ECI1 (enoyl-CoA delta isomerase 1) - Rat Genome Database

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Gene: ECI1 (enoyl-CoA delta isomerase 1) Canis lupus familiaris
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Symbol: ECI1
Name: enoyl-CoA delta isomerase 1
RGD ID: 12213145
Description: ENCODES a protein that exhibits delta(3)-delta(2)-enoyl-CoA isomerase activity (ortholog); identical protein binding (ortholog); intramolecular oxidoreductase activity, transposing C=C bonds (ortholog); INVOLVED IN fatty acid beta-oxidation (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 1 (ortholog); endometrial carcinoma (ortholog); epilepsy (ortholog); FOUND IN mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3,2-trans-enoyl-CoA isomerase, mitochondrial; DCI; dodecenoyl-CoA isomerase; dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase); enoyl-CoA delta isomerase 1, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,729,729 - 38,738,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,730,219 - 38,738,219 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,969,905 - 39,977,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,039,094 - 39,047,029 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,039,030 - 39,046,867 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,724,133 - 38,732,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,695,920 - 38,704,312 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,175,160 - 39,183,085 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ECI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,729,729 - 38,738,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,730,219 - 38,738,219 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,969,905 - 39,977,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,039,094 - 39,047,029 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,039,030 - 39,046,867 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,724,133 - 38,732,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,695,920 - 38,704,312 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,175,160 - 39,183,085 (+)NCBIUU_Cfam_GSD_1.0
ECI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,239,402 - 2,251,587 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,239,402 - 2,252,300 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,289,403 - 2,301,588 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,229,897 - 2,241,604 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,229,898 - 2,241,576NCBI
Celera162,504,294 - 2,516,030 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,215,959 - 2,227,648 (-)NCBIHuRef
CHM1_1162,289,822 - 2,301,559 (-)NCBICHM1_1
T2T-CHM13v2.0162,261,850 - 2,274,034 (-)NCBIT2T-CHM13v2.0
Eci1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,645,657 - 24,658,290 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,645,615 - 24,658,322 (+)EnsemblGRCm39 Ensembl
GRCm381724,426,683 - 24,439,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,426,641 - 24,439,348 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,563,628 - 24,576,261 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,154,283 - 24,166,914 (+)NCBIMGSCv36mm8
Celera1724,939,193 - 24,953,366 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.39NCBI
Eci1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,961,250 - 13,974,595 (+)NCBIGRCr8
mRatBN7.21013,456,715 - 13,470,061 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,456,563 - 13,470,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,203,212 - 18,216,533 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,692,057 - 17,705,378 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,191,242 - 13,204,563 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,797,573 - 13,810,918 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,797,562 - 13,810,913 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,614,559 - 13,627,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,683,000 - 13,697,179 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,682,988 - 13,697,174 (+)NCBI
Celera1013,137,220 - 13,150,564 (+)NCBICelera
Cytogenetic Map10q12NCBI
Eci1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,010,412 - 15,027,014 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,010,412 - 15,027,014 (+)NCBIChiLan1.0ChiLan1.0
ECI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,741,784 - 2,753,362 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,522,684 - 6,534,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,097,165 - 1,108,726 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,339,864 - 2,351,221 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,339,864 - 2,351,385 (-)Ensemblpanpan1.1panPan2
Eci1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,902,157 - 104,914,806 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,794,670 - 1,807,299 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,794,673 - 1,807,306 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,750,742 - 39,758,516 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,750,742 - 39,758,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,422,314 - 42,425,576 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,135,042 - 2,147,246 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,135,129 - 2,147,109 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,910,452 - 28,924,540 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eci1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462482453,458 - 66,946 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462482453,174 - 66,986 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ECI1
97 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 4 5 21 6 3 6 6 6 11 10 6
Below cutoff 1 1 3 1 8

Sequence


RefSeq Acc Id: ENSCAFT00000048077   ⟹   ENSCAFP00000041497
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,730,219 - 38,738,219 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845008131   ⟹   ENSCAFP00845006385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl639,039,030 - 39,046,281 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845008141   ⟹   ENSCAFP00845006394
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl639,039,094 - 39,046,867 (+)Ensembl
RefSeq Acc Id: XM_038480359   ⟹   XP_038336287
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1638,724,133 - 38,732,054 (+)NCBI
RefSeq Acc Id: XM_038535285   ⟹   XP_038391213
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha639,969,905 - 39,977,831 (+)NCBI
RefSeq Acc Id: XM_038538935   ⟹   XP_038394863
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0639,175,160 - 39,183,085 (+)NCBI
RefSeq Acc Id: XM_038602950   ⟹   XP_038458878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0638,695,920 - 38,704,312 (+)NCBI
RefSeq Acc Id: XM_038667650   ⟹   XP_038523578
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0639,039,094 - 39,047,029 (+)NCBI
RefSeq Acc Id: ENSCAFP00000041497   ⟸   ENSCAFT00000048077
RefSeq Acc Id: XP_038336287   ⟸   XM_038480359
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458878   ⟸   XM_038602950
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038523578   ⟸   XM_038667650
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R8A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391213   ⟸   XM_038535285
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R8A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394863   ⟸   XM_038538935
- Peptide Label: isoform X3
- UniProtKB: A0A8C0R8A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845006394   ⟸   ENSCAFT00845008141
RefSeq Acc Id: ENSCAFP00845006385   ⟸   ENSCAFT00845008131

Promoters
RGD ID:13683729
Promoter ID:EPDNEW_C1797
Type:initiation region
Name:ECI1_1
Description:enoyl-CoA delta isomerase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1638,730,582 - 38,730,642EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030058 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845004550 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048077.3 UniProtKB/TrEMBL
  ENSCAFT00000096163.1 UniProtKB/TrEMBL
  ENSCAFT00845008131.1 UniProtKB/TrEMBL
  ENSCAFT00845008141 ENTREZGENE
  ENSCAFT00845008141.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.170 UniProtKB/TrEMBL
InterPro ClpP/crotonase-like_dom_sf UniProtKB/TrEMBL
  Enoyl-CoA_hydra/iso UniProtKB/TrEMBL
NCBI Gene ECI1 ENTREZGENE
PANTHER ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL UniProtKB/TrEMBL
  ENOYL-COA HYDRATASE-RELATED UniProtKB/TrEMBL
Pfam ECH_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF52096 UniProtKB/TrEMBL
UniProt A0A8C0R8A2 ENTREZGENE
  A0A8I3MN34_CANLF UniProtKB/TrEMBL
  A0A8I3MWV6_CANLF UniProtKB/TrEMBL
  A0A8P0NSD6_CANLF UniProtKB/TrEMBL
  A0A8P0TI23_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:54017 ENTREZGENE