GWAS1261366_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1261366_H (low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS1261366 (human)) Homo sapiens

Symbol: GWAS1261366_H
Name: low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS1261366 (human)
RGD ID: 597165292
Trait: low density lipoprotein cholesterol measurement, lipid measurement
Measurement Type: blood lipid measurement   (CMO:0000050)    
blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 7.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38616,134,016 - 16,134,017RGD_MAPPER_PIPELINEGRCh38
GRCh37616,134,247 - 16,134,248RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1261366_HHumanblood lipid measurement  IAGPrs6920309405850206 GWAS_CATALOGPMID:35213538
GWAS1261366_HHumanblood low density lipoprotein cholesterol level  IAGPrs6920309405850206 GWAS_CATALOGPMID:35213538

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1261366_HHumanlipid measurement  IAGPrs6920309405850206 GWAS_CATALOGPMID:35213538
GWAS1261366_HHumanlow density lipoprotein cholesterol measurement  IAGPrs6920309405850206 GWAS_CATALOGPMID:35213538

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1313988MYLIPmyosin regulatory light chain interacting protein61612908616163887Human


Peak: (rs6920309)
Human AssemblyChrPosition (strand)Source
GRCh38616,134,016 - 16,134,017RGD_MAPPER_PIPELINE


1 to 10 of 22 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597299419GWAS1395493_Hapolipoprotein A 1 measurement, apolipoprotein B measurement QTL GWAS1395493 (human)2e-10apolipoprotein A 1 measurement, apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)61613401616134017Human
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
597150302GWAS1246376_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS1246376 (human)4e-08total cholesterol measurement, low density lipoprotein cholesterol measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)61613401616134017Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597149021GWAS1245095_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS1245095 (human)3e-08blood lipid amount (VT:0003949)blood total cholesterol level (CMO:0000051)61613401616134017Human
597157305GWAS1253379_Htotal cholesterol measurement QTL GWAS1253379 (human)5e-08blood lipid amount (VT:0003949)blood total cholesterol level (CMO:0000051)61613401616134017Human

1 to 10 of 22 rows


1 to 20 of 24 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1261366_H GCST90092962 Total lipid levels in small LDL 115,082 European ancestry individuals C 0.543151 7E-9 8.155 rs6920309 0.0240462 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS1245095_H GCST90092908 Free cholesterol levels in medium LDL 115,082 European ancestry individuals C 0.543151 3E-8 7.523 rs6920309 0.0229574 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1246376_H GCST90092904 Cholesterol levels in medium LDL 115,082 European ancestry individuals C 0.543151 4E-8 7.398 rs6920309 0.0228584 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1248562_H GCST90092888 Phospholipid levels in LDL 115,082 European ancestry individuals C 0.543151 2E-8 7.699 rs6920309 0.0231483 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS1248791_H GCST90092863 Concentration of large LDL particles 115,082 European ancestry individuals C 0.543151 1E-8 8 rs6920309 0.0236991 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1249458_H GCST90092887 Concentration of LDL particles 115,082 European ancestry individuals C 0.543151 3E-9 8.523 rs6920309 0.0247274 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092911 Concentration of medium LDL particles 115,082 European ancestry individuals C 0.543151 3E-9 8.523 rs6920309 0.0247332 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092838 Concentration of IDL particles 115,082 European ancestry individuals C 0.543151 4E-8 7.398 rs6920309 0.0226039 intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS1253379_H GCST90092930 Total cholesterol minus HDL-C levels 115,082 European ancestry individuals C 0.543151 5E-8 7.302 rs6920309 0.0225575 total cholesterol measurement (EFO:0004574)
 PMID:35213538
GWAS1254642_H GCST90092809 Apolipoprotein B levels 115,082 European ancestry individuals C 0.543151 4E-9 8.398 rs6920309 0.0243583 apolipoprotein B measurement (EFO:0004615)
 PMID:35213538
None Available GCST90092814 Clinical LDL cholesterol levels 115,082 European ancestry individuals C 0.543151 2E-8 7.699 rs6920309 0.023224 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092964 Phospholipid levels in small LDL 115,082 European ancestry individuals C 0.543151 3E-9 8.523 rs6920309 0.0247196 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS1261298_H GCST90092956 Cholesterol levels in small LDL 115,082 European ancestry individuals C 0.543151 6E-9 8.222 rs6920309 0.0242697 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092963 Concentration of small LDL particles 115,082 European ancestry individuals C 0.543151 3E-9 8.523 rs6920309 0.0245819 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092958 Cholesteryl ester levels in small LDL 115,082 European ancestry individuals C 0.543151 3E-8 7.523 rs6920309 0.0230837 cholesteryl ester measurement (EFO:0010351)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092960 Free cholesterol levels in small LDL 115,082 European ancestry individuals C 0.543151 3E-9 8.523 rs6920309 0.0246942 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092968 Cholesterol levels in small VLDL 115,082 European ancestry individuals C 0.543151 3E-8 7.523 rs6920309 0.0231112 total cholesterol measurement (EFO:0004574)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1757937_H GCST90092972 Free cholesterol levels in small VLDL 115,082 European ancestry individuals C 0.543151 9E-9 8.046 rs6920309 0.0238797 free cholesterol measurement (EFO:0008591)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1392537_H GCST90018961 LDL cholesterol 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals T NR 4E-20 19.398 rs6920309 0.0215 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34594039
GWAS1395493_H GCST90092810 Ratio of apolipoprotein B to apolipoprotein A1 levels 115,082 European ancestry individuals C 0.543151 2E-10 9.699 rs6920309 0.0261818 apolipoprotein A 1 measurement (EFO:0004614)
apolipoprotein B measurement (EFO:0004615)
 PMID:35213538
1 to 20 of 24 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90092962 GWAS Catalog

Note Type Note Reference