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18 records found for search term Alpi
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2099Alpialkaline phosphatase, intestinalENCODES a protein that exhibits alkaline phosphatase activity; magnesium ion binding; protein homodimerization activity; INVOLVED IN dephosphorylation; cellular response to BMP stimulus (ortholog); PARTICIPATES IN folate metabolic pathway; ASSOCIATED WITH Dysbiosis; Crohn's disease (ortholog); infla99522131495224780Rat92symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
737157ALPIalkaline phosphatase, intestinalThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and i2232456153232460753Human94symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1623897Alpialkaline phosphatase, intestinalPredicted to enable several functions, including alkaline phosphatase activity; metal ion binding activity; and protein homodimerization activity. Acts upstream of or within cellular response to BMP stimulus. Predicted to be located in external side of plasma membrane. Predicted to be active in extr18702572487029328Mouse97symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
11983521ALPIalkaline phosphatase, intestinalENCODES a protein that exhibits alkaline phosphatase activity (ortholog); magnesium ion binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to BMP stimulus (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); Dysbiosis (ort2B119687673119692300Bonobo25symbolgene, protein-coding, MODEL [RefSeq]
12192371ALPIalkaline phosphatase, intestinalENCODES a protein that exhibits alkaline phosphatase activity (ortholog); magnesium ion binding (ortholog); protease binding (ortholog); INVOLVED IN cellular response to BMP stimulus (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); Dysbiosis (ortholog); inflammat254410741844110947Dog29symbolgene, protein-coding, MODEL [RefSeq]
18916253Alpialkaline phosphatase, intestinalENCODES a protein that exhibits alkaline phosphatase activity (ortholog); magnesium ion binding (ortholog); protease binding (ortholog); INVOLVED IN cellular response to BMP stimulus (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); Dysbiosis (ortholog); inflammatNaked Mole-Rat25symbolgene, protein-coding, MODEL [RefSeq]
598130607ALPIalkaline phosphatase, intestinalENCODES a protein that exhibits alkaline phosphatase activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); ASSOCIATED WITH Crohn's disease (ortholog); inflammatory bowel disease (ortholog); ulcerative colitis (ortholog); FOUND IN plasma membrane (inferred); side of membraGreen Monkey14symbolgene, protein-coding, MODEL [RefSeq]
155236300alpi.1Tropical Clawed Frogsymbolgene, null
288083127alpi.2Tropical Clawed Frogsymbolgene, null
155236299alpi.1.LAfrican Clawed Frogsymbolgene, null
284690924alpi.2.LAfrican Clawed Frogsymbolgene, null
1314395ALPPalkaline phosphatase, placentalThe protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one mag2232378751232382889Human103old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
12609386LOC101973915intestinal-type alkaline phosphataseENCODES a protein that exhibits alkaline phosphatase activity (ortholog); magnesium ion binding (ortholog); protease binding (ortholog); INVOLVED IN cellular response to BMP stimulus (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); Dysbiosis (ortholog); inflammatNW_00493652546162124619932Squirrel25old_gene_symbolgene, protein-coding, MODEL [RefSeq]
8949434LOC102017190intestinal-type alkaline phosphataseNW_00495545335032263506869Chinchillaold_gene_symbolgene, protein-coding, MODEL [RefSeq]
18611167LOC103218081alkaline phosphatase, germ cell typeENCODES a protein that exhibits alkaline phosphatase activity (ortholog); magnesium ion binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to BMP stimulus (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH Dysbiosis (ortholog); FOUND IN external siGreen Monkey12old_gene_symbolgene, protein-coding, MODEL [RefSeq]
621650Akp3alkaline phosphatase 3, intestine, not Mn requiringENCODES a protein that exhibits alkaline phosphatase activity; magnesium ion binding; zinc ion binding; INVOLVED IN response to nutrient levels; PARTICIPATES IN folate metabolic pathway; ASSOCIATED WITH cystic fibrosis (ortholog); Endotoxemia (ortholog); Metabolic Syndrome (ortholog); FOUND IN exter99525258195256616Rat25old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
10148Akp3alkaline phosphatase 3, intestine, not Mn requiringPredicted to enable alkaline phosphatase activity; metal ion binding activity; and protease binding activity. Acts upstream of or within neural tube development; neurogenesis; and post-anal tail morphogenesis. Located in brush border. Is expressed in duodenum; intestine; and jejunum. Human ortholog(18705267687056450Mouse40descriptiongene, protein-coding, VALIDATED [RefSeq]
1314396Alppl2alkaline phosphatase, placental-like 2Enables alkaline phosphatase activity. Located in myofibril. Is expressed in early conceptus; intestine; and testis. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to human ALPG (alkaline phosphatase, germ cell); ALPI (alkal18701441287023656Mouse71descriptiongene, protein-coding, VALIDATED [RefSeq]