| 1306794 | Chd1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits histone H3K4me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); host-mediated activation of viral transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (ortholog); nuclear chromosome (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 65334905 | 65402270 | Rat | 129 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1315610 | CHD1 | chromodomain helicase DNA binding protein 1 | The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chro mosomal DNA template. [provided by RefSeq, Jul 2008] | 5 | 98853985 | 98929007 | Human | 171 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315611 | Chd1 | chromodomain helicase DNA binding protein 1 | Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and methylated histone binding activity. Acts upstream of or within chromatin remodeling. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleus. Is ex pressed in early conceptus and primary oocyte. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and prostate cancer. Orthologous to human CHD1 (chromodomain helicase DNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2025] | 17 | 15925229 | 15992874 | Mouse | 165 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8707748 | Chd1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits histone H3K4me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); host-mediated activation of viral transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (ortholog); nuclear chromosome (ortholog); nucleus (ortholog) | NW_004955418 | 14200618 | 14268361 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12007034 | CHD1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resista nt prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN chromatin (inferred); cytoplasm (inferred); nuclear chromosome (inferred) | 5 | 94165414 | 94238836 | Bonobo | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12401017 | CHD1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits ATP binding (inferred); DNA binding (inferred); histone H3K4me3 reader activity (inferred); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resistant prostate carcinoma ( ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (inferred); nuclear chromosome (inferred); nucleus (inferred) | 3 | 11288873 | 11359972 | Dog | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12454973 | Chd1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resista nt prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN chromatin (inferred); cytoplasm (inferred); nuclear chromosome (inferred) | NW_004936523 | 4945650 | 5016209 | Squirrel | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14230321 | CHD1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits ATP binding (inferred); DNA binding (inferred); helicase activity (inferred); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Col orectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (inferred); nuclear chromosome (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14371103 | CHD1 | | | | | | Yeast | | symbol | gene, null |
| 14371104 | Chd1 | | | | | | Fly | | symbol | gene, null |
| 18734205 | CHD1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resista nt prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN chromatin (inferred); cytoplasm (inferred); nuclear chromosome (inferred) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914854 | Chd1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits histone H3K4me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); host-mediated activation of viral transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (ortholog); nuclear chromosome (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238536 | chd1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625985717 | Chd1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits histone H3K4me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); host-mediated activation of viral transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (ortholog); nuclear chromosome (ortholog); nucleus (ortholog) | | | | Black Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239355 | chd1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246654 | chd1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 11575312 | CHD1-DT | CHD1 divergent transcript | INTERACTS WITH aristolochic acid A | 5 | 98928562 | 99004021 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1310166 | Chct1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; benzo[a]pyrene | 10 | 70537206 | 70548972 | Rat | 20 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1331976 | Chct1 | CHD1 helical C-terminal domain containing 1 | Predicted to be located in nucleus. Is expressed in testis. Orthologous to human CHCT1 (CHD1 helical C-terminal domain containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 85031023 | 85072042 | Mouse | 27 | old_gene_name , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1603589 | CHCT1 | CHD1 helical C-terminal domain containing 1 | Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 17 | 60421214 | 60431426 | Human | 20 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 8813303 | Chct1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (ortholog) | NW_004955451 | 1709938 | 1719278 | Chinchilla | 1 | name | gene, protein-coding, MODEL [RefSeq] |
| 11762235 | CHCT1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (inferred) | 17 | 54506270 | 54516481 | Bonobo | 2 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12165573 | CHCT1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (inferred) | 9 | 36073469 | 36082236 | Dog | 2 | name | gene, protein-coding, MODEL [RefSeq] |
| 12536827 | Chct1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (inferred) | NW_004936490 | 1990868 | 2001188 | Squirrel | 2 | name | gene, protein-coding, MODEL [RefSeq] |
| 14070300 | CHCT1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (inferred) | | | | Pig | 1 | name | gene, protein-coding, MODEL [RefSeq] |
| 18496662 | CHCT1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (inferred) | | | | Green Monkey | 2 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626015173 | Chct1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (ortholog) | | | | Black Rat | 1 | name | gene, protein-coding, MODEL [RefSeq] |
| 1311935 | Chd1l | chromodomain helicase DNA binding protein 1-like | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); histone reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH CAKUT (ortholog); Dwarfis m (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH 17beta-estradiol; 2,4,6-trinitrotoluene; 6-propyl-2-thiouracil | 2 | 187819869 | 187906359 | Rat | 126 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323647 | CHD1L | chromodomain helicase DNA binding protein 1 like | This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers. [provided by RefSeq, Feb 2017] | 1 | 147172747 | 147295762 | Human | 123 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1323648 | Chd1l | chromodomain helicase DNA binding protein 1-like | Predicted to enable several functions, including ATP hydrolysis activity; nucleosome binding activity; and poly-ADP-D-ribose modification-dependent protein binding activity. Predicted to be involved in DNA repair and chromatin remodeling. Predicted to be located in cytosol; nucleoplasm; and plasma m embrane. Predicted to be active in nucleus and site of double-strand break. Is expressed in genitourinary system and liver. Orthologous to human CHD1L (chromodomain helicase DNA binding protein 1 like). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 97468056 | 97517538 | Mouse | 143 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8780852 | Chd1l | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); histone reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH CAKUT (ortholog); Dwarfis m (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); site of DNA damage (ortholog) | NW_004955568 | 1132594 | 1189176 | Chinchilla | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12025223 | CHD1L | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); DNA repair (inferred); ASSOCIATED WITH CAKUT (ortholog); Dwarfism (ortholog) ; hereditary breast ovarian cancer syndrome (ortholog); FOUND IN site of DNA damage (ortholog) | 1 | 122595246 | 122720788 | Bonobo | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12315229 | CHD1L | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); DNA repair (inferred); ASSOCIATED WITH CAKUT (ortholog); Dwarfism (ortholog) ; hereditary breast ovarian cancer syndrome (ortholog); FOUND IN site of DNA damage (ortholog) | 17 | 57725823 | 57806065 | Dog | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12677746 | Chd1l | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); DNA repair (inferred); ASSOCIATED WITH CAKUT (ortholog); Dwarfism (ortholog) ; hereditary breast ovarian cancer syndrome (ortholog); FOUND IN site of DNA damage (ortholog) | NW_004937024 | 164309 | 216967 | Squirrel | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14074002 | CHD1L | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); DNA repair (inferred); ASSOCIATED WITH CAKUT (ortholog); Dwarfism (ortholog) ; hereditary breast ovarian cancer syndrome (ortholog); FOUND IN site of DNA damage (ortholog) | | | | Pig | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18502229 | CHD1L | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent chromatin remodeler activity (inferred); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); DNA repair (inferred); ASSOCIATED WITH CAKUT (ortholog); Dwarfism (ortholog) ; hereditary breast ovarian cancer syndrome (ortholog); FOUND IN site of DNA damage (ortholog) | | | | Green Monkey | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936592 | Chd1l | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); histone reader activity (ortholog); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); DNA repair (inferred); ASSOCIATED WITH CAKUT (ortholog); Dwarfis m (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nucleoplasm (ortholog); site of DNA damage (ortholog); site of double-strand break (ortholog) | | | | Naked Mole-Rat | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626063887 | Chd1l | chromodomain helicase DNA binding protein 1 like | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); histone reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH CAKUT (ortholog); Dwarfis m (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); site of DNA damage (ortholog) | | | | Black Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11436392 | Chd1l2 | chromodomain helicase DNA binding protein 1 like 2 | | 1 | 65311303 | 65336895 | Rat | | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |