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52 records found for search term Acot1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
70894Acot1acyl-CoA thioesterase 1ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity; INVOLVED IN long-chain fatty acid metabolic process; negative regulation of cardiac muscle cell apoptotic process; acyl-CoA metabolic process (ortholog); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; ASSOCIATED WITH Hy6109367274109375268Rat280symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1605748ACOT1acyl-CoA thioesterase 1Enables fatty acyl-CoA hydrolase activity. Involved in acyl-CoA metabolic process; long-chain fatty acid metabolic process; and very long-chain fatty acid metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]147349093373543796Human281symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1617592Acot1acyl-CoA thioesterase 1Enables fatty acyl-CoA hydrolase activity. Acts upstream of or within long-chain fatty acid metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human <128405627684064444Mouse282symbol , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
41789708ACOT2acyl-CoA thioesterase 2Bonoboold_gene_symbolgene, protein-coding
12737772LOC101972642acyl-coenzyme A thioesterase 1ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); thiolester hydrolase activity (inferred); INVOLVED IN acyl-CoA metabolic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred)NW_00493648828721632879572Squirrel7old_gene_symbolgene, protein-coding, MODEL [RefSeq]
1615138Acot10acyl-CoA thioesterase 10Enables fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process. Located in mitochondrion. Orthologous to human ACOT9 (acyl-CoA thioesterase 9). [provided by Alliance of Genome Resources, Jul 2025]152066530020666836Mouse31symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1317612ACOT11acyl-CoA thioesterase 11This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures15454822854639192Human100symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1615550Acot11acyl-CoA thioesterase 11Predicted to enable long-chain fatty acyl-CoA hydrolase activity. Involved in negative regulation of cold-induced thermogenesis and response to cold. Predicted to be located in mitochondrial matrix. Predicted to be active in cytosol. Orthologous to human ACOT11 4106601752106662204Mouse123symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
2324815Acot11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); long-chain fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); response to cold (ortholog); response to temperature stimulus (ortholog); FOUND IN cytoplas5126756255126804526Rat97symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8857278Acot11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); long-chain fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); response to cold (ortholog); response to temperature stimulus (ortholog); FOUND IN cytoplasNW_00495546447415044782383Chinchilla9symbolgene, protein-coding, MODEL [RefSeq]
11747259ACOT11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN acyl-CoA metabolic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial matrix (inferred)15382305953884249Bonobo19symbolgene, protein-coding, MODEL [RefSeq]
12120615ACOT11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN fatty acid metabolic process (inferred); lipid metabolic process (inferred); negative regulation of cold-induced thermogenesis (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial matrix55451086554558740Dog19symbolgene, protein-coding, MODEL [RefSeq]
12733553Acot11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN acyl-CoA metabolic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial matrix (inferred)NW_00493652266356756681978Squirrel19symbolgene, protein-coding, MODEL [RefSeq]
14206754ACOT11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN fatty acid metabolic process (inferred); lipid metabolic process (inferred); negative regulation of cold-induced thermogenesis (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial matrixPig19symbolgene, protein-coding, MODEL [RefSeq]
18788720ACOT11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN acyl-CoA metabolic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial matrix (inferred)Green Monkey19symbolgene, protein-coding, MODEL [RefSeq]
18928627Acot11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); response to cold (ortholog); response to temperature stimulus (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial matrix (iNaked Mole-Rat18symbolgene, protein-coding, MODEL [RefSeq]
155255532acot11Tropical Clawed Frogsymbolgene, null
625871109Acot11acyl-CoA thioesterase 11ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); long-chain fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); response to cold (ortholog); response to temperature stimulus (ortholog); FOUND IN cytoplasBlack Rat9symbolgene, protein-coding, MODEL [RefSeq]
619752Acot12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity; identical protein binding; ATP binding (ortholog); INVOLVED IN acyl-CoA metabolic process; acetyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase defic22472164824763686Rat141symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
736721ACOT12acyl-CoA thioesterase 12Enables identical protein binding activity. Predicted to be involved in acetyl-CoA metabolic process. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]58130860981394134Human135symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1557713Acot12acyl-CoA thioesterase 12Enables ATP binding activity and acetyl-CoA hydrolase activity. Acts upstream of or within acetyl-CoA metabolic process. Predicted to be located in intercellular bridge and nucleoplasm. Predicted to be active in cytosol. Is expressed in alimentary system and liver. Orthologous to human ACOT1139188963591934271Mouse172symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8806604Acot12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); acyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathNW_0049554182882931628872629Chinchilla19symbolgene, protein-coding, MODEL [RefSeq]
12044811ACOT12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency pathway; ASSOCIATED WITH53388530233950075Bonobo31symbolgene, protein-coding, MODEL [RefSeq]
12213094ACOT12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); acyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxyl32592835625979688Dog32symbolgene, protein-coding, MODEL [RefSeq]
12452765Acot12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency pathway; ASSOCIATED WITHNW_004936469635663681373Squirrel33symbolgene, protein-coding, MODEL [RefSeq]
14242667ACOT12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); acyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylPig31symbolgene, protein-coding, MODEL [RefSeq]
18563777ACOT12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency pathway; ASSOCIATED WITHGreen Monkey29symbolgene, protein-coding, MODEL [RefSeq]
18915762Acot12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency Naked Mole-Rat27symbolgene, protein-coding, MODEL [RefSeq]
155248129acot12Tropical Clawed Frogsymbolgene, null
625889742Acot12acyl-CoA thioesterase 12ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); acyl-CoA metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathBlack Rat19symbolgene, protein-coding, MODEL [RefSeq]
1306513Acot13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); protein homotetramerization (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta174066840440680876Rat124symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1315172ACOT13acyl-CoA thioesterase 13This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and lo62466707724705046Human131symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1315173Acot13acyl-CoA thioesterase 13Enables fatty acyl-CoA hydrolase activity. Involved in negative regulation of cold-induced thermogenesis. Located in mitochondrial matrix. Is expressed in chondrocranium; hindgut; and midgut. Orthologous to human ACOT13 (acyl-CoA thioesterase 13). [provided by A132500193825015472Mouse162symbol , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
8959910Acot13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); protein homotetramerization (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)NW_00495548323607582375071Chinchilla9symbolgene, protein-coding, MODEL [RefSeq]
11842961ACOT13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN lipid metabolic process (inferred); negative regulation of cold-induced thermogenesis (inferred); protein homotetramerization (inferred); FOUND IN cytoplasm (inferred); cytosol (i62450510424542577Bonobo17symbolgene, protein-coding, MODEL [RefSeq]
12231343ACOT13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN lipid metabolic process (inferred); negative regulation of cold-induced thermogenesis (inferred); protein homotetramerization (inferred); FOUND IN cytoplasm (inferred); cytosol (i352270721422723345Dog17symbolgene, protein-coding, MODEL [RefSeq]
12711194Acot13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); protein homotetramerization (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)NW_004936671952652959723Squirrel9symbolgene, protein-coding, MODEL [RefSeq]
13991270ACOT13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN lipid metabolic process (inferred); negative regulation of cold-induced thermogenesis (inferred); protein homotetramerization (inferred); FOUND IN cytoplasm (inferred); cytosol (iPig18symbolgene, protein-coding, VALIDATED [RefSeq]
18619409ACOT13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN lipid metabolic process (inferred); negative regulation of cold-induced thermogenesis (inferred); protein homotetramerization (inferred); FOUND IN cytoplasm (inferred); cytosol (iGreen Monkey17symbolgene, protein-coding, MODEL [RefSeq]
18911140Acot13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); protein homotetramerization (ortholog); FOUND IN mitochondrial matrix (ortholog)Naked Mole-Rat15symbolgene, protein-coding, MODEL [RefSeq]
155236387acot13Tropical Clawed Frogsymbolgene, null
625999809Acot13acyl-CoA thioesterase 13ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); protein homotetramerization (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)Black Rat9symbolgene, protein-coding, MODEL [RefSeq]
626174865acot11.LAfrican Clawed Frogsymbolgene, null
626178279acot11.LAfrican Clawed Frogsymbolgene, null
626183427acot11.LAfrican Clawed Frogsymbolgene, null
155254915acot12.LAfrican Clawed Frogsymbolgene, null
155256699acot13.SAfrican Clawed Frogsymbolgene, null
1601923THEM5thioesterase superfamily member 5Enables long-chain fatty acyl-CoA hydrolase activity. Involved in long-chain fatty-acyl-CoA metabolic process. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Jul 2025]1151847101151853712Human70old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1558054Acot3acyl-CoA thioesterase 3Enables fatty acyl-CoA hydrolase activity. Involved in acyl-CoA metabolic process and carboxylic acid metabolic process. Located in cytosol and peroxisome. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and respiratory system. Ortho128409891884107174Mouse122descriptiongene, protein-coding, VALIDATED [RefSeq]
1558227Acot5acyl-CoA thioesterase 5Enables fatty acyl-CoA hydrolase activity. Involved in acyl-CoA metabolic process and carboxylic acid metabolic process. Located in cytosol and peroxisome. Orthologous to human ACOT1 (acyl-CoA thioesterase 1) and ACOT2 (acyl-CoA thioesterase 2). [provided by All128411590884122798Mouse47descriptiongene, protein-coding, VALIDATED [RefSeq]
16566354AL031775.1novel transcript, antisense to ACOT13Humannamegene, lncrna
16565426AC005229.2ACOT13 acyl-CoA thioesterase 13, pseudogeneHumannamegene, processed_pseudogene