| 1307025 | Actr1a | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN spermatogenesis; microtubule-based process (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN centriole; COPI-coated vesicle; manchette; INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene; bisphenol A | 1 | 255179241 | 255199009 | Rat | 89 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1315973 | ACTR1A | actin related protein 1A | This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripe tal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008] | 10 | 102479229 | 102502712 | Human | 93 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315974 | Actr1a | ARP1 actin-related protein 1A, centractin alpha | Predicted to enable ATP binding activity. Located in myelin sheath. Is expressed in cerebral cortex; ganglia; and trigeminal nerve. Orthologous to human ACTR1A (actin related protein 1A). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 46365252 | 46384180 | Mouse | 96 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8865045 | Actr1a | actin related protein 1A | INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN cell cortex (ortholog); centriole (ortholog); centrosome (ortholog) | NW_004955485 | 7926744 | 7944648 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11811865 | ACTR1A | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN centriole ( ortholog); COPI-coated vesicle (ortholog); dynactin complex (ortholog) | 10 | 99082765 | 99106305 | Bonobo | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12273981 | ACTR1A | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN centriole ( ortholog); COPI-coated vesicle (ortholog); cytoplasm (ortholog) | 28 | 14972512 | 14990434 | Dog | 25 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12457876 | Actr1a | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN centriole ( ortholog); COPI-coated vesicle (ortholog); dynactin complex (ortholog) | NW_004936600 | 3384466 | 3402312 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13887793 | ACTR1A | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN microtubule-based process; spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN centriole (ortholog); COPI-coated vesicle (ortholog); manchette (ortholog) | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18424755 | ACTR1A | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN centriole ( ortholog); COPI-coated vesicle (ortholog); dynactin complex (ortholog) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914476 | Actr1a | actin related protein 1A | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN cell cortex (ortholog); centriole (ortholog); centrosome (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626029396 | Actr1a | actin related protein 1A | INVOLVED IN microtubule-based process (ortholog); spermatogenesis (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH colon cancer (ortholog); Down syndrome (ortholog); FOUND IN cell cortex (ortholog); centriole (ortholog); centrosome (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232490 | actr1a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155232489 | actr1a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245527 | actr1a.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 41010079 | Actr1a-ps1 | actin related protein 1A, pseudogene 1 | | 14 | 98476997 | 98481976 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 15042252 | ACTR1AP1 | ACTR1A pseudogene 1 | | 2 | 110184000 | 110185376 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16566777 | AL121928.1 | novel transcript, antisense to ACTR1A | | | | | Human | | name | gene, lncrna |
| 1316546 | ACTR1B | actin related protein 1B | This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008] | 2 | 97655939 | 97664044 | Human | 80 | description | gene, protein-coding, REVIEWED [RefSeq] |