EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase) - Rat Genome Database

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Gene: EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase) Pan paniscus
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Symbol: EEF2KMT
Name: eukaryotic elongation factor 2 lysine methyltransferase
RGD ID: 11901286
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); protein-lysine N-methyltransferase activity (inferred); INVOLVED IN peptidyl-lysine trimethylation (ortholog); ASSOCIATED WITH congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation Ik (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM86A; family with sequence similarity 86, member A; LOC100988451; protein-lysine N-methyltransferase EEF2KMT; uncharacterized LOC100988451; uncharacterized protein LOC100988451
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2185,613,290 - 5,625,864 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1169,403,868 - 9,416,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0164,009,227 - 4,014,944 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1165,172,663 - 5,277,224 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl165,173,979 - 5,191,174 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EEF2KMT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2185,613,290 - 5,625,864 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1169,403,868 - 9,416,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0164,009,227 - 4,014,944 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1165,172,663 - 5,277,224 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl165,173,979 - 5,191,174 (-)Ensemblpanpan1.1panPan2
EEF2KMT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38165,084,284 - 5,097,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl165,084,284 - 5,097,795 (-)EnsemblGRCh38hg38GRCh38
GRCh37165,134,285 - 5,147,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36165,075,236 - 5,087,782 (-)NCBINCBI36Build 36hg18NCBI36
Celera165,343,693 - 5,357,187 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef165,100,367 - 5,113,916 (-)NCBIHuRef
CHM1_1165,135,491 - 5,148,985 (-)NCBICHM1_1
T2T-CHM13v2.0165,113,786 - 5,127,302 (-)NCBIT2T-CHM13v2.0
Eef2kmt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39165,062,019 - 5,073,820 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl165,062,016 - 5,073,847 (-)EnsemblGRCm39 Ensembl
GRCm38165,244,155 - 5,255,956 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl165,244,152 - 5,255,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv37165,244,248 - 5,256,049 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36165,159,476 - 5,171,277 (-)NCBIMGSCv36mm8
Celera165,877,168 - 5,888,966 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.51NCBI
Eef2kmt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81010,843,429 - 10,853,800 (+)NCBIGRCr8
mRatBN7.21010,336,933 - 10,349,463 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1010,336,974 - 10,347,039 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,043,627 - 15,053,683 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01014,532,428 - 14,542,490 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,201,418 - 10,211,484 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01010,530,302 - 10,540,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1010,530,365 - 10,540,428 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,300,149 - 9,310,577 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,450,534 - 10,460,596 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11010,450,554 - 10,460,124 (+)NCBI
Celera109,303,038 - 9,313,101 (+)NCBICelera
Cytogenetic Map10q12NCBI
Eef2kmt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544212,467,077 - 12,475,902 (+)NCBIChiLan1.0ChiLan1.0
EEF2KMT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1636,353,626 - 36,370,466 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha637,744,735 - 37,763,681 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0636,554,792 - 36,573,955 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1636,353,667 - 36,372,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,244,755 - 36,263,844 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0636,644,889 - 36,664,041 (+)NCBIUU_Cfam_GSD_1.0
Eef2kmt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344107,111,725 - 107,120,621 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365304,957,445 - 4,984,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EEF2KMT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1337,310,915 - 37,324,705 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,315,814 - 38,330,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EEF2KMT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,752,247 - 4,768,240 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606825,889,562 - 25,902,921 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eef2kmt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248242,875,590 - 2,884,687 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000052279   ⟹   ENSPPAP00000029430
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl165,173,979 - 5,191,174 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000052280   ⟹   ENSPPAP00000029431
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl165,173,979 - 5,188,397 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000052281   ⟹   ENSPPAP00000029432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl165,173,979 - 5,188,397 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000052283   ⟹   ENSPPAP00000029434
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl165,173,979 - 5,188,397 (-)Ensembl
RefSeq Acc Id: XM_055099912   ⟹   XP_054955887
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2185,613,290 - 5,625,756 (-)NCBI
NHGRI_mPanPan1169,403,868 - 9,416,642 (-)NCBI
RefSeq Acc Id: XM_055099913   ⟹   XP_054955888
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2185,613,290 - 5,625,864 (-)NCBI
NHGRI_mPanPan1169,403,868 - 9,416,646 (-)NCBI
RefSeq Acc Id: XM_055099914   ⟹   XP_054955889
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2185,613,290 - 5,625,864 (-)NCBI
NHGRI_mPanPan1169,403,868 - 9,416,645 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054955887 (Get FASTA)   NCBI Sequence Viewer  
  XP_054955888 (Get FASTA)   NCBI Sequence Viewer  
  XP_054955889 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000029430.1
  ENSPPAP00000029431.1
  ENSPPAP00000029432.1
  ENSPPAP00000029434.1
Ensembl Acc Id: ENSPPAP00000029430   ⟸   ENSPPAT00000052279
Ensembl Acc Id: ENSPPAP00000029434   ⟸   ENSPPAT00000052283
Ensembl Acc Id: ENSPPAP00000029432   ⟸   ENSPPAT00000052281
Ensembl Acc Id: ENSPPAP00000029431   ⟸   ENSPPAT00000052280
RefSeq Acc Id: XP_054955888   ⟸   XM_055099913
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BS69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054955889   ⟸   XM_055099914
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BLX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054955887   ⟸   XM_055099912
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BS69 (UniProtKB/TrEMBL)
Protein Domains
FAM86 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037714 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052279.1 UniProtKB/TrEMBL
  ENSPPAT00000052280.1 UniProtKB/TrEMBL
  ENSPPAT00000052281.1 UniProtKB/TrEMBL
  ENSPPAT00000052283.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro FAM86_N UniProtKB/TrEMBL
  Methyltransf_16 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene EEF2KMT ENTREZGENE
PANTHER PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT-RELATED UniProtKB/TrEMBL
  PTHR14614 UniProtKB/TrEMBL
Pfam FAM86 UniProtKB/TrEMBL
  Methyltransf_16 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A2R9BIE2_PANPA UniProtKB/TrEMBL
  A0A2R9BIF5_PANPA UniProtKB/TrEMBL
  A0A2R9BLX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BS69 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-11 EEF2KMT  eukaryotic elongation factor 2 lysine methyltransferase  LOC100988451  uncharacterized LOC100988451  Data merged from RGD:11887324 737654 PROVISIONAL