Brinp2 (BMP/retinoic acid inducible neural specific 2) - Rat Genome Database

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Gene: Brinp2 (BMP/retinoic acid inducible neural specific 2) Rattus norvegicus
Analyze
Symbol: Brinp2
Name: BMP/retinoic acid inducible neural specific 2
RGD ID: 708419
Description: Involved in negative regulation of cell cycle and nervous system development. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human BRINP2 (BMP/retinoic acid inducible neural specific 2); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BMP/retinoic acid-inducible neural-specific protein 2; bone morphogenetic protein/retinoic acid inducible neural-specific 2; bone morphogenic protein/retinoic acid inducible neural-specific 2; Fam5b; family with sequence similarity 5, member B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81372,964,498 - 73,065,312 (-)NCBIGRCr8
mRatBN7.21370,431,006 - 70,532,766 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1370,431,010 - 70,531,810 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1373,009,747 - 73,110,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01374,307,588 - 74,408,329 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01371,567,679 - 71,668,362 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01375,948,679 - 76,049,363 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1375,948,679 - 76,049,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01380,863,780 - 80,964,493 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41373,541,992 - 73,644,517 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11373,556,179 - 73,658,705 (-)NCBI
Celera1370,246,465 - 70,347,212 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brinp2Ratoral squamous cell carcinoma  ISOBRINP2 (Homo sapiens)14398483DNA:amplication:oral epitheliumRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brinp2Rat1q24 Deletion Syndrome  ISOBRINP2 (Homo sapiens)8554872ClinVar Annotator: match by term: 1q24q25 microdeletion syndromeClinVarPMID:21548129 more ...
Brinp2Ratgastrointestinal stromal tumor  ISOBRINP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Brinp2Ratparathyroid carcinoma  ISOBRINP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532

1 to 20 of 58 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brinp2Rat1,2-dimethylhydrazine decreases expressionISOBrinp2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of BRINP2 mRNACTDPMID:22206623
Brinp2Rat1,3-dinitrobenzene decreases expressionEXP 64804643-dinitrobenzene results in decreased expression of BRINP2 mRNACTDPMID:21983209
Brinp2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of BRINP2 mRNACTDPMID:29097150
Brinp2Rat17beta-estradiol multiple interactionsISOBRINP2 (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of BRINP2 mRNA and Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of BRINP2 mRNA]CTDPMID:19619570 and PMID:21185374
Brinp2Rat17beta-estradiol increases expressionISOBRINP2 (Homo sapiens)6480464Estradiol results in increased expression of BRINP2 mRNACTDPMID:19619570 and PMID:21185374
Brinp2Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of BRINP2 mRNACTDPMID:20068009
Brinp2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOBRINP2 (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of BRINP2 mRNACTDPMID:19619570
Brinp2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of BRINP2 mRNACTDPMID:33387578
Brinp2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOBRINP2 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of BRINP2 mRNACTDPMID:19619570
Brinp2Rat2-palmitoylglycerol increases expressionISOBRINP2 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of BRINP2 mRNACTDPMID:37199045
Brinp2Rat4,4'-sulfonyldiphenol increases methylationISOBrinp2 (Mus musculus)6480464bisphenol S results in increased methylation of BRINP2 exonCTDPMID:33297965
Brinp2Rat4,4'-sulfonyldiphenol affects methylationISOBrinp2 (Mus musculus)6480464bisphenol S affects the methylation of BRINP2 geneCTDPMID:31683443
Brinp2Ratacrylamide decreases expressionISOBRINP2 (Homo sapiens)6480464Acrylamide results in decreased expression of BRINP2 mRNACTDPMID:32763439
Brinp2Rataflatoxin B1 decreases methylationISOBRINP2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of BRINP2 exon and Aflatoxin B1 results in decreased methylation of BRINP2 geneCTDPMID:27153756 and PMID:30157460
Brinp2RatAflatoxin B2 alpha increases methylationISOBRINP2 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of BRINP2 intronCTDPMID:30157460
Brinp2Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of BRINP2 mRNACTDPMID:35163327
Brinp2Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of BRINP2 mRNACTDPMID:16483693
Brinp2Ratarsane affects methylationISOBRINP2 (Homo sapiens)6480464Arsenic affects the methylation of BRINP2 geneCTDPMID:25304211
Brinp2Ratarsenic atom affects methylationISOBRINP2 (Homo sapiens)6480464Arsenic affects the methylation of BRINP2 geneCTDPMID:25304211
Brinp2Ratatrazine increases expressionISOBRINP2 (Homo sapiens)6480464Atrazine results in increased expression of BRINP2 mRNACTDPMID:22378314

1 to 20 of 58 rows

Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brinp2Ratcellular response to retinoic acid involved_inIEAUniProtKB:Q6DFY8 and ensembl:ENSMUSP000000041331600115GO_REF:0000107EnsemblGO_REF:0000107
Brinp2Ratcellular response to retinoic acid involved_inIBAMGI:1928478 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Brinp2Ratcellular response to retinoic acid involved_inISOBrinp2 (Mus musculus)1624291 PMID:20025061RGDPMID:20025061
Brinp2Ratcentral nervous system neuron differentiation involved_inISOBrinp2 (Mus musculus)1624291 PMID:20025061RGDPMID:20025061
Brinp2Ratcentral nervous system neuron differentiation involved_inIEAUniProtKB:Q6DFY8 and ensembl:ENSMUSP000000041331600115GO_REF:0000107EnsemblGO_REF:0000107
Brinp2Ratcentral nervous system neuron differentiation involved_inIBAMGI:1928478 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Brinp2Ratlocomotion acts_upstream_of_or_withinISOBrinp2 (Mus musculus)1624291 PMID:27826231RGDPMID:27826231
Brinp2Ratlocomotion acts_upstream_of_or_withinIEAUniProtKB:Q6DFY8 and ensembl:ENSMUSP000000041331600115GO_REF:0000107EnsemblGO_REF:0000107
Brinp2Ratmulticellular organism growth acts_upstream_of_or_withinISOBrinp2 (Mus musculus)1624291 PMID:27826231RGDPMID:27826231
Brinp2Ratmulticellular organism growth acts_upstream_of_or_withinIEAUniProtKB:Q6DFY8 and ensembl:ENSMUSP000000041331600115GO_REF:0000107EnsemblGO_REF:0000107
Brinp2Ratnegative regulation of cell cycle  IMP 1547835 RGD 
Brinp2Ratnegative regulation of cell cycle involved_inIEAARBA:ARBA000266951600115GO_REF:0000117UniProtGO_REF:0000117
Brinp2Ratnegative regulation of mitotic cell cycle involved_inISOBrinp2 (Mus musculus)1624291 PMID:20025061RGDPMID:20025061
Brinp2Ratnegative regulation of mitotic cell cycle involved_inIEAInterPro:IPR0332371600115GO_REF:0000002InterProGO_REF:0000002
Brinp2Ratnegative regulation of mitotic cell cycle involved_inIBAMGI:1928478 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Brinp2Ratnegative regulation of mitotic cell cycle involved_inIEAUniProtKB:Q6DFY8 and ensembl:ENSMUSP000000041331600115GO_REF:0000107EnsemblGO_REF:0000107
Brinp2Ratnervous system development  IEP 1547835 RGD 
Brinp2Ratnervous system development acts_upstream_of_or_withinIEAUniProtKB:Q6DFY8 and ensembl:ENSMUSP000000041331600115GO_REF:0000107EnsemblGO_REF:0000107
Brinp2Ratnervous system development acts_upstream_of_or_withinISOBrinp2 (Mus musculus)1624291 PMID:27826231RGDPMID:27826231
Brinp2Ratpositive regulation of neuron differentiation involved_inIEAInterPro:IPR0332371600115GO_REF:0000002InterProGO_REF:0000002
1 to 20 of 21 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brinp2Ratcytoplasm is_active_inIBAPANTHER:PTN008356008 and UniProtKB:O604771600115GO_REF:0000033GO_CentralGO_REF:0000033
Brinp2Ratdendrite  IDA 1547835 RGD 
Brinp2Ratdendrite is_active_inIBAPANTHER:PTN000399777 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Brinp2Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Brinp2Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Brinp2Ratneuronal cell body  IDA 1547835 RGD 
Brinp2Ratneuronal cell body is_active_inIBAPANTHER:PTN000399777 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brinp2Ratabnormal circadian regulation of systemic arterial blood pressure  IMP 12792227 RGD 
Brinp2Ratsalt-sensitive hypertension  IMP 12792227 RGD 

#
Reference Title
Reference Citation
1. Genetic alterations in oral squamous cell carcinoma progression detected by combining array-based comparative genomic hybridization and multiplex ligation-dependent probe amplification. Cha JD, etal., Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 May;111(5):594-607. doi: 10.1016/j.tripleo.2010.11.020. Epub 2011 Feb 22.
2. Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. Cowley AW, etal., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Identification and characterization of novel developmentally regulated neural-specific proteins, BRINP family. Kawano H, etal., Brain Res Mol Brain Res 2004 Jun 18;125(1-2):60-75.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:20025061  



Brinp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81372,964,498 - 73,065,312 (-)NCBIGRCr8
mRatBN7.21370,431,006 - 70,532,766 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1370,431,010 - 70,531,810 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1373,009,747 - 73,110,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01374,307,588 - 74,408,329 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01371,567,679 - 71,668,362 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01375,948,679 - 76,049,363 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1375,948,679 - 76,049,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01380,863,780 - 80,964,493 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41373,541,992 - 73,644,517 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11373,556,179 - 73,658,705 (-)NCBI
Celera1370,246,465 - 70,347,212 (-)NCBICelera
Cytogenetic Map13q22NCBI
BRINP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381177,170,958 - 177,282,422 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1177,170,958 - 177,282,422 (+)EnsemblGRCh38hg38GRCh38
GRCh371177,140,094 - 177,251,558 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361175,407,256 - 175,518,181 (+)NCBINCBI36Build 36hg18NCBI36
Celera1150,250,704 - 150,361,628 (+)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1148,367,642 - 148,478,577 (+)NCBIHuRef
CHM1_11178,564,624 - 178,675,569 (+)NCBICHM1_1
T2T-CHM13v2.01176,525,633 - 176,637,111 (+)NCBIT2T-CHM13v2.0
Brinp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,072,835 - 158,185,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,072,839 - 158,183,896 (-)EnsemblGRCm39 Ensembl
GRCm381158,245,265 - 158,356,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,245,269 - 158,356,326 (-)EnsemblGRCm38mm10GRCm38
MGSCv371160,175,400 - 160,286,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,081,948 - 160,193,003 (-)NCBIMGSCv36mm8
Celera1160,640,225 - 160,749,398 (-)NCBICelera
Cytogenetic Map1H1NCBI
cM Map168.27NCBI
Brinp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540616,748,824 - 16,844,093 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540616,748,824 - 16,840,924 (+)NCBIChiLan1.0ChiLan1.0
BRINP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2172,437,118 - 72,547,910 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1172,107,317 - 72,218,106 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,694,667 - 152,806,085 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11156,391,436 - 156,502,742 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1156,450,411 - 156,502,742 (+)Ensemblpanpan1.1panPan2
BRINP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1722,332,465 - 22,449,295 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl722,339,056 - 22,448,854 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha721,865,088 - 21,973,700 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0722,086,726 - 22,195,881 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl722,072,721 - 22,195,861 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1721,992,092 - 22,101,532 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0722,092,409 - 22,201,467 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0722,235,542 - 22,344,318 (-)NCBIUU_Cfam_GSD_1.0
Brinp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934493,512,083 - 93,615,246 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648111,356,608 - 11,455,125 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648111,358,832 - 11,455,104 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRINP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9118,975,719 - 119,095,336 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19118,967,670 - 119,095,345 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29130,733,801 - 130,820,039 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BRINP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12551,993,095 - 52,114,569 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2551,993,135 - 52,105,212 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605553,564,202 - 53,676,022 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brinp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247714,924,750 - 4,972,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247714,926,187 - 5,021,454 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Brinp2
493 total Variants

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:33
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000007455
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)136906051977046890Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat

1 to 10 of 33 rows
RH143402  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21370,431,248 - 70,431,370 (+)MAPPERmRatBN7.2
Rnor_6.01375,948,918 - 75,949,039NCBIRnor6.0
Rnor_5.01380,864,019 - 80,864,140UniSTSRnor5.0
RGSC_v3.41373,542,231 - 73,542,352UniSTSRGSC3.4
Celera1370,246,704 - 70,246,825UniSTS
Cytogenetic Map13q22UniSTS
AU046789  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21370,441,637 - 70,441,813 (+)MAPPERmRatBN7.2
Rnor_6.01375,959,309 - 75,959,484NCBIRnor6.0
Rnor_5.01380,874,410 - 80,874,585UniSTSRnor5.0
RGSC_v3.41373,553,232 - 73,553,407UniSTSRGSC3.4
Celera1370,257,093 - 70,257,268UniSTS
Cytogenetic Map13q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 56 55 24 25 24 6 177 97 93 39 60 31



Ensembl Acc Id: ENSRNOT00000007455   ⟹   ENSRNOP00000007455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1370,431,010 - 70,531,810 (-)Ensembl
Rnor_6.0 Ensembl1375,948,679 - 76,049,363 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075865   ⟹   ENSRNOP00000068294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1375,948,679 - 76,049,363 (-)Ensembl
RefSeq Acc Id: NM_173115   ⟹   NP_775138
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,964,502 - 73,065,294 (-)NCBI
mRatBN7.21370,431,010 - 70,531,810 (-)NCBI
Rnor_6.01375,948,679 - 76,049,363 (-)NCBI
Rnor_5.01380,863,780 - 80,964,493 (-)NCBI
RGSC_v3.41373,541,992 - 73,644,517 (-)RGD
Celera1370,246,465 - 70,347,212 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090411   ⟹   XP_038946339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,964,498 - 73,065,312 (-)NCBI
mRatBN7.21370,431,006 - 70,532,766 (-)NCBI
RefSeq Acc Id: XM_039090412   ⟹   XP_038946340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,964,498 - 73,065,312 (-)NCBI
mRatBN7.21370,431,006 - 70,532,765 (-)NCBI
RefSeq Acc Id: XM_039090413   ⟹   XP_038946341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,964,498 - 73,065,312 (-)NCBI
mRatBN7.21370,431,006 - 70,532,765 (-)NCBI
RefSeq Acc Id: XM_063272059   ⟹   XP_063128129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,964,498 - 73,012,334 (-)NCBI
1 to 11 of 11 rows
Protein RefSeqs NP_775138 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946339 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946340 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946341 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128129 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAC03099 (Get FASTA)   NCBI Sequence Viewer  
  EDM09460 (Get FASTA)   NCBI Sequence Viewer  
  EDM09461 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007455
  ENSRNOP00000007455.8
GenBank Protein Q8K1M8 (Get FASTA)   NCBI Sequence Viewer  
1 to 11 of 11 rows
RefSeq Acc Id: NP_775138   ⟸   NM_173115
- Peptide Label: precursor
- UniProtKB: Q8K1M8 (UniProtKB/Swiss-Prot),   A6ID37 (UniProtKB/TrEMBL),   F1MA15 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068294   ⟸   ENSRNOT00000075865
Ensembl Acc Id: ENSRNOP00000007455   ⟸   ENSRNOT00000007455
RefSeq Acc Id: XP_038946339   ⟸   XM_039090411
- Peptide Label: isoform X1
- UniProtKB: Q8K1M8 (UniProtKB/Swiss-Prot),   A6ID37 (UniProtKB/TrEMBL),   F1MA15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946341   ⟸   XM_039090413
- Peptide Label: isoform X1
- UniProtKB: Q8K1M8 (UniProtKB/Swiss-Prot),   A6ID37 (UniProtKB/TrEMBL),   F1MA15 (UniProtKB/TrEMBL)
MACPF

Name Modeler Protein Id AA Range Protein Structure
AF-Q8K1M8-F1-model_v2 AlphaFold Q8K1M8 1-783 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-17781 BioCyc
Ensembl Genes ENSRNOG00000005592 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007455 ENTREZGENE
  ENSRNOT00000007455.8 UniProtKB/Swiss-Prot
InterPro BRINP UniProtKB/Swiss-Prot
  MACPF UniProtKB/Swiss-Prot
KEGG Report rno:286895 UniProtKB/Swiss-Prot
NCBI Gene 286895 ENTREZGENE
PANTHER BMP/RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 2 UniProtKB/Swiss-Prot
  PTHR15564 UniProtKB/Swiss-Prot
Pfam BRINP UniProtKB/Swiss-Prot
  MACPF UniProtKB/Swiss-Prot
PhenoGen Brinp2 PhenoGen
RatGTEx ENSRNOG00000005592 RatGTEx
SMART MACPF UniProtKB/Swiss-Prot
UniProt A6ID36_RAT UniProtKB/TrEMBL
  A6ID37 ENTREZGENE, UniProtKB/TrEMBL
  BRNP2_RAT UniProtKB/Swiss-Prot
  F1MA15 ENTREZGENE, UniProtKB/TrEMBL
  Q8K1M8 ENTREZGENE
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Brinp2  BMP/retinoic acid inducible neural specific 2  Brinp2  bone morphogenetic protein/retinoic acid inducible neural-specific 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-14 Brinp2  bone morphogenetic protein/retinoic acid inducible neural-specific 2  Brinp2  bone morphogenic protein/retinoic acid inducible neural-specific 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-07 Brinp2  bone morphogenic protein/retinoic acid inducible neural-specific 2  Fam5b  family with sequence similarity 5, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Fam5b  family with sequence similarity 5, member B  Brinp2  BMP/retinoic acid-inducible neural-specific protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Brinp2  BMP/retinoic acid-inducible neural-specific protein 2      Symbol and Name status set to approved 1299863 APPROVED