ACOT13 (acyl-CoA thioesterase 13) - Rat Genome Database

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Gene: ACOT13 (acyl-CoA thioesterase 13) Homo sapiens
Analyze
Symbol: ACOT13
Name: acyl-CoA thioesterase 13
RGD ID: 1315172
HGNC Page HGNC:20999
Description: Enables fatty acyl-CoA hydrolase activity. Involved in protein homotetramerization. Located in mitochondrion and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: acyl-coenzyme A thioesterase 13; hotdog-fold thioesterase superfamily member 2; HT012; hypothalamus protein HT012; MGC4961; palmitoyl-CoA hydrolase; PNAS-27; THEM2; thioesterase superfamily member 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC100301516  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,667,077 - 24,705,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,667,035 - 24,705,065 (+)EnsemblGRCh38hg38GRCh38
GRCh37624,667,305 - 24,705,274 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,775,254 - 24,809,921 (+)NCBINCBI36Build 36hg18NCBI36
Build 34624,775,253 - 24,809,919NCBI
Celera625,900,605 - 25,938,673 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef624,616,687 - 24,654,727 (+)NCBIHuRef
CHM1_1624,671,407 - 24,709,441 (+)NCBICHM1_1
T2T-CHM13v2.0624,537,472 - 24,576,170 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methylcholine  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (EXP)
acetamide  (ISO)
aflatoxin B1  (EXP)
aristolochic acid A  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
chloropicrin  (EXP)
cisplatin  (EXP)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
Dibutyl phosphate  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
folic acid  (ISO)
hydrogen peroxide  (EXP)
isotretinoin  (EXP)
ivermectin  (EXP)
menadione  (EXP)
methidathion  (ISO)
methylmercury chloride  (EXP)
nefazodone  (ISO)
nickel sulfate  (EXP)
nicotine  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
quercetin  (EXP)
resveratrol  (ISO)
rotenone  (EXP,ISO)
Salinomycin  (EXP)
senecionine  (ISO)
sunitinib  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
tunicamycin  (EXP)
urethane  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP)
vincaleukoblastine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytoskeleton  (IEA)
cytosol  (IEA,TAS)
mitochondrial matrix  (IEA)
mitochondrion  (HTP,IEA)
nucleus  (HDA,IEA)
spindle  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10931946   PMID:12477932   PMID:14574404   PMID:14702039   PMID:15489334   PMID:16344560   PMID:16934754   PMID:17045243   PMID:17704541   PMID:18095154   PMID:18624398  
PMID:19170545   PMID:19405909   PMID:19738201   PMID:20877624   PMID:21319273   PMID:21630459   PMID:21873635   PMID:22262880   PMID:22939629   PMID:23376485   PMID:23954868   PMID:24072708  
PMID:24894958   PMID:25953057   PMID:26344197   PMID:27499296   PMID:28533407   PMID:29117863   PMID:30948266   PMID:31536960   PMID:32296183   PMID:32814053   PMID:32971831   PMID:33961781  
PMID:34800366   PMID:34886911   PMID:35831314   PMID:35944360   PMID:36215168   PMID:36244648   PMID:36517590   PMID:36537216   PMID:37223481   PMID:39172111  


Genomics

Comparative Map Data
ACOT13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,667,077 - 24,705,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,667,035 - 24,705,065 (+)EnsemblGRCh38hg38GRCh38
GRCh37624,667,305 - 24,705,274 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,775,254 - 24,809,921 (+)NCBINCBI36Build 36hg18NCBI36
Build 34624,775,253 - 24,809,919NCBI
Celera625,900,605 - 25,938,673 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef624,616,687 - 24,654,727 (+)NCBIHuRef
CHM1_1624,671,407 - 24,709,441 (+)NCBICHM1_1
T2T-CHM13v2.0624,537,472 - 24,576,170 (+)NCBIT2T-CHM13v2.0
Acot13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391325,001,938 - 25,015,472 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1325,001,931 - 25,015,523 (-)EnsemblGRCm39 Ensembl
GRCm381324,817,955 - 24,831,489 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1324,817,948 - 24,831,540 (-)EnsemblGRCm38mm10GRCm38
MGSCv371324,909,824 - 24,923,358 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361324,825,420 - 24,838,954 (-)NCBIMGSCv36mm8
Celera1325,048,620 - 25,062,154 (-)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1310.69NCBI
Acot13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,668,404 - 40,680,876 (+)NCBIGRCr8
mRatBN7.21740,240,378 - 40,252,851 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,240,378 - 40,252,851 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,308,567 - 40,321,035 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,912,612 - 41,925,080 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,195,706 - 40,208,137 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,241,141 - 42,253,611 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,241,159 - 42,253,649 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,108,940 - 44,121,410 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,301,965 - 47,314,437 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11747,304,805 - 47,317,273 (+)NCBI
Celera1739,877,684 - 39,890,137 (+)NCBICelera
Cytogenetic Map17p11NCBI
Acot13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554832,361,087 - 2,374,957 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554832,360,758 - 2,375,071 (-)NCBIChiLan1.0ChiLan1.0
ACOT13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,318,823 - 39,353,344 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,318,284 - 35,352,881 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,505,104 - 24,542,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,837,145 - 24,872,121 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,837,145 - 24,873,037 (+)Ensemblpanpan1.1panPan2
ACOT13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13522,707,214 - 22,723,345 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3522,707,287 - 22,722,856 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3522,674,774 - 22,690,687 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03522,829,582 - 22,845,499 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3522,829,629 - 22,845,489 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13522,635,048 - 22,650,959 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03522,682,626 - 22,698,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03524,118,934 - 24,134,848 (+)NCBIUU_Cfam_GSD_1.0
Acot13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049462,661,830 - 2,672,448 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936671952,652 - 959,723 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACOT13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl719,502,627 - 19,510,810 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1719,502,629 - 19,510,839 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,655,345 - 20,659,469 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACOT13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11747,552,817 - 47,582,875 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1747,552,916 - 47,582,897 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604424,597,609 - 24,628,335 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acot13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247562,350,671 - 2,363,475 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ACOT13
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33		 pathogenic
GRCh38/hg38 6p22.3-22.2(chr6:22519454-25226331)x1 copy number loss See cases [RCV000133948] Chr6:22519454..25226331 [GRCh38]
Chr6:22519683..25226559 [GRCh37]
Chr6:22627662..25334538 [NCBI36]
Chr6:6p22.3-22.2		 pathogenic
GRCh38/hg38 6p22.3-22.2(chr6:23252522-25967277)x1 copy number loss See cases [RCV000138710] Chr6:23252522..25967277 [GRCh38]
Chr6:23252750..25967505 [GRCh37]
Chr6:23360729..26075484 [NCBI36]
Chr6:6p22.3-22.2		 uncertain significance
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33		 pathogenic
GRCh38/hg38 6p22.3(chr6:24686052-24833713)x3 copy number gain See cases [RCV000140295] Chr6:24686052..24833713 [GRCh38]
Chr6:24686280..24833941 [GRCh37]
Chr6:24794259..24941920 [NCBI36]
Chr6:6p22.3		 uncertain significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_018473.4(ACOT13):c.299T>C (p.Ile100Thr) single nucleotide variant not specified [RCV004295839] Chr6:24701491 [GRCh38]
Chr6:24701719 [GRCh37]
Chr6:6p22.3		 uncertain significance
GRCh37/hg19 6p22.3(chr6:24497678-25168510)x3 copy number gain not provided [RCV001005787] Chr6:24497678..25168510 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.341C>A (p.Ala114Glu) single nucleotide variant not specified [RCV004109710] Chr6:24701533 [GRCh38]
Chr6:24701761 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.316G>C (p.Val106Leu) single nucleotide variant not specified [RCV004173723] Chr6:24701508 [GRCh38]
Chr6:24701736 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.406A>G (p.Lys136Glu) single nucleotide variant not specified [RCV004305901] Chr6:24701598 [GRCh38]
Chr6:24701826 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.185C>T (p.Thr62Met) single nucleotide variant not specified [RCV004248356] Chr6:24697986 [GRCh38]
Chr6:24698214 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.45G>T (p.Met15Ile) single nucleotide variant not specified [RCV004263910] Chr6:24667308 [GRCh38]
Chr6:24667536 [GRCh37]
Chr6:6p22.3		 uncertain significance
GRCh37/hg19 6p22.3-22.2(chr6:21704602-26187420)x1 copy number loss not provided [RCV003485505] Chr6:21704602..26187420 [GRCh37]
Chr6:6p22.3-22.2		 likely pathogenic
NM_018473.4(ACOT13):c.176T>G (p.Leu59Trp) single nucleotide variant not specified [RCV004429922] Chr6:24697977 [GRCh38]
Chr6:24698205 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.26G>A (p.Arg9Gln) single nucleotide variant not specified [RCV004429932] Chr6:24667289 [GRCh38]
Chr6:24667517 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.45G>A (p.Met15Ile) single nucleotide variant not specified [RCV004429944] Chr6:24667308 [GRCh38]
Chr6:24667536 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.175T>G (p.Leu59Val) single nucleotide variant not specified [RCV004429919] Chr6:24697976 [GRCh38]
Chr6:24698204 [GRCh37]
Chr6:6p22.3		 uncertain significance
NM_018473.4(ACOT13):c.300A>G (p.Ile100Met) single nucleotide variant not specified [RCV004603990] Chr6:24701492 [GRCh38]
Chr6:24701720 [GRCh37]
Chr6:6p22.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2261
Count of miRNA genes:796
Interacting mature miRNAs:919
Transcripts:ENST00000230048, ENST00000476436, ENST00000537591
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
407138544GWAS787520_Hcoronary artery calcification QTL GWAS787520 (human)0.000007coronary artery calcification62470434024704341Human
407019317GWAS668293_Hbody height QTL GWAS668293 (human)0.0000003body height (VT:0001253)body height (CMO:0000106)62467776024677761Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
407226457GWAS875433_Hbone density QTL GWAS875433 (human)1e-300bone mineral mass (VT:0005007)bone mineral density (CMO:0001226)62470282624702827Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
407013711GWAS662687_Htestosterone measurement QTL GWAS662687 (human)2e-08testosterone measurementserum testosterone level (CMO:0000568)62469719624697197Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human

Markers in Region
STS-AA033712  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,704,386 - 24,704,587UniSTSGRCh37
Build 36624,812,365 - 24,812,566RGDNCBI36
Celera625,937,762 - 25,937,963RGD
Cytogenetic Map6p22.3UniSTS
HuRef624,653,816 - 24,654,017UniSTS
GeneMap99-GB4 RH Map697.46UniSTS
NCBI RH Map6302.0UniSTS
D6S2130  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,701,729 - 24,701,874UniSTSGRCh37
Build 36624,809,708 - 24,809,853RGDNCBI36
Celera625,935,105 - 25,935,250RGD
Cytogenetic Map6p22.3UniSTS
HuRef624,651,159 - 24,651,304UniSTS
Stanford-G3 RH Map61098.0UniSTS
NCBI RH Map6324.8UniSTS
GeneMap99-G3 RH Map61230.0UniSTS
D6S1127E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,705,033 - 24,705,124UniSTSGRCh37
Build 36624,813,012 - 24,813,103RGDNCBI36
Celera625,938,409 - 25,938,500RGD
Cytogenetic Map6p22.3UniSTS
HuRef624,654,463 - 24,654,554UniSTS
PMC166143P4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,705,344 - 24,705,451UniSTSGRCh37
Build 36624,813,323 - 24,813,430RGDNCBI36
Celera625,938,720 - 25,938,827RGD
Cytogenetic Map6p22.3UniSTS
HuRef624,654,774 - 24,654,881UniSTS
PMC166143P7  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,701,730 - 24,701,839UniSTSGRCh37
Build 36624,809,709 - 24,809,818RGDNCBI36
Celera625,935,106 - 25,935,215RGD
Cytogenetic Map6p22.3UniSTS
HuRef624,651,160 - 24,651,269UniSTS
RH68224  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,705,025 - 24,705,214UniSTSGRCh37
Build 36624,813,004 - 24,813,193RGDNCBI36
Celera625,938,401 - 25,938,590RGD
Cytogenetic Map6p22.3UniSTS
HuRef624,654,455 - 24,654,644UniSTS
GeneMap99-GB4 RH Map6101.42UniSTS
NCBI RH Map6313.6UniSTS
RH36217  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37624,665,956 - 24,666,069UniSTSGRCh37
Build 36624,773,935 - 24,774,048RGDNCBI36
Celera625,899,298 - 25,899,411RGD
Cytogenetic Map6p22.3-p22.1UniSTS
Cytogenetic Map6p22.3UniSTS
HuRef624,615,378 - 24,615,491UniSTS
GeneMap99-GB4 RH Map697.46UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4972 1726 2351 5 624 1951 465 2269 7304 6471 53 3733 1 852 1744 1616 175 1

Sequence


Ensembl Acc Id: ENST00000230048   ⟹   ENSP00000230048
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl624,667,077 - 24,705,046 (+)Ensembl
Ensembl Acc Id: ENST00000476436
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl624,687,402 - 24,701,714 (+)Ensembl
Ensembl Acc Id: ENST00000537591   ⟹   ENSP00000445552
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl624,667,035 - 24,705,065 (+)Ensembl
RefSeq Acc Id: NM_001160094   ⟹   NP_001153566
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38624,667,077 - 24,705,046 (+)NCBI
GRCh37624,667,263 - 24,705,297 (+)RGD
Celera625,900,605 - 25,938,673 (+)RGD
HuRef624,616,687 - 24,654,727 (+)RGD
CHM1_1624,671,407 - 24,709,441 (+)NCBI
T2T-CHM13v2.0624,537,472 - 24,576,170 (+)NCBI
Sequence:
RefSeq Acc Id: NM_018473   ⟹   NP_060943
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38624,667,077 - 24,705,046 (+)NCBI
GRCh37624,667,263 - 24,705,297 (+)RGD
Build 36624,775,254 - 24,809,921 (+)NCBI Archive
Celera625,900,605 - 25,938,673 (+)RGD
HuRef624,616,687 - 24,654,727 (+)RGD
CHM1_1624,671,407 - 24,709,441 (+)NCBI
T2T-CHM13v2.0624,537,472 - 24,576,170 (+)NCBI
Sequence:
RefSeq Acc Id: NP_060943   ⟸   NM_018473
- Peptide Label: isoform 1
- UniProtKB: F5H2L4 (UniProtKB/Swiss-Prot),   O95549 (UniProtKB/Swiss-Prot),   Q9NPJ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001153566   ⟸   NM_001160094
- Peptide Label: isoform 2
- UniProtKB: Q9NPJ3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000230048   ⟸   ENST00000230048
Ensembl Acc Id: ENSP00000445552   ⟸   ENST00000537591

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NPJ3-F1-model_v2 AlphaFold Q9NPJ3 1-140 view protein structure

Promoters
RGD ID:6872198
Promoter ID:EPDNEW_H9264
Type:initiation region
Name:ACOT13_2
Description:acyl-CoA thioesterase 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9265  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38624,666,933 - 24,666,993EPDNEW
RGD ID:6872200
Promoter ID:EPDNEW_H9265
Type:initiation region
Name:ACOT13_1
Description:acyl-CoA thioesterase 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9264  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38624,667,077 - 24,667,137EPDNEW
RGD ID:6804918
Promoter ID:HG_KWN:52521
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000341060,   NM_001160094,   NM_018473,   OTTHUMT00000040012,   OTTHUMT00000040014,   OTTHUMT00000040016,   UC003NEI.1,   UC010JPU.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36624,773,921 - 24,775,277 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20999 AgrOrtholog
COSMIC ACOT13 COSMIC
Ensembl Genes ENSG00000112304 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000230048 ENTREZGENE
  ENST00000230048.5 UniProtKB/Swiss-Prot
  ENST00000537591 ENTREZGENE
  ENST00000537591.5 UniProtKB/Swiss-Prot
Gene3D-CATH Hotdog Thioesterase UniProtKB/Swiss-Prot
GTEx ENSG00000112304 GTEx
HGNC ID HGNC:20999 ENTREZGENE
Human Proteome Map ACOT13 Human Proteome Map
InterPro ACOT13 UniProtKB/Swiss-Prot
  HotDog_dom_sf UniProtKB/Swiss-Prot
  PAAI_dom UniProtKB/Swiss-Prot
  Thioestr_dom UniProtKB/Swiss-Prot
KEGG Report hsa:55856 UniProtKB/Swiss-Prot
NCBI Gene 55856 ENTREZGENE
OMIM 615652 OMIM
PANTHER ACYL-COENZYME A THIOESTERASE 13 UniProtKB/Swiss-Prot
  PTHR21660 UniProtKB/Swiss-Prot
Pfam 4HBT UniProtKB/Swiss-Prot
PharmGKB PA165617655 PharmGKB
Superfamily-SCOP SSF54637 UniProtKB/Swiss-Prot
UniProt ACO13_HUMAN UniProtKB/Swiss-Prot
  F5H2L4 ENTREZGENE
  O95549 ENTREZGENE
  Q9NPJ3 ENTREZGENE
UniProt Secondary F5H2L4 UniProtKB/Swiss-Prot
  O95549 UniProtKB/Swiss-Prot