| 1307282 | Brd4 | bromodomain containing 4 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to glucose stimulus; chromatin remodeling (ortholog); chromosome segregation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Diabet ic Cardiomyopathies; acute myeloid leukemia (ortholog); alopecia (ortholog); FOUND IN chromatin (ortholog); chromosome (ortholog); condensed nuclear chromosome (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bisphenol A | 7 | 11866997 | 11946575 | Rat | 216 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1316385 | BRD4 | bromodomain containing 4 | The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targ eting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] | 19 | 15235519 | 15332539 | Human | 386 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316386 | Brd4 | bromodomain containing 4 | Enables several functions, including RNA polymerase II C-terminal domain binding activity; lysine-acetylated histone binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of T-helper 17 cell lineage commitment. Acts upstream of or within chromosome segregati on; inner cell mass cell proliferation; and protein autophosphorylation. Located in chromatin and condensed nuclear chromosome. Part of cyclin/CDK positive transcription elongation factor complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; pancreas; and sensory organ. Used to study nephrocalcinosis. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 6; colon cancer; and idiopathic pulmonary fibrosis. Orthologous to human BRD4 (bromodomain containing 4). [provided by Alliance of Genome Resources, Apr 2025] | 17 | 32415246 | 32503717 | Mouse | 251 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8830561 | Brd4 | bromodomain containing 4 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromatin remodeling (ortholog); chromosome segregation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromatin (ortholog); chromosome (ortholog); condensed nuclear chromosome (ortholog) | NW_004955495 | 7959033 | 7989216 | Chinchilla | 111 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11857579 | BRD4 | bromodomain containing 4 | ENCODES a protein that exhibits DNA binding (ortholog); GTP-dependent protein kinase activity (ortholog); histone reader activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modif ication pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromosome (ortholog); cyclin/CDK positive transcription elongation factor complex (ortholog) | 19 | 14768239 | 14805770 | Bonobo | 112 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12361879 | BRD4 | bromodomain containing 4 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED W ITH acute myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromatin (ortholog); chromosome (ortholog); condensed nuclear chromosome (ortholog) | 20 | 46844795 | 46927620 | Dog | 115 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12663195 | Brd4 | bromodomain containing 4 | ENCODES a protein that exhibits DNA binding (ortholog); GTP-dependent protein kinase activity (ortholog); histone reader activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modif ication pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromosome (ortholog); cyclin/CDK positive transcription elongation factor complex (ortholog) | NW_004936596 | 5176682 | 5246102 | Squirrel | 111 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14249668 | BRD4 | bromodomain containing 4 | ENCODES a protein that exhibits DNA binding (ortholog); GTP-dependent protein kinase activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acu te myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromatin (ortholog); chromosome (ortholog); cyclin/CDK positive transcription elongation factor complex (ortholog) | | | | Pig | 113 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18741037 | BRD4 | bromodomain containing 4 | ENCODES a protein that exhibits DNA binding (ortholog); GTP-dependent protein kinase activity (ortholog); histone reader activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modif ication pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromosome (ortholog); cyclin/CDK positive transcription elongation factor complex (ortholog) | | | | Green Monkey | 112 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902091 | Brd4 | bromodomain containing 4 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED W ITH acute myeloid leukemia (ortholog); alopecia (ortholog); autosomal dominant polycystic kidney disease (ortholog); FOUND IN chromosome (ortholog); condensed nuclear chromosome (ortholog); cyclin/CDK positive transcription elongation factor complex (ortholog) | | | | Naked Mole-Rat | 114 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256510 | brd4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155252277 | brd4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257686 | brd4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1306385 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (ortholog); SWI/SNF complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 1 | 85790093 | 85867656 | Rat | 61 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1314970 | BICRA | BRD4 interacting chromatin remodeling complex associated protein | Enables transcription regulator activator activity. Involved in positive regulation of DNA-templated transcription. Located in nucleus. Part of SWI/SNF complex. Implicated in Coffin-Siris syndrome 12. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 47608196 | 47703277 | Human | 160 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 1618114 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | Predicted to enable transcription regulator activator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 12. Orthologous to human BICRA (BRD4 RD4 interacting chromatin remodeling complex associated protein). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 15704596 | 15785047 | Mouse | 99 | name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8728506 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (ortholog); SWI/SNF complex (ortholog) | NW_004955574 | 1463656 | 1484709 | Chinchilla | 14 | name | gene, protein-coding, MODEL [RefSeq] |
| 11677791 | BICRA | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (inferred); SWI/SNF complex (inferred) | 19 | 44600696 | 44697643 | Bonobo | 15 | name | gene, protein-coding, MODEL [RefSeq] |
| 12298111 | BICRA | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (inferred); SWI/SNF complex (inferred) | 1 | 108344245 | 108427133 | Dog | 15 | name | gene, protein-coding, MODEL [RefSeq] |
| 12645490 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (inferred); SWI/SNF complex (inferred) | NW_004936664 | 1241048 | 1310114 | Squirrel | 15 | name | gene, protein-coding, MODEL [RefSeq] |
| 13865017 | BICRA | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (inferred); SWI/SNF complex (inferred) | | | | Pig | 15 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18785802 | BICRA | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (inferred); SWI/SNF complex (inferred) | | | | Green Monkey | 15 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18920541 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (ortholog) | | | | Naked Mole-Rat | 13 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626003848 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (ortholog); SWI/SNF complex (ortholog) | | | | Black Rat | 14 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 32730955 | LOC117979566 | BRD4-interacting chromatin-remodeling complex-associated protein | | 3 | 195040921 | 195045573 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 1313852 | Bicral | BRD4 interacting chromatin remodeling complex associated protein like | Predicted to be involved in positive regulation of DNA-templated transcription. Part of SWI/SNF complex. Is expressed in several structures, including genitourinary system; heart; nervous system; respiratory system; and sensory organ. Orthologous to human BICRAL (BICRA like chromatin remodeling comp lex associated protein). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 47109046 | 47201329 | Mouse | 92 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1305680 | Bicral | BICRA like chromatin remodeling complex associated protein | ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 9 | 21597886 | 21682985 | Rat | 68 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1313851 | BICRAL | BICRA like chromatin remodeling complex associated protein | Predicted to be involved in positive regulation of DNA-templated transcription. Part of SWI/SNF complex. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 42746339 | 42868556 | Human | 77 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 9068228 | Bicral | BICRA like chromatin remodeling complex associated protein | ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (ortholog) | NW_004955437 | 8841830 | 8896391 | Chinchilla | 6 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11897525 | BICRAL | BICRA like chromatin remodeling complex associated protein | INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (inferred) | 6 | 42338441 | 42457989 | Bonobo | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12082780 | BICRAL | BICRA like chromatin remodeling complex associated protein | ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (inferred) | 12 | 11358790 | 11436002 | Dog | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12516360 | Bicral | BICRA like chromatin remodeling complex associated protein | INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (inferred) | NW_004936476 | 17037595 | 17111786 | Squirrel | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14059599 | BICRAL | BICRA like chromatin remodeling complex associated protein | ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (inferred) | | | | Pig | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18622202 | BICRAL | BICRA like chromatin remodeling complex associated protein | INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (inferred) | | | | Green Monkey | 7 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18917711 | Bicral | BICRA like chromatin remodeling complex associated protein | INVOLVED IN positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (inferred) | | | | Naked Mole-Rat | 6 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626101114 | Bicral | BICRA like chromatin remodeling complex associated protein | ASSOCIATED WITH autism spectrum disorder (ortholog); prostate cancer (ortholog); FOUND IN SWI/SNF complex (ortholog) | | | | Black Rat | 5 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |