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Gene: Alppl2 (alkaline phosphatase, placental-like 2) Mus musculus
Symbol: Alppl2
Name: alkaline phosphatase, placental-like 2
RGD ID: 1314396
Description: Exhibits alkaline phosphatase activity. Predicted to be involved in dephosphorylation. Localizes to myofibril. Is expressed in early conceptus; intestine; and testis. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to human ALPG (alkaline phosphatase, germ cell); ALPI (alkaline phosphatase, intestinal); and ALPP (alkaline phosphatase, placental); PARTICIPATES IN folate metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ak; Akp5; alkaline phosphatase 5; alkaline phosphatase, germ cell type; alkaline phosphatase, placental-like; Alpg; C77216; D1Ertd816; D1Ertd816e; EAP; embryonic alkaline phosphatase; embryonic-type alkaline phosphatase
Related Pseudogenes: Akp-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39187,014,412 - 87,023,656 (-)NCBI
GRCm38187,086,690 - 87,095,934 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,086,694 - 87,089,928 (-)EnsemblGRCm38mm10GRCm38
MGSCv37188,983,265 - 88,986,503 (-)NCBIGRCm37mm9NCBIm37
MGSCv36188,917,861 - 88,921,082 (-)NCBImm8
Celera190,058,871 - 90,062,109 (-)NCBICelera
Cytogenetic Map1C5NCBI
cM Map144.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Alppl2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314396
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.