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40 records found for search term Aim2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1307283Aim2absent in melanoma 2ENCODES a protein that exhibits cysteine-type endopeptidase activator activity (ortholog); double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); AIM2 inflammasome complex assemb138839751688439325Rat164symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1316387AIM2absent in melanoma 2AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]1159055051159147132Human155symbol , old_gene_name , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1622795Aim2absent in melanoma 2Enables several functions, including identical protein binding activity; pattern recognition receptor activity; and signaling adaptor activity. Involved in several processes, including AIM2 inflammasome complex assembly; negative regulation of phosphatidylinosit1173177105173293606Mouse210symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
12037888AIM2absent in melanoma 2ENCODES a protein that exhibits cysteine-type endopeptidase activator activity (inferred); DNA binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); cellular response to xenobiotic stimulus (ortholog); positive regulation of interleu1134413232134540344Bonobo64symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12482671Aim2absent in melanoma 2ENCODES a protein that exhibits cysteine-type endopeptidase activator activity (inferred); DNA binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); cellular response to xenobiotic stimulus (ortholog); positive regulation of interleuNW_00493674014478691460836Squirrel64symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14371376AIM2Yeastsymbolgene, null
18768746AIM2absent in melanoma 2ENCODES a protein that exhibits cysteine-type endopeptidase activator activity (inferred); DNA binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); cellular response to xenobiotic stimulus (ortholog); positive regulation of interleuGreen Monkey64symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
626141533Aim2absent in melanoma 2ENCODES a protein that exhibits cysteine-type endopeptidase activator activity (ortholog); double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); AIM2 inflammasome complex assembBlack Rat50symbol , old_gene_name , descriptiongene, protein-coding, MODEL [RefSeq]
8896148LOC102030177interferon-inducible protein AIM2NW_0049554681083614110910712Chinchillaname , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
13320994LOC111094466uncharacterized LOC111094466382285850822883477Dogold_gene_namegene, protein-coding, MODEL [RefSeq]
11965923PYDC5pyrin domain containing 5INVOLVED IN cellular response to cytokine stimulus (inferred); cellular response to interferon-beta (inferred); cellular response to virus (inferred)1134354730134355243Bonobo8old_gene_namegene, protein-coding, MODEL [RefSeq]
14375241AIM22Yeastsymbolgene, null
14375244AIM25Yeastsymbolgene, null
14375256AIM29Yeastsymbolgene, null
1606162C2orf76chromosome 2 open reading frame 76INTERACTS WITH 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one; 2-hydroxypropanoic acid2119281130119367151Human28old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
626128072Casp1caspase 1ENCODES a protein that exhibits CARD domain binding (ortholog); cysteine-type endopeptidase activity (ortholog); cytokine binding (ortholog); INVOLVED IN AIM2 inflammasome complex assembly (ortholog); cellular response to lipopolysaccharide (ortholog); cellular Black Rat160descriptiongene, protein-coding, MODEL [RefSeq]
12530123LOC101954543caspase-1-likeENCODES a protein that exhibits caspase binding (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN AIM2 inflammasome complex assembly (inferred); defense response to bacterium (inferred); defenseNW_00493655132300603240496Squirrel32descriptiongene, protein-coding, MODEL [RefSeq]
32726499CARD16caspase recruitment domain family member 16ENCODES a protein that exhibits CARD domain binding (inferred); caspase binding (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN cellular response to lipopolysaccharide (inferred); negative regulation of interleukin-1 beta production (inferred); negative regulation of lipopol119998185499985839Bonobo25descriptiongene, protein-coding, MODEL [RefSeq]
20865634CARD18caspase recruitment domain family member 18ENCODES a protein that exhibits CARD domain binding (inferred); caspase binding (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN negative regulation of interleukin-1 beta production (inferred); proteolysis (inferred); regulation of apoptotic process (inferred); FOUND IN AIM2Green Monkey14descriptiongene, protein-coding
2274Casp1caspase 1ENCODES a protein that exhibits scaffold protein binding; CARD domain binding (ortholog); cysteine-type endopeptidase activity (ortholog); INVOLVED IN lung development; memory; microglial cell activation; PARTICIPATES IN interleukin-1 signaling pathway; type II interferon signaling pathway; amyotrop81074633810882295Rat1057descriptiongene, protein-coding, VALIDATED [RefSeq]
731729Casp1caspase 1Enables cysteine-type endopeptidase activity. Involved in several processes, including AIM2 inflammasome complex assembly; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of interleukin-1 beta production. Acts upstream of 952985175307281Mouse1168descriptiongene, protein-coding, VALIDATED [RefSeq]
14133292CASP1caspase 1, apoptosis-related cysteine peptidaseENCODES a protein that exhibits CARD domain binding (ortholog); cysteine-type endopeptidase activity (ortholog); cytokine binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); cellular response to mechanical stimulus (ortholog); cellular response to type II interferon (Pig190descriptiongene, protein-coding, PROVISIONAL [RefSeq]
12113986CASP4caspase 4, apoptosis-related cysteine peptidaseENCODES a protein that exhibits CARD domain binding (ortholog); cysteine-type endopeptidase activity (ortholog); lipid binding (ortholog); INVOLVED IN cellular response to amyloid-beta (ortholog); defense response to bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); ASSOC52713377827147954Dog85descriptiongene, protein-coding, PROVISIONAL [RefSeq]
20865897CASP5caspase 5ENCODES a protein that exhibits caspase binding (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN apoptotic process (inferred); cellular response to mechanical stimulus (inferred); protein maturation (inferred); FOUND IN AIM2Green Monkey19descriptiongene, protein-coding
18930377Caspase-12caspase-12ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase activity (inferred); INVOLVED IN intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (inferred); programmed cell death (inferred);Naked Mole-Rat18descriptiongene, protein-coding, MODEL [RefSeq]
2295907Gm12250predicted gene 12250Enables G protein activity and membrane destabilizing activity. Involved in several processes, including defense response to other organism; disruption of plasma membrane integrity in another organism; and positive regulation of defense response. Acts upstream of or within AIM2115807466958081024Mouse29descriptiongene, protein-coding, PROVISIONAL [RefSeq]
11928364LOC100985633caspase-1ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); negative regulation of interleukin-1 beta production (ortholog); FOUND IN AIM2 inflammasome complex (inferred); IPAF inflammasom11100031979100041771Bonobo16descriptiongene, protein-coding, MODEL [RefSeq]
11955748LOC100991705inactive caspase-12ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN proteolysis (inferred); regulation of apoptotic process (inferred); regulation of inflammatory response (inferred); FOUND IN AIM2119982642299839349Bonobo8descriptiongene, protein-coding, MODEL [RefSeq]
18935858LOC101725179caspase-1ENCODES a protein that exhibits caspase binding (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN apoptotic process (inferred); inflammatory response (inferred); positive regulation of interleukin-1 beta production (inferred); FOUNDNaked Mole-Rat24descriptiongene, protein-coding, MODEL [RefSeq]
12566707LOC101964473caspase-4-likeENCODES a protein that exhibits caspase binding (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN defense response to bacterium (inferred); defense response to Gram-positive bacterium (inferred); detection of lipopolysaccharide (infNW_00493655132423813269821Squirrel31descriptiongene, protein-coding, MODEL [RefSeq]
18426456LOC103248363caspase-1-likeENCODES a protein that exhibits caspase binding (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN apoptotic process (inferred); inflammatory response (inferred); positive regulation of interleukin-1 beta production (inferred); FOUNDGreen Monkey23descriptiongene, protein-coding, MODEL [RefSeq]
18373878LOC103248365caspase-1ENCODES a protein that exhibits CARD domain binding (ortholog); cytokine binding (ortholog); endopeptidase activity (ortholog); INVOLVED IN AIM2 inflammasome complex assembly (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to meGreen Monkey166descriptiongene, protein-coding, MODEL [RefSeq]
18397972LOC103248368caspase-12ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN apoptotic process (inferred); intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (inferred); proteinGreen Monkey19descriptiongene, protein-coding, MODEL [RefSeq]
18930433PycardPYD and CARD domain containingENCODES a protein that exhibits BMP receptor binding (ortholog); enzyme binding (ortholog); interleukin-6 receptor binding (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to interleukin-1 (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPATES INaked Mole-Rat145descriptiongene, protein-coding, MODEL [RefSeq]
13461834PYDC5pyrin domain containing 5Involved in cellular response to interferon-beta; cellular response to virus; and negative regulation of AIM2 inflammasome complex assembly. [provided by Alliance of Genome Resources, Jul 2025]1158999971159002751Human8descriptiongene, protein-coding, VALIDATED [RefSeq]
40899742PYDC5pyrin domain containing 5INVOLVED IN cellular response to interferon-beta (ortholog); cellular response to virus (ortholog); negative regulation of AIM2 inflammasome complex assembly (ortholog)Green Monkey5descriptiongene, protein-coding, MODEL [RefSeq]
1305448Trim11tripartite motif-containing 11ENCODES a protein that exhibits protein domain specific binding (ortholog); protein-macromolecule adaptor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN host-mediated suppression of symbiont invasion (ortholog); innate immune response (ortholog); negative regulation o104425501944270711Rat144descriptiongene, protein-coding, VALIDATED [RefSeq]
8721822Trim11tripartite motif containing 11ENCODES a protein that exhibits protein domain specific binding (ortholog); protein-macromolecule adaptor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN host-mediated suppression of symbiont invasion (ortholog); innate immune response (ortholog); negative regulation oNW_004955581114750123410Chinchilla28descriptiongene, protein-coding, MODEL [RefSeq]
12140797TRIM11tripartite motif containing 11ENCODES a protein that exhibits protein domain specific binding (ortholog); protein-macromolecule adaptor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN host-mediated suppression of symbiont invasion (ortholog); innate immune response (ortholog); negative regulation o14640375647427Dog28descriptiongene, protein-coding, MODEL [RefSeq]
18901692Trim11tripartite motif containing 11ENCODES a protein that exhibits protein domain specific binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of AIM2 inflammasome complex assembly (ortholog); negative regulatioNaked Mole-Rat27descriptiongene, protein-coding, MODEL [RefSeq]