11 | 26078611 | 26110805 | Dog | 30 | symbol | gene, protein-coding, INFERRED [RefSeq] |
| 12558347 | Etf1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (inferred); sequence-specific mRNA binding (inferred); translation release factor activity (inferred); INVOLVED IN protein methylation (ortholog); translational termination (ortholog); PARTICIPATES IN translation termination pathway; F OUND IN nucleus (ortholog) | NW_004936531 | 7665246 | 7693563 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14168296 | ETF1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (inferred); sequence-specific mRNA binding (inferred); translation release factor activity (inferred); INVOLVED IN protein methylation (ortholog); translational termination (ortholog); PARTICIPATES IN translation termination pathway; F OUND IN nucleus (ortholog) | | | | Pig | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18444268 | ETF1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (ortholog); sequence-specific mRNA binding (ortholog); translation release factor activity (ortholog); INVOLVED IN protein methylation (ortholog); regulation of translational termination (ortholog); translational termination (ortholog) ; PARTICIPATES IN translation termination pathway; FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); nucleus (ortholog) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902115 | Etf1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (ortholog); sequence-specific mRNA binding (ortholog); translation termination factor activity (ortholog); INVOLVED IN protein methylation (ortholog); regulation of translational termination (ortholog); translational termination (ortho log); PARTICIPATES IN translation termination pathway; FOUND IN cytosolic ribosome (ortholog); nucleus (ortholog); translation release factor complex (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246581 | etf1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626023106 | Etf1 | eukaryotic translation termination factor 1 | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (ortholog); sequence-specific mRNA binding (ortholog); translation release factor activity (ortholog); INVOLVED IN protein methylation (ortholog); regulation of translational termination (ortholog); translational termination (ortholog) ; PARTICIPATES IN translation termination pathway; FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); nucleus (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255158 | etf1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1583766 | Etf1-ps1 | eukaryotic translation termination factor 1, pseudogene 1 | | X | 66346871 | 66348333 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1582848 | Etf1-ps2 | eukaryotic translation termination factor 1, pseudogene 2 | | 1 | 101799613 | 101805340 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1597217 | Etf1-ps3 | eukaryotic translation termination factor 1, pseudogene 3 | | 15 | 34000843 | 34002428 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 16559281 | AC104136.1 | eukaryotic translation termination factor 1 (ETF1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1311843 | Hemk2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits arsenite methyltransferase activity (ortholog); histone H4K12 methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); methylation (ortholog); negative regulation of gene expression, epigenetic (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 11 | 40071017 | 40083463 | Rat | 98 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1323512 | HEMK2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid . Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Mar 2023] | 21 | 28575598 | 28885367 | Human | 99 | name | gene, protein-coding, REVIEWED [RefSeq] |
| 8720686 | Hemk2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits arsenite methyltransferase activity (ortholog); histone H4K12 methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); methylation (ortholog); negative regulation of gene expression, epigenetic (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog) | NW_004955407 | 28256654 | 28277514 | Chinchilla | 22 | name | gene, protein-coding, MODEL [RefSeq] |
| 11784888 | HEMK2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits site-specific DNA-methyltransferase (adenine-specific) activity (ortholog); INVOLVED IN peptidyl-glutamine methylation (ortholog); positive regulation of cell growth (ortholog); FOUND IN cytoplasm (inferred); eRF1 methyltransferase complex (inferred); nucleus (inferre d) | 21 | 15303430 | 15316596 | Bonobo | 31 | name | gene, protein-coding, MODEL [RefSeq] |
| 12536039 | Hemk2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits site-specific DNA-methyltransferase (adenine-specific) activity (ortholog); INVOLVED IN peptidyl-glutamine methylation (ortholog); positive regulation of cell growth (ortholog); FOUND IN cytoplasm (inferred); eRF1 methyltransferase complex (inferred); nucleus (inferre d) | NW_004936500 | 13086873 | 13099814 | Squirrel | 31 | name | gene, protein-coding, MODEL [RefSeq] |
| 18753830 | HEMK2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits site-specific DNA-methyltransferase (adenine-specific) activity (ortholog); INVOLVED IN peptidyl-glutamine methylation (ortholog); positive regulation of cell growth (ortholog); FOUND IN cytoplasm (inferred); eRF1 methyltransferase complex (inferred); nucleus (inferre d) | | | | Green Monkey | 31 | name | gene, protein-coding, MODEL [RefSeq] |
| 18908887 | Hemk2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits arsenite methyltransferase activity (ortholog); histone H4K12 methyltransferase activity (ortholog); S-adenosyl-L-methionine binding (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); negative regulation of gene expression, epigenetic (ortholog); pept idyl-glutamine methylation (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog) | | | | Naked Mole-Rat | 27 | name | gene, protein-coding, MODEL [RefSeq] |
| 626154648 | Hemk2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits arsenite methyltransferase activity (ortholog); histone H4K12 methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); methylation (ortholog); negative regulation of gene expression, epigenetic (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog) | | | | Black Rat | 22 | name | gene, protein-coding, MODEL [RefSeq] |
| 38610930 | LOC642897 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine pseudogene | | 11 | 93609432 | 93610414 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 1351224 | ETF1P1 | eukaryotic translation termination factor 1 pseudogene 1 | INTERACTS WITH cadmium dichloride | 6 | 30031713 | 30033877 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1345726 | ETF1P2 | eukaryotic translation termination factor 1 pseudogene 2 | | 7 | 151501762 | 151504327 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1343202 | ETF1P3 | eukaryotic translation termination factor 1 pseudogene 3 | | X | 65794345 | 65798029 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |