| 2538 | Eef2k | eukaryotic elongation factor-2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity; calmodulin binding (ortholog); INVOLVED IN cellular response to anoxia; cellular response to brain-derived neurotrophic factor stimulus; cellular response to calcium ion; PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Alzh eimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine; glutamatergic synapse; postsynaptic density; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol | 1 | 184824420 | 184888048 | Rat | 210 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10506 | Eef2k | eukaryotic elongation factor-2 kinase | Enables calmodulin binding activity and elongation factor-2 kinase activity. Involved in regulation of protein autophosphorylation. Predicted to be located in dendritic spine. Predicted to be active in glutamatergic synapse and postsynaptic density. Is expressed in liver; lung; nervous system; and o lfactory epithelium. Orthologous to human EEF2K (eukaryotic elongation factor 2 kinase). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 120442080 | 120506441 | Mouse | 235 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1351780 | EEF2K | eukaryotic elongation factor 2 kinase | This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008] | 16 | 22206278 | 22288738 | Human | 213 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8847357 | Eef2k | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits calmodulin binding (ortholog); elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog) | NW_004955493 | 865830 | 922765 | Chinchilla | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11834130 | EEF2K | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIA TED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog) | 16 | 16443579 | 16526061 | Bonobo | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12125427 | EEF2K | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIA TED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH bisphenol A | 6 | 23368296 | 23433853 | Dog | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12517187 | Eef2k | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIA TED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog) | NW_004936501 | 7160134 | 7205231 | Squirrel | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14140309 | EEF2K | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIA TED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog) | | | | Pig | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18386687 | EEF2K | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIA TED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog) | | | | Green Monkey | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922453 | Eef2k | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIA TED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog) | | | | Naked Mole-Rat | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256292 | eef2k | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625886602 | Eef2k | eukaryotic elongation factor 2 kinase | ENCODES a protein that exhibits calmodulin binding (ortholog); elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); lung adenocarcinoma (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog) | | | | Black Rat | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259259 | eef2k.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862278 | eef2k.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863210 | eef2k.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863700 | eef2k.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865303 | eef2k.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468193 | eef2k.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469353 | eef2k.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6496985 | Eef2k-ps1 | eukaryotic elongation factor-2 kinase, pseudogene 1 | | 13 | 29390400 | 29392288 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 16563104 | AC009034.1 | novel transcript, antisense to EEF2K | | | | | Human | | name | gene, lncrna |
| 1304969 | Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 10 | 10843429 | 10853800 | Rat | 54 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1603258 | EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation. Located in cytoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 5084284 | 5097795 | Human | 61 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1621515 | Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase | Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine trimethylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Orthologous to several human genes including EEF2K an>MT (eukaryotic elongation factor 2 lysine methyltransferase). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 5062019 | 5073820 | Mouse | 62 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8728640 | Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog) | NW_004955442 | 12467077 | 12475902 | Chinchilla | 8 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11901286 | EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits methyltransferase activity (inferred); protein-lysine N-methyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (inferred); protein-containing complex (inferred) | 16 | 4009227 | 4014944 | Bonobo | 13 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12391237 | EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits methyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog) | 6 | 36353626 | 36370466 | Dog | 12 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12587131 | Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog) | NW_004936530 | 4957445 | 4984816 | Squirrel | 12 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14039946 | EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits methyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog) | | | | Pig | 12 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18428713 | EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog) | | | | Green Monkey | 12 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18905038 | Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog) | | | | Naked Mole-Rat | 13 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155235570 | eef2kmt | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625954471 | Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase | ENCODES a protein that exhibits protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine trimethylation (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog) | | | | Black Rat | 8 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155242784 | eef2kmt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 11847415 | LOC100976782 | protein-lysine N-methyltransferase EEF2KMT | | 4 | 4094938 | 4127069 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11716679 | LOC100977958 | protein-lysine N-methyltransferase EEF2KMT-like | | 7 | 7695750 | 7705241 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11669621 | LOC100988971 | protein-lysine N-methyltransferase EEF2KMT-like | | | | | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11720426 | LOC100989933 | protein-lysine N-methyltransferase EEF2KMT-like | | | | | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11808291 | LOC100996191 | protein-lysine N-methyltransferase EEF2KMT-like | | 12 | 8355554 | 8365322 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 32729153 | LOC117978000 | protein-lysine N-methyltransferase EEF2KMT-like | | | | | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 32730535 | LOC117979691 | protein-lysine N-methyltransferase EEF2KMT-like | | 3 | 75361422 | 75373906 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 32730016 | LOC117979748 | protein-lysine N-methyltransferase EEF2KMT-like | | 3 | 122990645 | 122996332 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 32728244 | LOC117979762 | protein-lysine N-methyltransferase EEF2KMT-like | | 3 | 127178984 | 127185585 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 32732301 | LOC117981336 | protein-lysine N-methyltransferase EEF2KMT-like | | 8 | 11472529 | 11485080 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 329344776 | LOC129398565 | protein-lysine N-methyltransferase EEF2KMT-like | | | | | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 329346773 | LOC129398591 | protein-lysine N-methyltransferase EEF2KMT-like | | | | | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 12046697 | FAM86C1P | family with sequence similarity 86 member C1 | ENCODES a protein that exhibits methyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN methylation (inferred); FOUND IN protein-containing complex (ortholog) | 7 | 7650245 | 7656291 | Bonobo | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 6766389 | FAM86KP | family with sequence similarity 86 member K, pseudogene | | 4 | 9153215 | 9166878 | Human | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 32730267 | LOC117978151 | uncharacterized LOC117978151 | | | | | Bonobo | | old_gene_name | gene, ncrna, MODEL [RefSeq] |
| 329845678 | LOC128966622 | putative protein N-methyltransferase FAM86B2 | ENCODES a protein that exhibits methyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN methylation (inferred) | | | | Human | 3 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |