GWAS1197865_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1197865_H (low density lipoprotein cholesterol measurement QTL GWAS1197865 (human)) Homo sapiens

Symbol: GWAS1197865_H
Name: low density lipoprotein cholesterol measurement QTL GWAS1197865 (human)
RGD ID: 597101791
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,829,758 - 11,829,759RGD_MAPPER_PIPELINEGRCh38
GRCh37111,889,815 - 11,889,816RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1197865_HHumanblood low density lipoprotein cholesterol level  IAGPrs112521149405850206 GWAS_CATALOGPMID:32493714

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1197865_HHumanlow density lipoprotein cholesterol measurement  IAGPrs112521149405850206 GWAS_CATALOGPMID:32493714

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1313372CLCN6chloride voltage-gated channel 611180619111843130Human


Peak: (rs112521149)
Human AssemblyChrPosition (strand)Source
GRCh38111,829,758 - 11,829,759RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597141586GWAS1237660_Hplasma betaine measurement QTL GWAS1237660 (human)7e-10plasma betaine measurement11182975811829759Human
597101791GWAS1197865_Hlow density lipoprotein cholesterol measurement QTL GWAS1197865 (human)4e-08low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)11182975811829759Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1197865_H GCST90002412 Low density lipoprotein cholesterol levels 431,167 European ancestry individuals G 0.890774 4E-8 7.398 rs112521149 0.0169696 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32493714
GWAS1707970_H GCST004602 Mean corpuscular volume 172,433 European ancestry individuals A 0.1096 3E-9 8.523 rs112521149 0.03431455 erythrocyte volume (OBA:0003460)
 PMID:27863252
GWAS1237660_H GCST90245124 Betaine levels 14,296 European ancestry individuals A 0.1081 7E-10 9.155 rs112521149 0.10247809 plasma betaine measurement (EFO:0007787)
 PMID:36357675
Database
Acc Id
Source(s)
GWAS Catalog GCST90002412 GWAS Catalog

Note Type Note Reference