Rps10l1 (ribosomal protein S10-like 1) - Rat Genome Database

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Gene: Rps10l1 (ribosomal protein S10-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps10l1
Name: ribosomal protein S10-like 1
RGD ID: 2323006
Description: Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Orthologous to human RPS10 (ribosomal protein S10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; cadmium dichloride.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: 40S ribosomal protein S10; LOC100363439; ribosomal protein S10-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Rps10  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8677,766,103 - 77,766,657 (+)NCBIGRCr8
mRatBN7.2672,030,876 - 72,031,430 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,030,876 - 72,031,440 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0675,429,715 - 75,430,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,429,729 - 75,430,226 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1019,715,275 - 19,715,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0684,968,909 - 84,969,476 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4674,838,974 - 74,839,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera670,881,022 - 70,881,589 (+)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rps10l1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of RPS10L1 mRNACTDPMID:32109520
Rps10l1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RPS10L1 mRNACTDPMID:33387578
Rps10l1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of RPS10L1 mRNACTDPMID:34747641
Rps10l1Rat2,3,7,8-Tetrachlorodibenzofuran increases expressionEXP 64804642 more ...CTDPMID:32109520
Rps10l1Ratcadmium dichloride decreases expressionEXP 6480464Cadmium Chloride results in decreased expression of RPS10L1 mRNACTDPMID:33453195
Rps10l1Ratparaquat increases expressionEXP 6480464Paraquat results in increased expression of RPS10L1 mRNACTDPMID:32680482
Rps10l1Rattrichloroethene decreases expressionEXP 6480464Trichloroethylene results in decreased expression of RPS10L1 mRNACTDPMID:33387578
Rps10l1Ratvalproic acid increases expressionEXP 6480464Valproic Acid results in increased expression of RPS10L1 mRNACTDPMID:29427782


Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rps10l1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rps10l1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Rps10l1Ratcytosolic small ribosomal subunit part_ofIEAUniProtKB:P63325 and ensembl:ENSMUSP000001105321600115GO_REF:0000107EnsemblGO_REF:0000107
Rps10l1Ratcytosolic small ribosomal subunit part_ofIBAMGI:1914347 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rps10l1Ratnucleolus located_inISSUniProtKB:P467831600115GO_REF:0000024UniProtGO_REF:0000024
Rps10l1Ratnucleolus located_inIEAUniProtKB-SubCell:SL-01881600115GO_REF:0000044UniProtGO_REF:0000044
Rps10l1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Rps10l1Ratribonucleoprotein complex part_ofIEAUniProtKB-KW:KW-06871600115GO_REF:0000043UniProtGO_REF:0000043
Rps10l1Ratribosome located_inIEAUniProtKB-KW:KW-06891600115GO_REF:0000043UniProtGO_REF:0000043
Rps10l1Ratsynapse is_active_inIEAUniProtKB:P63325 and ensembl:ENSMUSP000001105321600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 10 of 10 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rps10l1Ratprotein binding enablesIPIUniProtKB:Q9R0N38693368PMID:24882364ParkinsonsUK-UCL 
Rps10l1RatRNA binding enablesIBAPANTHER:PTN000254423 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rps10l1Ratstructural constituent of ribosome enablesIBAFB:FBgn0027494 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rps10l1Ratstructural constituent of ribosome enablesIEAUniProtKB:P63325 and ensembl:ENSMUSP000001105321600115GO_REF:0000107EnsemblGO_REF:0000107


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Rps10l1
11 total Variants


Assembly: RGSC_v3.4
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
6 74839041 74839042 C T snv HCR/1Mco (UMich), LCR/2Mco (UMich), HCR/2Mco (UMich), LCR/1Mco (UMich) View more Information


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
6 84969139 84969140 A G snv DOB/Oda (KyushuU) View more Information
6 84969174 84969175 C A snv SBH/Ygl (MCW), SBN/Ygl (MCW), BUF/MNa (KyushuU), HTX/Kyo (KyushuU), HWY/Slc (KyushuU), GH/OmrMcwi (MCW), SS/JrHsdMcwi (MCW) View more Information


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
6 75429796 75429797 C T snv LEXF11/Stm (2020), PVG/Seac (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), HXB2/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), SHR/OlalpcvMcwi (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF4/Stm (2020), LE/Stm (2019), M520/NRrrcMcwi (2019), M520/N (2020) View more Information
6 75429980 75429981 C A snv SBN/Ygl (MCW), CDR View more Information

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:67
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000043250
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 24 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat

1 to 10 of 24 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 22 86 164 114 120 82 38 82 320 146 148 70 82 38



Ensembl Acc Id: ENSRNOT00000040278   ⟹   ENSRNOP00000046992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1019,715,275 - 19,715,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000043250   ⟹   ENSRNOP00000043693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl672,030,876 - 72,031,440 (+)Ensembl
Rnor_6.0 Ensembl675,429,729 - 75,430,226 (+)Ensembl
RefSeq Acc Id: XM_002729623   ⟹   XP_002729669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2672,030,872 - 72,031,441 (+)NCBI
Rnor_6.0675,429,715 - 75,430,282 (+)NCBI
Rnor_5.0684,968,909 - 84,969,476 (+)NCBI
RGSC_v3.4674,838,974 - 74,839,471 (+)RGD
Sequence:
GenBank Protein P63326 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_002729669   ⟸   XM_002729623
- Sequence:
Ensembl Acc Id: ENSRNOP00000043693   ⟸   ENSRNOT00000043250
Ensembl Acc Id: ENSRNOP00000046992   ⟸   ENSRNOT00000040278

Name Modeler Protein Id AA Range Protein Structure
AF-F1LT36-F1-model_v2 AlphaFold F1LT36 1-165 view protein structure
AF-P63326-F1-model_v2 AlphaFold P63326 1-165 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694595
Promoter ID:EPDNEW_R5119
Type:single initiation site
Name:Rps10l1_1
Description:ribosomal protein S10-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0675,429,719 - 75,429,779EPDNEW


1 to 12 of 12 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-37542 BioCyc
Ensembl Genes ENSRNOG00000030106 Ensembl
  ENSRNOG00000052141 Ensembl
  ENSRNOG00000066637 Ensembl
  ENSRNOG00000068503 ENTREZGENE
NCBI Gene 100363439 ENTREZGENE
PhenoGen Rps10l1 PhenoGen
RatGTEx ENSRNOG00000030106 RatGTEx
  ENSRNOG00000052141 RatGTEx
  ENSRNOG00000066637 RatGTEx
  ENSRNOG00000068503 RatGTEx
UniProt P63326 ENTREZGENE
1 to 12 of 12 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-11 Rps10l1  ribosomal protein S10-like 1  LOC100363439  ribosomal protein S10-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100363439  ribosomal protein S10-like      Symbol and Name status set to provisional 70820 PROVISIONAL