Gucy1a2 (guanylate cyclase 1 soluble subunit alpha 2) - Rat Genome Database

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Gene: Gucy1a2 (guanylate cyclase 1 soluble subunit alpha 2) Rattus norvegicus
Analyze
Symbol: Gucy1a2
Name: guanylate cyclase 1 soluble subunit alpha 2
RGD ID: 621655
Description: Enables guanylate cyclase activity. Predicted to be involved in cGMP-mediated signaling and response to oxygen levels. Predicted to act upstream of or within positive regulation of nitric oxide mediated signal transduction. Predicted to be located in cytosol. Predicted to be part of guanylate cyclase complex, soluble. Orthologous to human GUCY1A2 (guanylate cyclase 1 soluble subunit alpha 2); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GCS-alpha-2; guanylate cyclase 1, soluble, alpha 2; guanylate cyclase soluble subunit alpha-2; LOC497842; similar to guanylate cyclase 1, soluble, alpha 2; soluble guanylyl cyclase alpha2 subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr888,785,212 - 9,174,322 (+)NCBIGRCr8
mRatBN7.28500,212 - 900,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8500,212 - 889,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx84,342,420 - 4,731,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.082,640,170 - 3,029,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08573,510 - 962,390 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08408,001 - 899,851 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8408,001 - 899,974 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08417,520 - 903,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,253 - 262,544 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,252 - 262,544 (+)NCBI
Celera8386,346 - 771,749 (+)NCBICelera
Cytogenetic Map8q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Interaction of brain somatostatin receptors with the PDZ domains of PSD-95. Christenn M, etal., FEBS Lett. 2007 Nov 13;581(27):5173-7. Epub 2007 Oct 12.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. The beta2 subunit inhibits stimulation of the alpha1/beta1 form of soluble guanylyl cyclase by nitric oxide. Potential relevance to regulation of blood pressure. Gupta G, etal., J Clin Invest. 1997 Sep 15;100(6):1488-92. doi: 10.1172/JCI119670.
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. Cloning and functional expression of the rat alpha(2) subunit of soluble guanylyl cyclase. Koglin M and Behrends S, Biochim Biophys Acta 2000 Dec 1;1494(3):286-9.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes. Russwurm M, etal., J Biol Chem 2001 Nov 30;276(48):44647-52.
Additional References at PubMed
PMID:20623   PMID:9925020   PMID:14687925   PMID:16569663   PMID:16614755   PMID:18572161   PMID:19141686   PMID:22608751   PMID:22806360   PMID:23579428  


Genomics

Comparative Map Data
Gucy1a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr888,785,212 - 9,174,322 (+)NCBIGRCr8
mRatBN7.28500,212 - 900,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8500,212 - 889,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx84,342,420 - 4,731,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.082,640,170 - 3,029,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08573,510 - 962,390 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08408,001 - 899,851 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8408,001 - 899,974 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08417,520 - 903,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,253 - 262,544 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,252 - 262,544 (+)NCBI
Celera8386,346 - 771,749 (+)NCBICelera
Cytogenetic Map8q11NCBI
GUCY1A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811106,674,019 - 107,018,476 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11106,674,019 - 107,018,476 (-)EnsemblGRCh38hg38GRCh38
GRCh3711106,544,745 - 106,889,202 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611106,063,120 - 106,394,381 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411106,063,119 - 106,394,381NCBI
Celera11103,723,340 - 104,055,014 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11102,477,634 - 102,824,743 (-)NCBIHuRef
CHM1_111106,428,121 - 106,772,413 (-)NCBICHM1_1
T2T-CHM13v2.011106,680,493 - 107,025,581 (-)NCBIT2T-CHM13v2.0
Gucy1a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3993,532,349 - 3,905,791 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl93,532,778 - 3,894,736 (+)EnsemblGRCm39 Ensembl
GRCm3893,532,349 - 3,905,791 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl93,532,778 - 3,894,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv3793,532,354 - 3,897,342 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3693,532,778 - 3,905,782 (+)NCBIMGSCv36mm8
Celera3118,798,542 - 119,162,647 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.14NCBI
Gucy1a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554129,225,305 - 9,480,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554129,218,029 - 9,480,333 (-)NCBIChiLan1.0ChiLan1.0
GUCY1A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29107,423,265 - 107,768,129 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111108,518,712 - 108,863,579 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011101,565,279 - 101,910,136 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111105,060,684 - 105,394,346 (-)NCBIpanpan1.1PanPan1.1panPan2
GUCY1A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1525,291,019 - 25,718,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl525,291,583 - 25,686,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha525,216,400 - 25,557,679 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0525,315,662 - 25,746,950 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl525,316,274 - 25,715,102 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1525,369,411 - 25,798,051 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0525,255,743 - 25,598,578 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0525,321,581 - 25,750,065 (+)NCBIUU_Cfam_GSD_1.0
Gucy1a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494789,719,092 - 89,961,167 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365511,575,356 - 1,814,697 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365511,573,930 - 1,814,685 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUCY1A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl962,101,613 - 62,499,581 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1962,101,581 - 62,510,803 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2968,952,382 - 69,391,579 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GUCY1A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1198,108,081 - 98,439,453 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604327,490,497 - 27,809,576 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gucy1a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247841,452,008 - 1,796,252 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247841,449,275 - 1,796,331 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gucy1a2
2322 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:30
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000046058
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)813402289Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat

Markers in Region
RH127087  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21465,683,640 - 65,683,847 (+)MAPPERmRatBN7.2
mRatBN7.28819,421 - 819,628 (+)MAPPERmRatBN7.2
Rnor_6.08833,086 - 833,292NCBIRnor6.0
Rnor_6.01470,178,072 - 70,178,278NCBIRnor6.0
Rnor_5.01470,221,256 - 70,221,462UniSTSRnor5.0
Rnor_5.08836,484 - 836,690UniSTSRnor5.0
RGSC_v3.41470,755,388 - 70,755,594UniSTSRGSC3.4
RGSC_v3.48190,903 - 191,109UniSTSRGSC3.4
Celera8704,176 - 704,382UniSTS
Celera1464,664,740 - 64,664,946UniSTS
Cytogenetic Map8q11UniSTS
Cytogenetic Map14q21UniSTS
AU048567  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera8469,870 - 469,989UniSTS
Cytogenetic Map8q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5 8 2 2 12 2 4 8 2
Low 41 29 18 11 18 6 6 62 32 37 3 6
Below cutoff 2 2 23 23 23 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_023956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB079780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB096080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB097860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF109963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ001041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY795577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046058   ⟹   ENSRNOP00000040361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8500,212 - 889,203 (+)Ensembl
Rnor_6.0 Ensembl8408,001 - 899,974 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094766   ⟹   ENSRNOP00000091775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8500,212 - 598,845 (+)Ensembl
RefSeq Acc Id: NM_023956   ⟹   NP_076446
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,785,212 - 9,174,159 (+)NCBI
mRatBN7.28500,212 - 889,203 (+)NCBI
Rnor_6.08408,001 - 899,851 (+)NCBI
Rnor_5.08417,520 - 903,360 (+)NCBI
RGSC_v3.48113,253 - 262,544 (+)RGD
Celera8386,346 - 771,749 (+)RGD
Sequence:
RefSeq Acc Id: XM_039082124   ⟹   XP_038938052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,785,632 - 8,917,000 (+)NCBI
mRatBN7.28500,604 - 608,248 (+)NCBI
RefSeq Acc Id: XM_039082125   ⟹   XP_038938053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,785,632 - 9,174,322 (+)NCBI
mRatBN7.28500,604 - 900,201 (+)NCBI
RefSeq Acc Id: XM_039082127   ⟹   XP_038938055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,785,632 - 9,174,322 (+)NCBI
mRatBN7.28500,604 - 900,201 (+)NCBI
RefSeq Acc Id: XM_063266107   ⟹   XP_063122177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,785,632 - 9,174,322 (+)NCBI
RefSeq Acc Id: XM_063266108   ⟹   XP_063122178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,816,445 - 9,174,322 (+)NCBI
RefSeq Acc Id: XM_063266109   ⟹   XP_063122179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,834,171 - 9,174,322 (+)NCBI
RefSeq Acc Id: XM_063266110   ⟹   XP_063122180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr888,785,632 - 8,920,756 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_076446   ⟸   NM_023956
- UniProtKB: Q54A43 (UniProtKB/Swiss-Prot),   Q9WVI4 (UniProtKB/Swiss-Prot),   A6KQI9 (UniProtKB/TrEMBL),   Q8CH90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040361   ⟸   ENSRNOT00000046058
RefSeq Acc Id: XP_038938055   ⟸   XM_039082127
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038938053   ⟸   XM_039082125
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038938052   ⟸   XM_039082124
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AGA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000091775   ⟸   ENSRNOT00000094766
RefSeq Acc Id: XP_063122177   ⟸   XM_063266107
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063122180   ⟸   XM_063266110
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063122178   ⟸   XM_063266108
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063122179   ⟸   XM_063266109
- Peptide Label: isoform X5
Protein Domains
Guanylate cyclase   Haem NO binding associated   Heme NO-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WVI4-F1-model_v2 AlphaFold Q9WVI4 1-730 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621655 AgrOrtholog
BioCyc Gene G2FUF-31848 BioCyc
Ensembl Genes ENSRNOG00000029876 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055006026 UniProtKB/Swiss-Prot
  ENSRNOG00060015826 UniProtKB/Swiss-Prot
  ENSRNOG00065002755 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000046058 ENTREZGENE
  ENSRNOT00000046058.5 UniProtKB/TrEMBL
  ENSRNOT00000094766.1 UniProtKB/TrEMBL
  ENSRNOT00055009757 UniProtKB/Swiss-Prot
  ENSRNOT00060027104 UniProtKB/Swiss-Prot
  ENSRNOT00065003767 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.450.260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.1230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.780 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  H-NOX_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Heme_NO-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNOB_dom_associated UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNOB_dom_associated_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NO_sig/Golgi_transp_ligand-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:66012 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 66012 ENTREZGENE
PANTHER GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Guanylate_cyc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNOB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNOBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gucy1a2 PhenoGen
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029876 RatGTEx
  ENSRNOG00055006026 RatGTEx
  ENSRNOG00060015826 RatGTEx
  ENSRNOG00065002755 RatGTEx
SMART CYCc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF111126 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55073 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AGA3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QK06_RAT UniProtKB/TrEMBL
  A6KQI9 ENTREZGENE, UniProtKB/TrEMBL
  GCYA2_RAT UniProtKB/Swiss-Prot
  Q54A43 ENTREZGENE
  Q8CH90 ENTREZGENE, UniProtKB/TrEMBL
  Q9WVI4 ENTREZGENE
UniProt Secondary Q54A43 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-29 Gucy1a2  guanylate cyclase 1 soluble subunit alpha 2  Gucy1a2  guanylate cyclase 1, soluble, alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Gucy1a2  guanylate cyclase 1, soluble, alpha 2  LOC497842  similar to guanylate cyclase 1, soluble, alpha 2  Data merged from RGD:1583747 737654 PROVISIONAL
2006-11-19 LOC497842  similar to guanylate cyclase 1, soluble, alpha 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Gucy1a2  guanylate cyclase 1, soluble, alpha 2    soluble guanylyl cyclase alpha2 subunit  Name updated 1299863 APPROVED
2002-08-07 Gucy1a2  soluble guanylyl cyclase alpha2 subunit      Symbol and Name status set to provisional 70820 PROVISIONAL