| 619933 | Ccl22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH anti -basement membrane glomerulonephritis; asthma; Pain; FOUND IN extracellular space (ortholog); INTERACTS WITH 2-amino-2-deoxy-D-glucopyranose; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 19 | 10263589 | 10270359 | Rat | 173 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1351526 | CCL22 | C-C motif chemokine ligand 22 | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine enco ded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014] | 16 | 57357909 | 57366189 | Human | 184 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551080 | Ccl22 | C-C motif chemokine ligand 22 | Predicted to enable CCR chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; chemokine-mediated signaling pathway; and eosinophil chemotaxis. Located in extracellu lar space. Is expressed in dermis; epidermis; inguinal lymph node; thymus; and thymus primordium. Orthologous to human CCL22 (C-C motif chemokine ligand 22). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 95472312 | 95478016 | Mouse | 179 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8918654 | Ccl22 | C-C motif chemokine ligand 22 | INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular space (ortholog) | NW_004955433 | 15002001 | 15007324 | Chinchilla | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11897150 | CCL22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cell chemotaxis (inferred); chemokine-mediated signaling pathway (in ferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 16 | 37631861 | 37640208 | Bonobo | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12158958 | CCL22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN cell chemotaxis (inferred); chemotaxis (inferred); immune response (inferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog ); FOUND IN extracellular region (inferred); extracellular space (inferred) | 2 | 59039650 | 59045519 | Dog | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12500291 | Ccl22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cell chemotaxis (inferred); chemokine-mediated signaling pathway (in ferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936475 | 9432505 | 9436240 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13958185 | CCL22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN cell chemotaxis (inferred); chemotaxis (inferred); immune response (inferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog ); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Pig | 44 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18720726 | CCL22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cell chemotaxis (inferred); chemokine-mediated signaling pathway (in ferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Green Monkey | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18908062 | Ccl22 | C-C motif chemokine ligand 22 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cell chemotaxis (inferred); chemokine-mediated signaling pathway (in ferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Naked Mole-Rat | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625847977 | Ccl22 | C-C motif chemokine ligand 22 | INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular space (ortholog) | | | | Black Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |