| 620507 | Crnkl1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus; cellular response to leukemia inhibitory factor; cerebral cortex development; PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); FOU ND IN catalytic step 2 spliceosome (ortholog); nucleus (ortholog); spliceosomal complex (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,4-dinitrotoluene | 3 | 153764718 | 153807973 | Rat | 84 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733946 | CRNKL1 | crooked neck pre-mRNA splicing factor 1 | The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicin g. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013] | 20 | 20034368 | 20056046 | Human | 82 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1550317 | Crnkl1 | crooked neck pre-mRNA splicing factor 1 | Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Is expressed in several structures, includ ing central nervous system and sensory organ. Human ortholog(s) of this gene implicated in basal cell carcinoma. Orthologous to human CRNKL1 (crooked neck pre-mRNA splicing factor 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 145759402 | 145776620 | Mouse | 96 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8724933 | Crnkl1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleus (ortholog); post-mRNA release spliceosomal complex (ortholog) | NW_004955415 | 28158351 | 28171335 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11909487 | CRNKL1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | 20 | 19992092 | 20010809 | Bonobo | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12269138 | CRNKL1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | 24 | 3294607 | 3310846 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12475083 | Crnkl1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | NW_004936485 | 328077 | 351323 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625842034 | Crnkl1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleus (ortholog); post-mRNA release spliceosomal complex (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13977158 | CRNKL1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241317 | crnkl1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18541885 | CRNKL1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Green Monkey | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936214 | Crnkl1 | crooked neck pre-mRNA splicing factor 1 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH bas al cell carcinoma (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleus (ortholog); post-spliceosomal complex (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 596936059 | crnkl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247665 | crnkl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934164 | crnkl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934410 | crnkl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596935284 | crnkl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241316 | crnkl1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7242712 | Crnkl1-ps1 | crooked neck pre-mRNA splicing factor 1, pseudogene 1 | | 6 | 6894293 | 6896607 | Rat | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 7696302 | LOC102548514 | crooked neck-like protein 1-like | INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA processing (inferred); FOUND IN nucleus (inferred); spliceosomal complex (inferred) | | | | Rat | 6 | ensembl_gene_symbol | gene, protein-coding |