Niddm21 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Niddm21 (Non-insulin dependent diabetes mellitus QTL 21) Rattus norvegicus

Symbol: Niddm21
Name: Non-insulin dependent diabetes mellitus QTL 21
RGD ID: 71120
Also known as: Nidd3/of
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: plasma glucose level   (CMO:0000042)    
LOD Score: 3.73
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.281 - 3,402,289RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.081 - 3,442,354RGD_MAPPER_PIPELINERnor6.0
Rnor_5.081 - 3,460,265RGDRnor5.0
RGSC_v3.483,039,822 - 61,462,321RGDRGSC3.4
RGSC_v3.183,039,894 - 61,481,375RGD
Cross Type: F2
Strains Crossed: F344/DuCrlCrlj OLETF/Got 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

Related QTLs

Related QTL Description Reference
Gluco36 maps to same region RGD:2298688


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
61863Gria4glutamate ionotropic receptor AMPA type subunit 4815621182035035Rat
621655Gucy1a2guanylate cyclase 1 soluble subunit alpha 28500212900201Rat
621758Casp12caspase 12826422962669549Rat
2274Casp1caspase 1825878122597403Rat
621757Casp4caspase 4825990172635097Rat
1311360Aasdhpptaminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase814532261463990Rat
1310895Kbtbd3kelch repeat and BTB domain containing 3814641621491144Rat
1565380Msantd4Myb/SANT DNA binding domain containing 4 with coiled-coils815169791527587Rat
1591024LOC690804similar to TGF beta-inducible nuclear protein 1 (Hairy cell leukemia protein 1)8532919533722Rat
1598339LOC300332similar to heat shock protein 8821885812190467Rat
1598340LOC300331similar to phosphoglycerate kinase 1820792732080541Rat
1597429LOC689057similar to suppression of tumorigenicity 13811945941195784Rat
2316374Vom1r-ps110vomeronasal 1 receptor pseudogene 1108175811176673Rat
6500564LOC100909963transcription elongation factor B polypeptide 2-like832288523229293Rat
6500966LOC100909930heterogeneous nuclear ribonucleoprotein A1-like829603142962385Rat
7652611LOC102557277uncharacterized LOC102557277826357512642119Rat
7610771LOC102549625zinc finger protein 120-like815128171514975Rat
7611148LOC102549509MLV-related proviral Env polyprotein-like813721301374272Rat
7694323LOC102556383vomeronasal type-2 receptor 26-like8338475363739Rat
7707295LOC102556201dihydropteridine reductase-like8817654821999Rat
9094733LOC103693002uncharacterized LOC1036930028925754955304Rat
11461127LOC108351646uncharacterized LOC108351646825085802518537Rat
11474511LOC108351812formyl peptide receptor-related sequence 7-like8185272186306Rat
11403914LOC108351834uncharacterized LOC108351834832293693234906Rat
41251909LOC120094448small nucleolar RNA SNORA16B/SNORA16A family823688822369014Rat
41115508LOC120094561U6 spliceosomal RNA810587571058857Rat
41389138LOC120094543U4 spliceosomal RNA811802901180379Rat
41376105LOC120094356uncharacterized LOC120094356829719802973652Rat
41083724LOC120094075uncharacterized LOC120094075830762883113959Rat
41015010LOC120094463small nucleolar RNA SNORA42/SNORA80 family821945612194674Rat
40994038LOC120094073uncharacterized LOC120094073817196471733600Rat
41255161LOC120094355uncharacterized LOC1200943558455121465763Rat
41073306LOC120094074uncharacterized LOC120094074824454472451562Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
36039D8Rat58174834021153402289Ratregion
37290D8Rat77200820976402097838Ratregion
42843D8Rat227241825697482569991Ratregion
44364D8Got3258817985121798770Ratregion
5045480RH131202190815272751527465Ratregion
5075156RH1384311268899996900122Ratregion
5069604AU0463872148497648497863Ratregion
5070522RH1270872078819421819628Ratregion
5080938RH141870194825962342597352Ratregion
5085147AW531802151819211171921268Ratregion
5507705UniSTS:252200816457441645780Ratregion
5506338Stn3881053822808602281913Ratregion
Position Markers

Flank 1: (D8Mgh7)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.4861,462,321 - 61,462,542RGD
RGSC_v3.4861,462,322 - 61,462,542UniSTS
RGSC_v3.1861,481,375 - 61,481,596RGD
Celera857,561,916 - 57,562,112UniSTS
RH 3.4 Map8667.1RGD
RH 2.0 Map8519.0RGD
Cytogenetic Map8q24UniSTS
Peak: (D8Mgh9)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map8262.0UniSTS
RH 3.4 Map8262.0RGD
RH 2.0 Map8186.7RGD
Cytogenetic Map8 RGD
Flank 2: (D8Rat58)
Rat AssemblyChrPosition (strand)Source
mRatBN7.283,402,115 - 3,402,289 (+)MAPPER
Rnor_6.083,442,181 - 3,442,354NCBI
Rnor_5.083,460,092 - 3,460,265UniSTS
RGSC_v3.483,039,649 - 3,039,822UniSTS
RGSC_v3.483,039,648 - 3,039,822RGD
RGSC_v3.183,039,399 - 3,039,894RGD
Celera84,981,140 - 4,981,313UniSTS
RH 2.0 Map80.0RGD
SHRSP x BN Map80.0RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)813402289Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm21

RGD Curation Notes
Note Type Note Reference
qtl_general syntenic region in human has APOA1, APOA4 and KCNJ5 as candidate genes 7207431
qtl_general region confirmed by the development of F344.OLETF-(D8Rat58-D8Mgh17)/Tj congenic strain 7207431
qtl_general LOD reported to be 3.06 when glucose was measured at 30 min in males which was confirmed in another experiment using the same strains 61021