Rps10l1 (ribosomal protein S10-like 1) - Rat Genome Database

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Gene: Rps10l1 (ribosomal protein S10-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps10l1
Name: ribosomal protein S10-like 1
RGD ID: 2323006
Description: Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Orthologous to human RPS10 (ribosomal protein S10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; cadmium dichloride.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: 40S ribosomal protein S10; LOC100363439; ribosomal protein S10-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Rps10  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8677,766,103 - 77,766,657 (+)NCBIGRCr8
mRatBN7.2672,030,876 - 72,031,430 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,030,876 - 72,031,440 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0675,429,715 - 75,430,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,429,729 - 75,430,226 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1019,715,275 - 19,715,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0684,968,909 - 84,969,476 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4674,838,974 - 74,839,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera670,881,022 - 70,881,589 (+)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rps10l1
11 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:67
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000043250
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 22 86 164 114 120 82 38 82 320 146 148 70 82 38

Sequence


Ensembl Acc Id: ENSRNOT00000040278   ⟹   ENSRNOP00000046992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1019,715,275 - 19,715,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000043250   ⟹   ENSRNOP00000043693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl672,030,876 - 72,031,440 (+)Ensembl
Rnor_6.0 Ensembl675,429,729 - 75,430,226 (+)Ensembl
RefSeq Acc Id: XM_002729623   ⟹   XP_002729669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2672,030,872 - 72,031,441 (+)NCBI
Rnor_6.0675,429,715 - 75,430,282 (+)NCBI
Rnor_5.0684,968,909 - 84,969,476 (+)NCBI
RGSC_v3.4674,838,974 - 74,839,471 (+)RGD
Sequence:
Protein Sequences
GenBank Protein P63326 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_002729669   ⟸   XM_002729623
- Sequence:
Ensembl Acc Id: ENSRNOP00000043693   ⟸   ENSRNOT00000043250
Ensembl Acc Id: ENSRNOP00000046992   ⟸   ENSRNOT00000040278

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LT36-F1-model_v2 AlphaFold F1LT36 1-165 view protein structure
AF-P63326-F1-model_v2 AlphaFold P63326 1-165 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694595
Promoter ID:EPDNEW_R5119
Type:single initiation site
Name:Rps10l1_1
Description:ribosomal protein S10-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0675,429,719 - 75,429,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323006 AgrOrtholog
BioCyc Gene G2FUF-37542 BioCyc
Ensembl Genes ENSRNOG00000030106 Ensembl
  ENSRNOG00000052141 Ensembl
  ENSRNOG00000066637 Ensembl
NCBI Gene 100363439 ENTREZGENE
PhenoGen Rps10l1 PhenoGen
RatGTEx ENSRNOG00000030106 RatGTEx
  ENSRNOG00000052141 RatGTEx
  ENSRNOG00000066637 RatGTEx
UniProt P63326 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-11 Rps10l1  ribosomal protein S10-like 1  LOC100363439  ribosomal protein S10-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100363439  ribosomal protein S10-like      Symbol and Name status set to provisional 70820 PROVISIONAL