CCL22 (C-C motif chemokine ligand 22) - Rat Genome Database

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Pathways
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Gene: CCL22 (C-C motif chemokine ligand 22) Sus scrofa
Analyze
Symbol: CCL22
Name: C-C motif chemokine ligand 22
RGD ID: 13958185
Description: ENCODES a protein that exhibits chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN chemotaxis (inferred); eosinophil chemotaxis (inferred); immune response (inferred); ASSOCIATED WITH anti-basement membrane glomerulonephritis (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-C motif chemokine 22; chemokine (C-C motif) ligand 22
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,296,637 - 19,302,737 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,296,726 - 19,301,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,265,026 - 17,294,055 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CCL22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,296,637 - 19,302,737 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,296,726 - 19,301,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,265,026 - 17,294,055 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCL22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,357,909 - 57,366,189 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,358,783 - 57,366,189 (+)EnsemblGRCh38hg38GRCh38
GRCh371657,392,695 - 57,400,101 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,950,219 - 55,957,602 (+)NCBINCBI36Build 36hg18NCBI36
Build 341655,950,218 - 55,957,602NCBI
Celera1641,892,697 - 41,900,098 (+)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1643,260,573 - 43,267,982 (+)NCBIHuRef
CHM1_11658,800,929 - 58,808,348 (+)NCBICHM1_1
T2T-CHM13v2.01663,153,028 - 63,161,306 (+)NCBIT2T-CHM13v2.0
Ccl22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,472,312 - 95,478,016 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,472,218 - 95,478,327 (+)EnsemblGRCm39 Ensembl
GRCm38894,745,684 - 94,751,388 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,745,590 - 94,751,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,269,584 - 97,275,288 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36897,634,719 - 97,640,828 (+)NCBIMGSCv36mm8
Celera899,073,978 - 99,079,588 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.75NCBI
Ccl22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,263,589 - 10,270,359 (-)NCBIGRCr8
mRatBN7.21910,257,602 - 10,264,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,257,601 - 10,264,400 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1910,220,769 - 10,227,547 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,987,615 - 10,994,405 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,274,563 - 10,281,354 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,674,189 - 10,681,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,674,189 - 10,681,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01910,668,403 - 10,675,173 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,697,324 - 10,704,129 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11910,703,571 - 10,708,932 (-)NCBI
Celera1910,143,508 - 10,150,151 (-)NCBICelera
Cytogenetic Map19p13NCBI
Ccl22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,001,930 - 15,008,032 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,002,001 - 15,007,324 (+)NCBIChiLan1.0ChiLan1.0
CCL22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21866,826,127 - 66,834,428 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11672,746,907 - 72,755,202 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01637,631,861 - 37,640,208 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11656,765,370 - 56,770,650 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1656,765,367 - 56,771,213 (+)Ensemblpanpan1.1panPan2
CCL22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,039,650 - 59,045,519 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,040,539 - 59,045,625 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,669,094 - 55,674,886 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0259,577,991 - 59,583,780 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,579,632 - 59,583,743 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1256,409,552 - 56,415,344 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,417,248 - 57,423,037 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,310,530 - 58,316,323 (-)NCBIUU_Cfam_GSD_1.0
Ccl22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,151,805 - 50,156,642 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364759,432,505 - 9,436,240 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364759,432,505 - 9,436,240 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103233057
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,297,206 - 43,305,662 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,297,897 - 43,305,642 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604732,922,605 - 32,927,750 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccl22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,694,735 - 28,700,827 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474628,694,879 - 28,700,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCL22
164 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system reproductive system respiratory system
High
Medium
Low 7 2 3 2
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003121   ⟹   ENSSSCP00000003040
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl619,296,711 - 19,302,000 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000099611   ⟹   ENSSSCP00000075301
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl619,296,637 - 19,302,737 (+)Ensembl
RefSeq Acc Id: NM_001256776   ⟹   NP_001243705
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1619,296,726 - 19,301,506 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001243705 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ACN22081 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000075301
  ENSSSCP00000075301.1
  ENSSSCP00015026541.1
  ENSSSCP00030038448.1
  ENSSSCP00050020560.1
Reference Protein Sequences
RefSeq Acc Id: NP_001243705   ⟸   NM_001256776
- Peptide Label: precursor
- UniProtKB: G8XRI5 (UniProtKB/TrEMBL),   A0A8D0P0U1 (UniProtKB/TrEMBL),   F1RF20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000003040   ⟸   ENSSSCT00000003121
RefSeq Acc Id: ENSSSCP00000075301   ⟸   ENSSSCT00000099611
Protein Domains
Chemokine interleukin-8-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002821 Ensembl
  ENSSSCG00000056251 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015049751 UniProtKB/TrEMBL
  ENSSSCG00030059972 UniProtKB/TrEMBL
  ENSSSCG00050036603 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000099611 ENTREZGENE
  ENSSSCT00000099611.1 UniProtKB/TrEMBL
  ENSSSCT00015066258.1 UniProtKB/TrEMBL
  ENSSSCT00030083702.1 UniProtKB/TrEMBL
  ENSSSCT00050049253.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/TrEMBL
  Chemokine_CC_CS UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/TrEMBL
KEGG Report ssc:100516016 UniProtKB/TrEMBL
NCBI Gene CCL22 ENTREZGENE
PANTHER PTHR12015 UniProtKB/TrEMBL
  PTHR12015:SF102 UniProtKB/TrEMBL
Pfam IL8 UniProtKB/TrEMBL
PROSITE SMALL_CYTOKINES_CC UniProtKB/TrEMBL
SMART SCY UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/TrEMBL
UniProt A0A8D0P0U1 ENTREZGENE, UniProtKB/TrEMBL
  F1RF20 ENTREZGENE, UniProtKB/TrEMBL
  G8XRI5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:86339 ENTREZGENE