Exoc3 (exocyst complex component 3) - Rat Genome Database

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Gene: Exoc3 (exocyst complex component 3) Rattus norvegicus
Analyze
Symbol: Exoc3
Name: exocyst complex component 3
RGD ID: 621790
Description: Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Is active in presynaptic membrane. Orthologous to human EXOC3 (exocyst complex component 3); PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: exocyst complex component Sec6; rSec6; Sec6; SEC6-like 1; SEC6-like 1 (S. cerevisiae); Sec6l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,919,871 - 30,950,624 (+)NCBIGRCr8
mRatBN7.2129,091,298 - 29,122,056 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,893,113 - 28,923,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,892,975 - 34,923,773 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,093,734 - 29,124,536 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,700,953 - 31,731,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,700,953 - 31,731,815 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,126,575 - 33,159,109 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,897,536 - 29,928,281 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,902,027 - 29,931,141 (+)NCBI
Celera127,743,063 - 27,773,955 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exoc3Ratdopamine transporter deficiency syndrome  ISOEXOC3 (Homo sapiens)8554872ClinVar Annotator: match by term: Parkinsonism-dystonia and infantileClinVarPMID:21112253 and PMID:28492532
Exoc3Ratinterstitial lung disease 2  ISOEXOC3 (Homo sapiens)8554872ClinVar Annotator: match by term: Interstitial lung disease 2ClinVarPMID:12629597 and PMID:28492532

1 to 20 of 81 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exoc3Rat1,2-dichloroethane increases expressionISOExoc3 (Mus musculus)6480464ethylene dichloride results in increased expression of EXOC3 mRNACTDPMID:28960355
Exoc3Rat1,2-dimethylhydrazine affects expressionISOExoc3 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of EXOC3 mRNACTDPMID:22206623
Exoc3Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOEXOC3 (Homo sapiens)64804642 more ...CTDPMID:31675489
Exoc3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOExoc3 (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of EXOC3 mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of EXOC3 mRNACTDPMID:16214954 and PMID:25975270
Exoc3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOExoc3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of EXOC3 mRNACTDPMID:18796159 more ...
Exoc3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOExoc3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of EXOC3 mRNACTDPMID:21570461 and PMID:26377647
Exoc3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of EXOC3 mRNA and Tetrachlorodibenzodioxin results in increased expression of SEC6 mRNACTDPMID:16054898 more ...
Exoc3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of EXOC3 mRNACTDPMID:22298810
Exoc3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOExoc3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of EXOC3 mRNACTDPMID:20159946
Exoc3Rat2,4,6-tribromophenol decreases expressionISOEXOC3 (Homo sapiens)64804642 more ...CTDPMID:31675489
Exoc3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of EXOC3 mRNACTDPMID:21346803
Exoc3Rat3,3',4,4',5-pentachlorobiphenyl increases expressionEXP 64804643 more ...CTDPMID:20959002
Exoc3Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOEXOC3 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of EXOC3 proteinCTDPMID:31675489
Exoc3Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of EXOC3 proteinCTDPMID:34915118
Exoc3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOEXOC3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EXOC3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of EXOC3 mRNACTDPMID:28628672
Exoc3Rat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of EXOC3 mRNACTDPMID:19162173
Exoc3Rat4,4'-diaminodiphenylmethane decreases expressionISOExoc3 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of EXOC3 mRNACTDPMID:18648102
Exoc3Rat4,4'-sulfonyldiphenol multiple interactionsISOEXOC3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of EXOC3 mRNACTDPMID:28628672
Exoc3Ratacrolein multiple interactionsISOEXOC3 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of EXOC3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of EXOC3 mRNACTDPMID:32699268
Exoc3Ratacrylamide decreases expressionISOEXOC3 (Homo sapiens)6480464Acrylamide results in decreased expression of EXOC3 mRNACTDPMID:32763439

1 to 20 of 81 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exoc3Ratexocyst localization involved_inIBAPANTHER:PTN000480155 and SGD:S0000013301600115GO_REF:0000033GO_CentralGO_REF:0000033
Exoc3Ratexocytosis involved_inIEAInterPro:IPR0103261600115GO_REF:0000002InterProGO_REF:0000002
Exoc3Ratexocytosis involved_inIEAUniProtKB-KW:KW-02681600115GO_REF:0000043UniProtGO_REF:0000043
Exoc3Ratexocytosis involved_inIBAFB:FBgn0266671 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exoc3Ratprotein transport involved_inIEAUniProtKB-KW:KW-06531600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exoc3Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Exoc3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Exoc3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Exoc3Ratexocyst part_ofIEAInterPro:IPR0103261600115GO_REF:0000002InterProGO_REF:0000002
Exoc3Ratexocyst part_ofIBAFB:FBgn0266671 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exoc3RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Exoc3RatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Exoc3Ratgrowth cone located_inIEAUniProtKB-SubCell:SL-02881600115GO_REF:0000044UniProtGO_REF:0000044
Exoc3Ratmidbody located_inIEAUniProtKB-SubCell:SL-04691600115GO_REF:0000044UniProtGO_REF:0000044
Exoc3Ratneuron projection located_inIEAUniProtKB-SubCell:SL-05181600115GO_REF:0000044UniProtGO_REF:0000044
Exoc3Ratperinuclear region of cytoplasm located_inIEAUniProtKB-SubCell:SL-01981600115GO_REF:0000044UniProtGO_REF:0000044
Exoc3Ratpresynaptic membrane is_active_inIDA 13702453PMID:12763070SynGO 
1 to 12 of 12 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exoc3Ratprotein binding  IPIRgd:621667152985549 RGD 
Exoc3Ratprotein binding enablesIPIUniProtKB:P28572151665718PMID:16181645UniProt 
Exoc3Ratprotein binding enablesISOEXOC3 (Homo sapiens)1624291UniProtKB:A1L4K1 more ...RGDPMID:18329369 and PMID:32296183
Exoc3Ratprotein binding enablesIPIUniProtKB:Q8K3I48554303PMID:17827149UniProt 
Exoc3RatSNARE binding enablesIBAPANTHER:PTN000480155 and SGD:S0000013301600115GO_REF:0000033GO_CentralGO_REF:0000033

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exoc3RatE-cadherin signaling pathway  ISOEXOC3 (Homo sapiens)6484113 PIDPID:200182
Exoc3Ratinsulin signaling pathway   ISOEXOC3 (Homo sapiens)6484113 PIDPID:200014

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#
Reference Title
Reference Citation
1. The glycine transporter GLYT1 interacts with Sec3, a component of the exocyst complex. Cubelos B, etal., Neuropharmacology. 2005 Nov;49(6):935-44. doi: 10.1016/j.neuropharm.2005.07.021. Epub 2005 Sep 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. MyRIP anchors protein kinase A to the exocyst complex. Goehring AS, etal., J Biol Chem. 2007 Nov 9;282(45):33155-67. Epub 2007 Sep 7.
4. GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions. Mao L, etal., Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19038-43. doi: 10.1073/pnas.1013494107. Epub 2010 Oct 18.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion. Ting AE, etal., Proc Natl Acad Sci U S A 1995 Oct 10;92(21):9613-7.
11. Sec6 is localized to the plasma membrane of mature synaptic terminals and is transported with secretogranin II-containing vesicles. Vik-Mo EO, etal., Neuroscience. 2003;119(1):73-85.
1 to 11 of 11 rows
PMID:11406615   PMID:12477932   PMID:15489334   PMID:25468996  



Exoc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,919,871 - 30,950,624 (+)NCBIGRCr8
mRatBN7.2129,091,298 - 29,122,056 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,893,113 - 28,923,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,892,975 - 34,923,773 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,093,734 - 29,124,536 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,700,953 - 31,731,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,700,953 - 31,731,815 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,126,575 - 33,159,109 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,897,536 - 29,928,281 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,902,027 - 29,931,141 (+)NCBI
Celera127,743,063 - 27,773,955 (+)NCBICelera
Cytogenetic Map1p11NCBI
EXOC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385443,176 - 467,290 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5443,175 - 471,937 (+)EnsemblGRCh38hg38GRCh38
GRCh375443,291 - 467,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365496,334 - 520,411 (+)NCBINCBI36Build 36hg18NCBI36
Build 345496,374 - 520,407NCBI
Celera5541,456 - 565,545 (+)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef5431,407 - 455,422 (+)NCBIHuRef
CHM1_15443,164 - 467,222 (+)NCBICHM1_1
T2T-CHM13v2.05438,418 - 462,555 (+)NCBIT2T-CHM13v2.0
Exoc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,317,921 - 74,358,151 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,317,607 - 74,356,851 (-)EnsemblGRCm39 Ensembl
GRCm381374,169,802 - 74,210,032 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,169,488 - 74,208,732 (-)EnsemblGRCm38mm10GRCm38
MGSCv371374,307,253 - 74,346,148 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,635,807 - 74,674,702 (-)NCBIMGSCv36mm8
Celera1376,499,394 - 76,538,276 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
Exoc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504196,695 - 223,812 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955504195,743 - 223,812 (+)NCBIChiLan1.0ChiLan1.0
EXOC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24662,394 - 690,011 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl5568,471 - 596,723 (+)Ensemblpanpan1.1panPan2
EXOC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,790,927 - 11,811,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,791,926 - 11,811,561 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3416,304,626 - 16,325,902 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,695,749 - 11,716,848 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,694,759 - 11,716,578 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,746,203 - 11,767,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,727,053 - 11,748,335 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,937,421 - 11,958,497 (-)NCBIUU_Cfam_GSD_1.0
Exoc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,844,352 - 244,861,748 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368151,005,560 - 1,023,070 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368151,005,637 - 1,022,916 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,705,750 - 79,730,047 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,705,743 - 79,730,272 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EXOC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.14320,067 - 359,647 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl4337,658 - 360,149 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606427,462,671 - 27,487,604 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751215,821 - 255,104 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751215,762 - 254,200 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Exoc3
248 total Variants

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:86
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000020251
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 34 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat

1 to 10 of 34 rows
D1Got38  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,098,144 - 29,098,329 (+)MAPPERmRatBN7.2
Rnor_6.0131,707,798 - 31,707,982NCBIRnor6.0
Rnor_5.0133,133,228 - 33,133,412UniSTSRnor5.0
RGSC_v3.4129,904,378 - 29,904,563RGDRGSC3.4
RGSC_v3.4129,904,379 - 29,904,563UniSTSRGSC3.4
RGSC_v3.1129,907,323 - 29,907,508RGD
Celera127,749,908 - 27,750,092UniSTS
Cytogenetic Map1p11UniSTS
RH131026  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,121,898 - 29,122,081 (+)MAPPERmRatBN7.2
Rnor_6.0131,731,552 - 31,731,734NCBIRnor6.0
Rnor_5.0133,156,832 - 33,157,014UniSTSRnor5.0
RGSC_v3.4129,928,133 - 29,928,315UniSTSRGSC3.4
Celera127,773,807 - 27,773,989UniSTS
Cytogenetic Map1p11UniSTS
RH142744  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,103,267 - 29,103,539 (+)MAPPERmRatBN7.2
Rnor_6.0131,712,921 - 31,713,192NCBIRnor6.0
Rnor_5.0133,138,201 - 33,138,472UniSTSRnor5.0
RGSC_v3.4129,909,502 - 29,909,773UniSTSRGSC3.4
Celera127,755,181 - 27,755,452UniSTS
RH 3.4 Map1342.9UniSTS
Cytogenetic Map1p11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000020251   ⟹   ENSRNOP00000020251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,091,298 - 29,122,045 (+)Ensembl
Rnor_6.0 Ensembl131,700,953 - 31,731,700 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077740   ⟹   ENSRNOP00000072705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)Ensembl
Rnor_6.0 Ensembl131,702,485 - 31,731,815 (+)Ensembl
RefSeq Acc Id: NM_001024964   ⟹   NP_001020135
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,875 - 30,950,622 (+)NCBI
mRatBN7.2129,091,298 - 29,122,047 (+)NCBI
Rnor_6.0131,700,953 - 31,731,700 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
RGSC_v3.4129,897,536 - 29,928,281 (+)RGD
Celera127,743,063 - 27,773,955 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227767   ⟹   XP_006227829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,871 - 30,950,624 (+)NCBI
mRatBN7.2129,091,332 - 29,122,056 (+)NCBI
Rnor_6.0131,700,987 - 31,731,726 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227768   ⟹   XP_006227830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,890 - 30,950,624 (+)NCBI
mRatBN7.2129,091,543 - 29,122,056 (+)NCBI
Rnor_6.0131,701,153 - 31,731,726 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001020135 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227829 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227830 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA85505 (Get FASTA)   NCBI Sequence Viewer  
  AAH97993 (Get FASTA)   NCBI Sequence Viewer  
  EDL87678 (Get FASTA)   NCBI Sequence Viewer  
  EDL87679 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072705.1
GenBank Protein Q62825 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_001020135   ⟸   NM_001024964
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227829   ⟸   XM_006227767
- Peptide Label: isoform X1
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227830   ⟸   XM_006227768
- Peptide Label: isoform X1
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072705   ⟸   ENSRNOT00000077740
Ensembl Acc Id: ENSRNOP00000020251   ⟸   ENSRNOT00000020251

Name Modeler Protein Id AA Range Protein Structure
AF-Q62825-F1-model_v2 AlphaFold Q62825 1-755 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13689557
Promoter ID:EPDNEW_R82
Type:multiple initiation site
Name:Exoc3_1
Description:exocyst complex component 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0131,700,938 - 31,700,998EPDNEW


1 to 23 of 23 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-61940 BioCyc
Ensembl Genes ENSRNOG00000039776 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077740.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.357.50 UniProtKB/Swiss-Prot
  1.10.357.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7446619 IMAGE-MGC_LOAD
InterPro EXOC3/Sec6 UniProtKB/Swiss-Prot
  EXOC3/Sec6_C UniProtKB/Swiss-Prot
KEGG Report rno:252881 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116137 IMAGE-MGC_LOAD
NCBI Gene 252881 ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 3 UniProtKB/Swiss-Prot
  PTHR21292 UniProtKB/Swiss-Prot
Pfam Sec6 UniProtKB/Swiss-Prot
PhenoGen Exoc3 PhenoGen
RatGTEx ENSRNOG00000039776 RatGTEx
UniProt A0A8L2QA79 ENTREZGENE, UniProtKB/TrEMBL
  A6JUV0 ENTREZGENE, UniProtKB/TrEMBL
  A6JUV2_RAT UniProtKB/TrEMBL
  EXOC3_RAT UniProtKB/Swiss-Prot
  Q4QQU2 ENTREZGENE
  Q62825 ENTREZGENE
UniProt Secondary Q4QQU2 UniProtKB/Swiss-Prot
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Exoc3  exocyst complex component 3  Sec6l1  SEC6-like 1 (S. cerevisiae)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Sec6l1  SEC6-like 1 (S. cerevisiae)  Sec6  RSec6 protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Sec6  RSec6 protein      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_homology shows 22% amino acid identity to yeast Sec6p 633933
gene_protein 87-kDa protein 633933