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Gene: ALPI (alkaline phosphatase, intestinal) Homo sapiens
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Symbol: ALPI
Name: alkaline phosphatase, intestinal
Description: Exhibits protease binding activity. Predicted to be involved in cellular response to BMP stimulus and dephosphorylation. Localizes to plasma membrane. Implicated in inflammatory bowel disease. Biomarker of Crohn's disease and ulcerative colitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alkaline phosphatase 1, intestinal, defined by ssr; alkaline phosphomonoesterase; glycerophosphatase; IAP; intestinal alkaline phosphatase; intestinal-type alkaline phosphatase; Kasahara isozyme
Orthologs:
Mus musculus (house mouse) : Alpi (alkaline phosphatase, intestinal)  MGI  Alliance
Rattus norvegicus (Norway rat) : Alpi (alkaline phosphatase, intestinal)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ALPI (alkaline phosphatase, intestinal)
Canis lupus familiaris (dog) : ALPI (alkaline phosphatase, intestinal)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alpi (alkaline phosphatase, intestinal)
Chlorocebus sabaeus (African green monkey) : ALPI (alkaline phosphatase, intestinal)
Heterocephalus glaber (naked mole-rat) : Alpi (alkaline phosphatase, intestinal)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2232,456,125 - 232,460,753 (+)EnsemblGRCh38hg38GRCh38
GRCh382232,456,153 - 232,460,753 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372233,320,833 - 233,325,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,029,077 - 233,032,986 (+)NCBINCBI36hg18NCBI36
Build 342233,146,369 - 233,150,245NCBI
Celera2227,085,143 - 227,089,052 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2225,171,620 - 225,175,529 (+)NCBIHuRef
CHM1_12233,326,941 - 233,331,574 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on ALPI
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737157
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.