| 14376013 | Dci | | | | | | Fly | | symbol | gene, null |
| 1617594 | Clec4a2 | C-type lectin domain family 4, member a2 | Predicted to enable D-mannose binding activity; calcium ion binding activity; and pattern recognition receptor activity. Predicted to be involved in several processes, including antifungal innate immune response; negative regulation of tumor necrosis factor production; and plasmacytoid dendritic cel l antigen processing and presentation. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4A (C-type lectin domain family 4 member A). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 123099627 | 123119891 | Mouse | 72 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1616349 | Clec4a4 | C-type lectin domain family 4, member a4 | Enables carbohydrate derivative binding activity. Predicted to be involved in several processes, including antifungal innate immune response; negative regulation of tumor necrosis factor production; and plasmacytoid dendritic cell antigen processing and presentation. Predicted to be active in extern al side of plasma membrane. Is expressed in ductus deferens; epididymis; and prostate gland. Orthologous to human CLEC4A (C-type lectin domain family 4 member A). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 122967326 | 123001380 | Mouse | 23 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1614055 | Cxcl3 | C-X-C motif chemokine ligand 3 | This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C mot if) receptor 2 to recruit neutrophils. [provided by RefSeq, May 2013] | 5 | 90933960 | 90935952 | Mouse | 629 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 61892 | Eci1 | enoyl-CoA delta isomerase 1 | ENCODES a protein that exhibits delta(3)-delta(2)-enoyl-CoA isomerase activity; identical protein binding; intramolecular oxidoreductase activity, transposing C=C bonds; INVOLVED IN fatty acid beta-oxidation; FOUND IN mitochondrion; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8- tetrachlorodibenzodioxine | 10 | 13961250 | 13974595 | Rat | 212 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62185 | Eci1 | enoyl-Coenzyme A delta isomerase 1 | Enables delta(3)-delta(2)-enoyl-CoA isomerase activity. Acts upstream of or within fatty acid beta-oxidation. Located in mitochondrial inner membrane. Is expressed in cerebral cortex and testis. Orthologous to human ECI1 (enoyl-CoA delta isomerase 1). [provided by Alliance of Genome Resources, Jul 2 025] | 17 | 24645657 | 24658290 | Mouse | 218 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1352961 | ECI1 | enoyl-CoA delta isomerase 1 | This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, an d polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] | 16 | 2239402 | 2251587 | Human | 212 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 12213145 | ECI1 | enoyl-CoA delta isomerase 1 | ENCODES a protein that exhibits delta(3)-delta(2)-enoyl-CoA isomerase activity (ortholog); identical protein binding (ortholog); intramolecular oxidoreductase activity, transposing C=C bonds (ortholog); INVOLVED IN fatty acid beta-oxidation (ortholog); FOUND IN mitochondrial matrix (inferred); mitoc hondrion (inferred) | 6 | 38729729 | 38738357 | Dog | 14 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14175185 | ECI1 | enoyl-CoA delta isomerase 1 | ENCODES a protein that exhibits delta(3)-delta(2)-enoyl-CoA isomerase activity (ortholog); identical protein binding (ortholog); intramolecular oxidoreductase activity, transposing C=C bonds (ortholog); INVOLVED IN fatty acid beta-oxidation (ortholog); FOUND IN mitochondrial matrix (inferred); mitoc hondrion (inferred) | | | | Pig | 15 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 16563384 | ECI1-AS1 | ECI1 antisense RNA 1 | | | | | Human | | old_gene_name | gene, lncrna |
| 14370939 | DCI1 | | | | | | Yeast | | symbol | gene, null |
| 1352867 | CLEC4A | C-type lectin domain family 4 member A | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The enco ded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] | 12 | 8102907 | 8138607 | Human | 115 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1618839 | Clec4a1 | C-type lectin domain family 4, member a1 | Predicted to enable D-mannose binding activity; calcium ion binding activity; and pattern recognition receptor activity. Predicted to be involved in antifungal innate immune response. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4A (C-type lectin domain family 4 member A). [provided by Alliance of Genome Resources, Apr 2025] | 6 | 122898807 | 122911578 | Mouse | 82 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1550790 | Clec4a3 | C-type lectin domain family 4, member a3 | Predicted to enable D-mannose binding activity; calcium ion binding activity; and pattern recognition receptor activity. Predicted to be involved in several processes, including antifungal innate immune response; negative regulation of tumor necrosis factor production; and plasmacytoid dendritic cel l antigen processing and presentation. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4A (C-type lectin domain family 4 member A). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 122929474 | 122946837 | Mouse | 113 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1318099 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndr ome. [provided by RefSeq, Mar 2010] | 20 | 36889773 | 36951708 | Human | 395 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1359662 | Clec4a | C-type lectin domain family 4, member A | ENCODES a protein that exhibits calcium ion binding (ortholog); carbohydrate binding (ortholog); D-mannose binding (ortholog); INVOLVED IN antifungal innate immune response (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); CD8-positive, alpha-be ta T cell activation (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH (1->4)-beta-D-glucan (ortholog); 1,1-dichloroethene (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 4 | 158026138 | 158119904 | Rat | 77 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359109 | Clec4a1 | C-type lectin domain family 4, member A1 | ENCODES a protein that exhibits carbohydrate binding (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol | 4 | 157845811 | 157857926 | Rat | 61 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359163 | Clec4a2 | C-type lectin domain family 4, member A2 | ENCODES a protein that exhibits carbohydrate binding (inferred); metal ion binding (inferred); INVOLVED IN adaptive immune response (inferred); immune system process (inferred); innate immune response (inferred); FOUND IN plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 157934342 | 157993595 | Rat | 19 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359528 | Clec4a3 | C-type lectin domain family 4, member A3 | ENCODES a protein that exhibits calcium ion binding (ortholog); carbohydrate binding (ortholog); D-mannose binding (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); CD8-positive, alpha-beta T cell activation (ortholog); negative regu lation of cytokine production (ortholog); ASSOCIATED WITH allergic disease (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 4 | 157885899 | 157896728 | Rat | 111 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1602051 | CXCL17 | C-X-C motif chemokine ligand 17 | The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Sa lmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015] | 19 | 42428278 | 42442946 | Human | 81 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 732077 | PSMC3 | proteasome 26S subunit, ATPase 3 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. T he 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008] | 11 | 47418775 | 47426439 | Human | 209 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 69198 | Rcan2 | regulator of calcineurin 2 | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN calcineurin-NFAT signaling cascade (ortholog); locomotion involved in locomotory behavior (ortholog); Notch signaling pathway (ortholog); ASSOCIATED WITH metabolic dysfunction-associated steatotic liver disease (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4,6-trinitrotoluene | 9 | 24456861 | 24674234 | Rat | 153 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
