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Gene: Kpna5 (karyopherin subunit alpha 5) Rattus norvegicus

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Symbol:

Kpna5

Name:

karyopherin subunit alpha 5

RGD ID:

1561324

Description:

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human KPNA5 (karyopherin subunit alpha 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

importin subunit alpha-6; Ipoa6; karyopherin alpha 5; karyopherin alpha 5 (importin alpha 6); karyopherin subunit alpha-5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KPNA5 (karyopherin subunit alpha 5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Kpna5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KPNA5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KPNA5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kpna5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KPNA5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KPNA5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kpna5 (karyopherin subunit alpha 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	IDI2 (isopentenyl-diphosphate delta isomerase 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	KPNA5 (karyopherin subunit alpha 5)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	kpna5 (karyopherin alpha 5 (importin alpha 6))	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SRP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Kap-alpha1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	31,365,647 - 31,430,793 (+)	NCBI		GRCr8
mRatBN7.2	20	30,822,925 - 30,888,080 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	30,822,935 - 30,888,078 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	31,837,952 - 31,895,888 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	31,228,872 - 31,286,808 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	31,965,252 - 32,019,823 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	32,509,573 - 32,573,591 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	32,509,598 - 32,572,250 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	34,293,492 - 34,357,497 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	30,137,916 - 30,197,532 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	32,243,955 - 32,300,694 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kpna5	Rat	body dysmorphic disorder		ISO	KPNA5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dysmorphic features	ClinVar	PMID:24824130
Kpna5	Rat	congenital disorder of glycosylation Iaa		ISO	KPNA5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Congenital disorder of glycosylation and type IAA	ClinVar	PMID:28492532 more ...
Kpna5	Rat	intellectual disability		ISO	KPNA5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual functioning disability	ClinVar	PMID:24824130
Kpna5	Rat	microcephaly		ISO	KPNA5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Microcephaly	ClinVar	PMID:24824130
Kpna5	Rat	primary ciliary dyskinesia		ISO	KPNA5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Primary ciliary dyskinesia	ClinVar	PMID:28492532
Kpna5	Rat	Tremor		ISO	KPNA5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Tremor	ClinVar	PMID:24824130

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kpna5	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Tetrachlorodibenzodioxin results in decreased expression of KPNA5 mRNA	CTD	PMID:20106945 and PMID:21632981
Kpna5	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of KPNA5 mRNA	CTD	PMID:32109520
Kpna5	Rat	3-isobutyl-1-methyl-7H-xanthine	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KPNA5 mRNA	CTD	PMID:28628672
Kpna5	Rat	actinomycin D	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[Dactinomycin co-treated with nutlin 3] results in increased secretion of KPNA5 protein	CTD	PMID:38460933
Kpna5	Rat	Aflatoxin B2 alpha	decreases methylation	ISO	KPNA5 (Homo sapiens)	6480464	aflatoxin B2 results in decreased methylation of KPNA5 intron	CTD	PMID:30157460
Kpna5	Rat	aflatoxin M1	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Aflatoxin M1 results in decreased expression of KPNA5 mRNA	CTD	PMID:30928695
Kpna5	Rat	atrazine	affects methylation	EXP		6480464	Atrazine affects the methylation of KPNA5 gene	CTD	PMID:28931070
Kpna5	Rat	benzo[a]pyrene	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased expression of KPNA5 mRNA	CTD	PMID:20106945 and PMID:21632981
Kpna5	Rat	benzo[a]pyrene	increases methylation	ISO	KPNA5 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of KPNA5 promoter	CTD	PMID:27901495
Kpna5	Rat	benzo[e]pyrene	decreases methylation	ISO	KPNA5 (Homo sapiens)	6480464	benzo(e)pyrene results in decreased methylation of KPNA5 intron	CTD	PMID:30157460
Kpna5	Rat	bisphenol A	affects expression	ISO	KPNA5 (Homo sapiens)	6480464	bisphenol A affects the expression of KPNA5 mRNA	CTD	PMID:22574217
Kpna5	Rat	bisphenol A	affects methylation	ISO	KPNA5 (Homo sapiens)	6480464	bisphenol A affects the methylation of KPNA5 gene	CTD	PMID:31601247
Kpna5	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of KPNA5 mRNA	CTD	PMID:34947998
Kpna5	Rat	bisphenol A	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KPNA5 mRNA	CTD	PMID:28628672
Kpna5	Rat	butanal	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of KPNA5 mRNA	CTD	PMID:26079696
Kpna5	Rat	cadmium atom	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of KPNA5 mRNA	CTD	PMID:35301059
Kpna5	Rat	cadmium dichloride	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of KPNA5 mRNA	CTD	PMID:35301059
Kpna5	Rat	CGP 52608	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to KPNA5 gene]	CTD	PMID:28238834
Kpna5	Rat	cisplatin	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Cisplatin results in decreased expression of KPNA5 mRNA	CTD	PMID:27392435
Kpna5	Rat	cyproterone acetate	decreases expression	EXP		6480464	Cyproterone Acetate results in decreased expression of KPNA5 mRNA	CTD	PMID:16906019
Kpna5	Rat	dexamethasone	decreases expression	EXP		6480464	Dexamethasone results in decreased expression of KPNA5 mRNA	CTD	PMID:16906019
Kpna5	Rat	dexamethasone	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KPNA5 mRNA	CTD	PMID:28628672
Kpna5	Rat	Dibutyl phosphate	affects expression	ISO	KPNA5 (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of KPNA5 mRNA	CTD	PMID:37042841
Kpna5	Rat	dicrotophos	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	dicrotophos results in decreased expression of KPNA5 mRNA	CTD	PMID:28302478
Kpna5	Rat	dorsomorphin	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
Kpna5	Rat	doxorubicin	increases expression	ISO	KPNA5 (Homo sapiens)	6480464	Doxorubicin results in increased expression of KPNA5 mRNA	CTD	PMID:29803840
Kpna5	Rat	folic acid	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Folic Acid results in decreased expression of KPNA5 mRNA	CTD	PMID:21867686
Kpna5	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of KPNA5 mRNA	CTD	PMID:33387578
Kpna5	Rat	indometacin	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KPNA5 mRNA	CTD	PMID:28628672
Kpna5	Rat	leflunomide	increases expression	ISO	KPNA5 (Homo sapiens)	6480464	leflunomide results in increased expression of KPNA5 mRNA	CTD	PMID:28988120
Kpna5	Rat	methapyrilene	decreases methylation	ISO	KPNA5 (Homo sapiens)	6480464	Methapyrilene results in decreased methylation of KPNA5 intron	CTD	PMID:30157460
Kpna5	Rat	methyl methanesulfonate	increases expression	ISO	KPNA5 (Homo sapiens)	6480464	Methyl Methanesulfonate results in increased expression of KPNA5 mRNA	CTD	PMID:23649840
Kpna5	Rat	methylmercury chloride	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	methylmercuric chloride results in decreased expression of KPNA5 mRNA	CTD	PMID:28001369
Kpna5	Rat	Nutlin-3	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[Dactinomycin co-treated with nutlin 3] results in increased secretion of KPNA5 protein	CTD	PMID:38460933
Kpna5	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of KPNA5 mRNA	CTD	PMID:33387578
Kpna5	Rat	resveratrol	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in increased expression of KPNA5 mRNA	CTD	PMID:23557933
Kpna5	Rat	SB 431542	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
Kpna5	Rat	sodium arsenite	increases expression	ISO	KPNA5 (Homo sapiens)	6480464	sodium arsenite results in increased expression of KPNA5 mRNA	CTD	PMID:38568856
Kpna5	Rat	temozolomide	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Temozolomide results in decreased expression of KPNA5 mRNA	CTD	PMID:31758290
Kpna5	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of KPNA5 mRNA	CTD	PMID:34492290
Kpna5	Rat	trichloroethene	decreases methylation	EXP		6480464	Trichloroethylene results in decreased methylation of KPNA5 gene	CTD	PMID:27618143
Kpna5	Rat	trichostatin A	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	trichostatin A results in decreased expression of KPNA5 mRNA	CTD	PMID:26272509
Kpna5	Rat	trichostatin A	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KPNA5 mRNA	CTD	PMID:27188386
Kpna5	Rat	triphenyl phosphate	affects expression	ISO	KPNA5 (Homo sapiens)	6480464	triphenyl phosphate affects the expression of KPNA5 mRNA	CTD	PMID:37042841
Kpna5	Rat	valproic acid	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Valproic Acid results in decreased expression of KPNA5 mRNA	CTD	PMID:23179753 more ...
Kpna5	Rat	valproic acid	multiple interactions	ISO	KPNA5 (Homo sapiens)	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KPNA5 mRNA	CTD	PMID:27188386
Kpna5	Rat	zinc atom	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Zinc deficiency results in decreased expression of KPNA5 mRNA	CTD	PMID:22171008
Kpna5	Rat	zinc(0)	decreases expression	ISO	KPNA5 (Homo sapiens)	6480464	Zinc deficiency results in decreased expression of KPNA5 mRNA	CTD	PMID:22171008

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kpna5	Rat	NLS-bearing protein import into nucleus	involved_in	IBA	FB:FBgn0024889 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kpna5	Rat	protein import into nucleus	involved_in	IEA	InterPro:IPR002652 more ...	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kpna5	Rat	protein transport	involved_in	IEA	UniProtKB-KW:KW-0653	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kpna5	Rat	cytoplasm	located_in	IEA	InterPro:IPR024931	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kpna5	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kpna5	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kpna5	Rat	cytosol	located_in	ISO	KPNA5 (Homo sapiens)	1624291		RGD	GO_REF:0000052
Kpna5	Rat	cytosol	located_in	IEA	UniProtKB:O15131 and ensembl:ENSP00000357552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kpna5	Rat	nucleoplasm	is_active_in	IBA	PANTHER:PTN001153232 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kpna5	Rat	nucleus	is_active_in	IBA	FB:FBgn0287720 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kpna5	Rat	nuclear import signal receptor activity	enables	IEA	InterPro:IPR002652 and InterPro:IPR024931	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kpna5	Rat	nuclear import signal receptor activity	enables	IBA	MGI:103561 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kpna5	Rat	nuclear localization sequence binding	enables	IBA	FB:FBgn0024889 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kpna5	Rat	protein binding	enables	ISO	KPNA5 (Homo sapiens)	1624291	UniProtKB:O14980 more ...	RGD	PMID:15057270 more ...

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:16906019

Kpna5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	31,365,647 - 31,430,793 (+)	NCBI		GRCr8
mRatBN7.2	20	30,822,925 - 30,888,080 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	30,822,935 - 30,888,078 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	31,837,952 - 31,895,888 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	31,228,872 - 31,286,808 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	31,965,252 - 32,019,823 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	32,509,573 - 32,573,591 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	32,509,598 - 32,572,250 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	34,293,492 - 34,357,497 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	30,137,916 - 30,197,532 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	32,243,955 - 32,300,694 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

KPNA5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	116,681,211 - 116,741,867 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	116,681,187 - 116,741,867 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	117,002,374 - 117,063,030 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	117,109,060 - 117,169,723 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	117,109,059 - 117,169,722	NCBI
Celera	6	117,745,428 - 117,806,105 (+)	NCBI		Celera
Cytogenetic Map	6	q22.1	NCBI
HuRef	6	114,581,937 - 114,642,615 (+)	NCBI		HuRef
CHM1_1	6	117,266,381 - 117,327,045 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	117,864,908 - 117,925,542 (+)	NCBI		T2T-CHM13v2.0

Kpna5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	48,303 - 102,447 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955436	48,880 - 102,447 (+)	NCBI	ChiLan1.0	ChiLan1.0

KPNA5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	136,691,477 - 136,755,617 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	134,584,476 - 134,648,645 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	114,488,850 - 114,550,061 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	118,633,410 - 118,686,898 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	118,641,551 - 118,684,486 (+)	Ensembl	panpan1.1		panPan2

KPNA5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	57,112,204 - 57,154,865 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	57,112,224 - 57,151,583 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	57,907,273 - 57,949,971 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	57,294,023 - 57,336,743 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	57,294,065 - 57,335,906 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	57,188,413 - 57,231,132 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	57,036,569 - 57,079,253 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	57,665,312 - 57,708,014 (+)	NCBI		UU_Cfam_GSD_1.0

Kpna5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	107,833,199 - 107,893,835 (+)	NCBI		HiC_Itri_2

KPNA5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	44,900,497 - 44,938,947 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	44,900,495 - 44,941,219 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	50,174,005 - 50,213,653 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KPNA5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	57,080,862 - 57,134,653 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	57,080,084 - 57,134,154 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	29,414,984 - 29,468,748 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kpna5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624798	12,926,840 - 12,986,888 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624798	12,926,980 - 12,986,889 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Kpna5
392 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	51
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000046268
Prediction methods:	Microtar, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	17617832	47606836	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	25106722	54435887	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	19190721	54435887	Rat
1598869	Memor6	Memory QTL 6	3.1		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	20	29244388	54435887	Rat
7411652	Foco24	Food consumption QTL 24		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	11757515	54435887	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	25209734	54435887	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	25106722	54435887	Rat
2317880	Alcrsp25	Alcohol response QTL 25	2.3		response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	17697550	54435887	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
9590092	Insglur9	Insulin/glucose ratio QTL 9	18.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	20	11757515	54435887	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	25106722	54435887	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001025113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005497215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010060651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_362222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY779029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046268 ⟹ ENSRNOP00000039571

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	30,822,935 - 30,888,024 (+)	Ensembl
Rnor_6.0 Ensembl	20	32,509,598 - 32,572,250 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097623 ⟹ ENSRNOP00000079511

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	30,822,977 - 30,888,078 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101839 ⟹ ENSRNOP00000096378

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	30,826,851 - 30,888,029 (+)	Ensembl

RefSeq Acc Id:

NM_001025113 ⟹ NP_001020284

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	31,365,685 - 31,430,793 (+)	NCBI
mRatBN7.2	20	30,822,969 - 30,888,080 (+)	NCBI
Rnor_6.0	20	32,513,673 - 32,569,932 (+)	NCBI
Rnor_5.0	20	34,293,492 - 34,357,497 (+)	NCBI
RGSC_v3.4	20	30,137,916 - 30,197,532 (+)	RGD
Celera	20	32,243,955 - 32,300,694 (+)	RGD

Sequence:

show sequence

ATGGCTAGTCCTGGTAAGGATAACTACAGAATGAAAAGTTACAAGAACAAAGCCTTAAATCCTCAAGAGATGCGAAGACGAAGAGAAGAAGAAGGAATACAACTTCGAAAACAAAAAAGGGAGGAGCA
GTTGTTCAAACGCAGAAATGTCTCTTTGCCCAGAAATGATGACTGTATGCTGGAGAGCCCTATCCAGGACCCAGATGTCAGCTCCACTGTACCCATTCCAGAGGAAGACATGATCACAGCAGATATGA
TTCAGATGATTTTCTCTAATAACGCTGAACAGCAACTGACTGCAACACAGAAATTTAGAAAACTGCTTTCTAAAGAACCCAATCCACCAATAGATCAAGTTATACAGAAACCAGGAGTTGTACAGAGA
TTTGTGAAGTTTCTTGAAAGAAATGAAAATTGCACTTTACAATTCGAGGCTGCCTGGGCGTTAACTAATATAGCATCTGGAACTTTTCTGCATACCAAGGTAGTGATTGAAACCGGGGCTGTGCCAAT
TTTTATCAGACTTCTCACTTCAGAACATGAAGATGTACAGGAACAGGCGGTTTGGGCACTTGGTAACATTGCTGGCGACAATGCAGAATGCAGGGATTTTGTTTTGAATTGTGAAATACTTCCACCTC
TTTTAGAGTTATTAACAAATTCAAACAGACTTACAACCACCAGAAATGCTGTATGGGCCCTCTCAAATTTATGTAGAGGCAAAAACCCTCCTCCAAATTTTAGTAAGGTTTCACCTTGCTTAAATGTC
TTATCCCGGTTGTTGTTTAGCAGTGATCCAGATGTGTTAGCAGATGTGTGCTGGGCCCTTTCTTATCTCTCTGATGGACCCAATGATAAAATTCAAGTAGTCATTGATTCTGGAGTCTGCCGAAGATT
GGTGGAACTTTTGATGCACAATGACTATAAAGTTGTATCACCTGCATTAAGAGCAGTTGGTAATATTGTAACTGGTGATGACATTCAAACACAGGTCATTTTGAATTGTTCTGCATTGCCCTGCCTTT
TACATTTGCTGGGAAGTCCAAAGGAGTCAGTTAGAAAGGAAGCCTGCTGGACCATTTCTAACATCACTGCGGGAAACAGAATGCAGATCCAGGCTGTCATAGATGGAAGTATTTTCCCTGTTTTGATT
GAGGTCCTCCAGAAAGCAGAATTTCGTACCAGAAAAGAAGCAGCGTGGGCTATAACCAATGCCACATCGGGAGGCGCTCCAGAGCAGATAAGGTATTTGGTAACCTTGGGCTGCATTAAACCACTTTG
TGACCTTTTGACTGTCATGGACTCCAAAATAGTTCAAGTTGCTTTGAATGGACTTGAAAATATTTTACGCCTTGGAGAACGAGAATCTAAGCAGAATGGAGTGGGCATCAATCCATACTGTGCTCTCA
TTGAAGAAGCGTACGGCTTGGATAAAATAGAGTTTCTGCAAAGTCATGAAAACCAGGAAATTTACCAGAAGGCTTTTGATCTGATTGAACGCTATTTTGGTGTGGAGGAGGATGACCCTAGTCTCGTT
CCTCAGGTGGATGAGCAGCAGCGGCAGTTTCTCTTTCAGCAGTGCGAGGCACCAGGAGAAGGCTTCCAGCTCTGACATGGGGAGGCTTCCATCTCTTACAGGGGGAGGCTTCCAGTTCTTACAGGGGG

hide sequence

RefSeq Acc Id:

XM_008772879 ⟹ XP_008771101

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	31,369,852 - 31,430,793 (+)	NCBI
mRatBN7.2	20	30,827,132 - 30,888,080 (+)	NCBI
Rnor_6.0	20	32,515,315 - 32,572,371 (+)	NCBI

Sequence:

show sequence

AGAAATGTCTCTTTGCCCAGAAATGATGACTGTATGCTGGAGAGCCCTATCCAGGACCCAGATGTCAGCTCCACTGTACCCATTCCAGAGACATGATCACAGCAGATATGATTCAGATGATTTTCTCT
AATAACGCTGAACAGCAACTGACTGCAACACAGAAATTTAGAAAACTGCTTTCTAAAGAACCCAATCCACCAATAGATCAAGTTATACAGAAACCAGGAGTTGTACAGAGATTTGTGAAGTTTCTTGA
AAGAAATGAAAATTGCACTTTACAATTCGAGGCTGCCTGGGCGTTAACTAATATAGCATCTGGAACTTTTCTGCATACCAAGGTAGTGATTGAAACCGGGGCTGTGCCAATTTTTATCAGACTTCTCA
CTTCAGAACATGAAGATGTACAGGAACAGGCGGTTTGGGCACTTGGTAACATTGCTGGCGACAATGCAGAATGCAGGGATTTTGTTTTGAATTGTGAAATACTTCCACCTCTTTTAGAGTTATTAACA
AATTCAAACAGACTTACAACCACCAGAAATGCTGTATGGGCCCTCTCAAATTTATGTAGAGGCAAAAACCCTCCTCCAAATTTTAGTAAGGTTTCACCTTGCTTAAATGTCTTATCCCGGTTGTTGTT
TAGCAGTGATCCAGATGTGTTAGCAGATGTGTGCTGGGCCCTTTCTTATCTCTCTGATGGACCCAATGATAAAATTCAAGTAGTCATTGATTCTGGAGTCTGCCGAAGATTGGTGGAACTTTTGATGC
ACAATGACTATAAAGTTGTATCACCTGCATTAAGAGCAGTTGGTAATATTGTAACTGGTGATGACATTCAAACACAGGTCATTTTGAATTGTTCTGCATTGCCCTGCCTTTTACATTTGCTGGGAAGT
CCAAAGGAGTCAGTTAGAAAGGAAGCCTGCTGGACCATTTCTAACATCACTGCGGGAAACAGAATGCAGATCCAGGCTGTCATAGATGGAAGTATTTTCCCTGTTTTGATTGAGGTCCTCCAGAAAGC
AGAATTTCGTACCAGAAAAGAAGCAGCGTGGGCTATAACCAATGCCACATCGGGAGGCGCTCCAGAGCAGATAAGGTATTTGGTAACCTTGGGCTGCATTAAACCACTTTGTGACCTTTTGACTGTCA
TGGACTCCAAAATAGTTCAAGTTGCTTTGAATGGACTTGAAAATATTTTACGCCTTGGAGAACGAGAATCTAAGCAGAATGGAGTGGGCATCAATCCATACTGTGCTCTCATTGAAGAAGCGTACGGC
TTGGATAAAATAGAGTTTCTGCAAAGTCATGAAAACCAGGAAATTTACCAGAAGGCTTTTGATCTGATTGAACGCTATTTTGGTGTGGAGGAGGATGACCCTAGTCTCGTTCCTCAGGTGGATGAGCA
GCAGCGGCAGTTTCTCTTTCAGCAGTGCGAGGCACCAGGAGAAGGCTTCCAGCTCTGACATGGGGAGGCTTCCATCTCTTACAGGGGGAGGCTTCCAGTTCTTACAGGGGGAGGCTTCCAGCTCTGAC
AGGGGCGGGGTGGCTCTCGGCTCTTCAACATGACCAGTACTGCTCAAAGTTTTATACGAGACAGGAGAGACCATCGGATGCACTTTTAAAAGCAAATATGAAACAATACTTTCCGTTCAGATGCACTG
TTTCTTTATAGATTTTCTGTTGTTTTGCTGTAGCTGTATTTGTCTTCTGTTTGGACTTTTGCGTTGTAAATATACATTATACAGACATTTTATTCAAGCTTGAAAAGGAGAACGTGGCGAATGCTAAC
GGTTCTGAACTTTCCCAGTGTTCTTGAAGACTGCACAGCAGCCGGGCCGTGAATGTTGATAATTGAGTTTGTCAATAAGACTGACAGTGCCCATCTACTGAATCTACCTCTGTTTAGAATCAAATGTA
AGGACAAAAAGCTTCCGAAGCATGAAATCCTGTCAGACTGAGTTAGAGTGTGGTCATCTTTATTACTTCAGATTAAATCACTGTGCTGTATGGTCTATTTCACAAATAATGGCAACAGAAAACTTCGG
TTTTTTATGAAGCTGATGTATTTATGGATAAAAATGGCAGTTATGCAGAGAGAAGCTATTCATGTTGATCACAATACTAACCTATAAAACAATAGTTTGTGTATTGTTCACATAAAATATTATTCTAG
TATATCTTATATTTTATCCAGAGAAGCTACCCTCTCTGGAATGTATTTATTTTCACTCTTCATTTTAAAGAAGATCATGACAGTTGATCATGAATCTATATTGCTGCATACCTAAAACTAATTATTTC
CTCTGATTTTTCAGAAGATCTTGAAACATTTACTCTCTGTATAATAATGGACTGGAGTACTTGAATGGCAGAAGTATGCTGAGGAAATCACCTTGTTCTGTAGTAAATATTGTTAAGTGCATTTAGTG
TTTAAGTGAGCGGTACTGGTGAGAACTGCGGACGGTTACGTAATATGTCAAAGTCTGTGTTAGGGACCTTGGGGACGCATGGCAGGTCACACGTGCTGCTGACTGAACTAAGGGGTGGACGGCCTTTG
CAGCAGCTCGGTCAGTCTCACTTACGCTTTGTGAGTTAACAGCAAAAAGTCTCTTGAAATGTGAAAGTCTAAAGGTTTTGATAGAAAATTTAAATTTTTTTGCATATGTGTGTTATTTCCATAGAACT
GTGCTTGGTAGAATTTTCTAAGCAGATGTGGTATTGTTGAACTCAATTTTTTTTATTTATAGTTATATACAGGTTATGTATATATTTAGTTATTACTTAAGGATACTTACGTAAACTCTAAATTACAA
CTCTTGTAAGATGGGAACTAAAACAATTTTGATATGATTCATAGTTTATTCTATAAAGAAAGATTCATTTATGATAGCATTTATAATATTTCTGCTGAGAATCAGAGGCATGTGATATAGGAGTCATT
TCAAATAGTAGGACACTGTAAACTATATATCATGAATCTAAGCTTTTAGCAAGACAATTAAACTCCACAACCATGAAATCTAGGTTTAAACGTTTTCCATAGCACCAACTGCATCTGTCAGTCTTTTT
ATACCATTAAGTAGAGGATTGTGTCTGCTCTTTTTATTATAATGGACGTTATAGAGTTAAGTATGTTATGTACATTCAAAGAAACAGGGTAGTGATATAAAAGTTACCAAATCGATGGGTGAGTTTAT
CAAATGAACACTGTTTTATGGTGCCAGCGTTTCTAAGTTAAGATGACAGGGTATTCGACAGTTTGTAATCAGTTGTTGATCAGCATAATTCAAACTTAGCCAGCTGTGCCTGCTTTGAGGATGCAGTA
GTCACTATAGCAAGCCTCTAAGCCAAATCTTCCAAAAAGTAGTTCTTATAGAAGAAATTATATGTGTGTGTAATATATATATATGTATATATATTATGTGTGTGTGTATATATATATATGTATATATA
TGTATGTGTGTATGTATATGTATGTATGTGTATGTATAAAATGTTTGCAGGCACATAGGATGAGTGACCCGTCAAAGGAGATTTTAGAACTTATCAGTGGGACAAATGTTGAATTTCTAAATGCAGAA
CATGGTCATTCTTTGAATATTTAAGTACAAATATTATTTCTTGGATTAGATTTGAATGCAAAGGCCACTTTAAAGCCTAGTTCCTTTTTGTCGGACTAAGAGCAAGAGCCAGCTGTGTAAGAGCACCA
CTAAAATGCCCCGGTGTTTGCCTCCATCATCACTGTCCCTGTGACACAACTCAGTAAGTTGCTTTTTTAAGATTTGTGACACTTATATGTGATAAATACCTTGCCAAATAAAATAAATGTATGACATG
AATGCAAATACCAAGAAAAATCCTGAGTCTATTTAACTAAGTTTAATTGAATTTTCTTGAACTTGAATTTCTACTGATTAAACTATGCAATCATGCTTATTGTTTTATAAACACATGA

hide sequence

RefSeq Acc Id:

XM_039098595 ⟹ XP_038954523

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	31,365,647 - 31,413,720 (+)	NCBI
mRatBN7.2	20	30,822,925 - 30,871,013 (+)	NCBI

RefSeq Acc Id:

XR_005497215

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	31,365,648 - 31,430,793 (+)	NCBI
mRatBN7.2	20	30,822,925 - 30,888,080 (+)	NCBI

RefSeq Acc Id:

XR_010060651

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	31,365,647 - 31,430,793 (+)	NCBI

RefSeq Acc Id:

XR_362222

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	31,365,648 - 31,430,793 (+)	NCBI
mRatBN7.2	20	30,822,926 - 30,888,080 (+)	NCBI
Rnor_6.0	20	32,509,573 - 32,573,591 (+)	NCBI
Rnor_5.0	20	34,293,492 - 34,357,497 (+)	NCBI

Sequence:

show sequence

GCTTCTGGGAGCCGGCTTAGAGTCTGAGGAAAGGAGCGCTGGGAGCCGCCATCTTGGGTTGCTTAGCTGCTCGCCGGGGACAGGCTGGAGTCGGAGAGTCCACCCTGAGCTGTCCGCAGCCGAGGCCA
CAGCGGGAGACTATAAGGAAGGGCTCGGGAGAGCACCGCGTGGATGGATTCAATGGCTAGTCCTGGTAAGGATAACTACAGAATGAAAAGTTACAAGAACAAAGCCTTAAATCCTCAAGAGATGCGAA
GACGAAGAGAAGAAGAAGGAATACAACTTCGAAAACAAAAAAGGGAGGAGCAGTTGTTCAAACGCAGAAATGTCTCTTTGCCCAGAAATGATGACTGTATGCTGGAGAGCCCTATCCAGGACCCAGAT
GTCAGCTCCACTGTACCCATTCCAGAGGAAGACATGATCACAGCAGATATGATTCAGATGATTTTCTCTAATAACGCTGAACAGCAACTGACTGCAACACAGAAATTTAGAAAACTGCTTTCTAAAGA
ACCCAATCCACCAATAGATCAAGTTATACAGAAACCAGGAGTTGTACAGAGATTTGTGAAGTTTCTTGAAAGAAATGAAAATTGCACTTTACAATTCGAGGCTGCCTGGGCGTTAACTAATATAGCAT
CTGGAACTTTTCTGCATACCAAGGTAGTGATTGAAACCGGGGCTGTGCCAATTTTTATCAGACTTCTCACTTCAGAACATGAAGATGTACAGGAACAGGCGGTTTGGGCACTTGGTAACATTGCTGGC
GACAATGCAGAATGCAGGGATTTTGTTTTGAATTGTGAAATACTTCCACCTCTTTTAGAGTTATTAACAAATTCAAACAGACTTACAACCACCAGAAATGCTGTATGGGCCCTCTCAAATTTATGTAG
AGGCAAAAACCCTCCTCCAAATTTTAGTAAGGTTTCACCTTGCTTAAATGTCTTATCCCGGTTGTTGTTTAGCAGTGATCCAGATGTGTTAGCAGATGTGTGCTGGGCCCTTTCTTATCTCTCTGATG
GACCCAATGATAAAATTCAAGTAGTCATTGATTCTGGAGTCTGCCGAAGATTGGTGGAACTTTTGATGCACAATGACTATAAAGTTGTATCACCTGCATTAAGAGCAGTTGGTAATATTGTAACTGGT
GATGACATTCAAACACAGGTCATTTTGAATTGTTCTGCATTGCCCTGCCTTTTACATTTGCTGGGAAGTCCAAAGGAGTCAGTTAGAAAGGAAGCCTGCTGGACCATTTCTAACATCACTGCGGGAAA
CAGAATGCAGATCCAGGCTGTCATAGATGGAAGTATTTTCCCTGTTTTGATTGAGGTCCTCCAGAAAGCAGAATTTCGTACCAGAAAAGAAGCAGCGTGGGCTATAACCAATGCCACATCGGGAGGCG
CTCCAGAGCAGATAAGGTATTTGGTAACCTTGGGCTGCATTAAACCACTTTGTGACCTTTTGACTGTCATGGACTCCAAAATAGTTCAAGTTGCTTTGAATGGACTTGAAAATATTTTACGCCTTGGA
GAACGAGAATCTAAGCAGAATGGAGTGGGCATCAATCCATACTGTGCTCTCATTGAAGAAGCGTACGGCTTGGATAAAATAGAGTTTCTGCAAAGTCATGAAAACCAGGAAATTTACCAGAAGGCTTT
TGATCTGATTGAACGCTATTTTGGTGTGGAGGAGGATGACCCTAGTCTCGTTCCTCAGGTGGATGAGCAGCAGCGGCAGTTTCTCTTTCAGCAGTGCGAGGCACCAGGAGAAGGCTTCCAGCTCTGAC
ATGGGGAGGCTTCCATCTCTTACAGGGGGAGGCTTCCAGTTCTTACAGGGGGAGGCTTCCAGCTCTGACAGGGGCGGGGTGGCTCTCGGCTCTTCAACATGACCAGTACTGCTCAAAGTTTTATACGA
GACAGGAGAGACCATCGGATGCACTTTTAAAAGCAAATATGAAACAATACTTTCCGTTCAGATGCACTGTTTCTTTATAGATTTTCTGTTGTTTTGCTGTAGCTGTATTTGTCTTCTGTTTGGACTTT
TGCGTTGTAAATATACATTATACAGACATTTTATTCAAGCTTGAAAAGGAGAACGTGGCGAATGCTAACGGTTCTGAACTTTCCCAGTGTTCTTGAAGACTGCACAGCAGCCGGGCCGTGAATGTTGA
TAATTGAGTTTGTCAATAAGACTGACAGTGCCCATCTACTGAATCTACCTCTGTTTAGAATCAAATGTAAGGACAAAAAGCTTCCGAAGCATGAAATCCTGTCAGACTGAGTTAGAGTGTGGTCATCT
TTATTACTTCAGATTAAATCACTGTGCTGTATGGTCTATTTCACAAATAATGGCAACAGAAAACTTCGGTTTTTTATGAAGCTGATGTATTTATGGATAAAAATGGCAGTTATGCAGAGAGAAGCTAT
TCATGTTGATCACAATACTAACCTATAAAACAATAGTTTGTGTATTGTTCACATAAAATATTATTCTAGTATATCTTATATTTTATCCAGAGAAGCTACCCTCTCTGGAATGTATTTATTTTCACTCT
TCATTTTAAAGAAGATCATGACAGTTGATCATGAATCTATATTGCTGCATACCTAAAACTAATTATTTCCTCTGATTTTTCAGAAGATCTTGAAACATTTACTCTCTGTATAATAATGGACTGGAGTA
CTTGAATGGCAGAAGTATGCTGAGGAAATCACCTTGTTCTGTAGTAAATATTGTTAAGTGCATTTAGTGTTTAAGTGAGCGGTACTGGTGAGAACTGCGGACGGTTACGTAATATGTCAAAGTCTGTG
TTAGGGACCTTGGGGACGCATGGCAGGTCACACGTGCTGCTGACTGAACTAAGGGGTGGACGGCCTTTGCAGCAGCTCGGTCAGTCTCACTTACGCTTTGTGAGTTAACAGCAAAAAGTCTCTTGAAA
TGTGAAAGTCTAAAGGTTTTGATAGAAAATTTAAATTTTTTTGCATATGTGTGTTATTTCCATAGAACTGTGCTTGGTAGAATTTTCTAAGCAGATGTGGTATTGTTGAACTCAATTTTTTTTATTTA
TAGTTATATACAGGTTATGTATATATTTAGTTATTACTTAAGGATACTTACGTAAACTCTAAATTACAACTCTTGTAAGATGGGAACTAAAACAATTTTGATATGATTCATAGTTTATTCTATAAAGA
AAGATTCATTTATGATAGCATTTATAATATTTCTGCTGAGAATCAGAGGCATGTGATATAGGAGTCATTTCAAATAGTAGGACACTGTAAACTATATATCATGAATCTAAGCTTTTAGCAAGACAATT
AAACTCCACAACCATGAAATCTAGGTTTAAACGTTTTCCATAGCACCAACTGCATCTGTCAGTCTTTTTATACCATTAAGTAGAGGATTGTGTCTGCTCTTTTTATTATAATGGACGTTATAGAGTTA
AGTATGTTATGTACATTCAAAGAAACAGGGTAGTGATATAAAAGTTACCAAATCGATGGGTGAGTTTATCAAATGAACACTGTTTTATGGTGCCAGCGTTTCTAAGTTAAGATGACAGGGTATTCGAC
AGTTTGTAATCAGTTGTTGATCAGCATAATTCAAACTTAGCCAGCTGTGCCTGCTTTGAGGATGCAGTAGTCACTATAGCAAGCCTCTAAGCCAAATCTTCCAAAAAGTAGTTCTTATAGAAGAAATT
ATATGTGTGTGTAATATATATATATGTATATATATTATGTGTGTGTGTATATATATATATGTATATATATGTATGTGTGTATGTATATGTATGTATGTGTATGTATAAAATGTTTGCAGGCACATAGG
ATGAGTGACCCGTCAAAGGAGATTTTAGAACTTATCAGTGGGACAAATGTTGAATTTCTAAATGCAGAACATGGTCATTCTTTGAATATTTAAGTACAAATATTATTTCTTGGATTAGATTTGAATGC
AAAGGCCACTTTAAAGCCTAGTTCCTTTTTGTCGGACTAAGAGCAAGAGCCAGCTGTGTAAGAGCACCACTAAAATGCCCCGGTGTTTGCCTCCATCATCACTGTCCCTGTGACACAACTCAGAAAAC
AAGATGGATGAGACAAGACGAGGCCAGATGAGGCGAGATGTGGTGATTTTCACATAACTAAATAAACAGACATTTGAACATTATGCAAGATTATGAAATGTTACACTCTACTAAACACAATAAAATAC
TATTTTACAATTGTA

hide sequence


Protein RefSeqs	NP_001020284	(Get FASTA)	NCBI Sequence Viewer
	XP_008771101	(Get FASTA)	NCBI Sequence Viewer
	XP_038954523	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAX07456	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000079511
	ENSRNOP00000079511.1
GenBank Protein	Q56R16	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020284 ⟸ NM_001025113

- UniProtKB:

Q56R16 (UniProtKB/Swiss-Prot), A0A0H2UHW5 (UniProtKB/Swiss-Prot), A0A8I6APC5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDDCMLESPIQDPDVSSTVPIPEEDMITADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR
FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNV
LSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLGSPKESVRKEACWTISNITAGNRMQIQAVIDGSIFPVLI
EVLQKAEFRTRKEAAWAITNATSGGAPEQIRYLVTLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGERESKQNGVGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIERYFGVEEDDPSLV
PQVDEQQRQFLFQQCEAPGEGFQL

hide sequence

RefSeq Acc Id:	XP_008771101 ⟸ XM_008772879
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6APC5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MITADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQF EAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLAD VCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLGSPKESVRKEACWTISNITAGNRMQIQAVIDGSIFPVLIEVLQKAEFRTRKEAA WAITNATSGGAPEQIRYLVTLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGERESKQNGVGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIERYFGVEEDDPSLVPQVDEQQRQFLFQQC EAPGEGFQL hide sequence

Ensembl Acc Id:

ENSRNOP00000039571 ⟸ ENSRNOT00000046268

RefSeq Acc Id:	XP_038954523 ⟸ XM_039098595
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000079511 ⟸ ENSRNOT00000097623

Protein Domains

IBB

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q56R16-F1-model_v2	AlphaFold	Q56R16	1-539	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13701620

Promoter ID:

EPDNEW_R12144

Type:

initiation region

Name:

Kpna5_1

Description:

karyopherin subunit alpha 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	32,509,620 - 32,509,680	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-3666	BioCyc
Ensembl Genes	ENSRNOG00000030109	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000046268	ENTREZGENE
	ENSRNOT00000097623	ENTREZGENE
	ENSRNOT00000097623.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.5.690	UniProtKB/Swiss-Prot
	1.25.10.10	UniProtKB/Swiss-Prot
InterPro	ARM-like	UniProtKB/Swiss-Prot
	ARM-type_fold	UniProtKB/Swiss-Prot
	Arm_3	UniProtKB/Swiss-Prot
	Armadillo	UniProtKB/Swiss-Prot
	Importin-a_IBB	UniProtKB/Swiss-Prot
	Importin-a_IBB_sf	UniProtKB/Swiss-Prot
	Importing_su_alpha	UniProtKB/Swiss-Prot
KEGG Report	rno:294392	UniProtKB/Swiss-Prot
NCBI Gene	294392	ENTREZGENE
PANTHER	IMPORTIN ALPHA	UniProtKB/Swiss-Prot
Pfam	Arm	UniProtKB/Swiss-Prot
	Arm_3	UniProtKB/Swiss-Prot
	IBB	UniProtKB/Swiss-Prot
PhenoGen	Kpna5	PhenoGen
PIRSF	Importin_alpha	UniProtKB/Swiss-Prot
PROSITE	ARM_REPEAT	UniProtKB/Swiss-Prot
	IBB	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000030109	RatGTEx
SMART	ARM	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot
UniProt	A0A0H2UHW5	ENTREZGENE
	A0A8I6APC5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QJC1_RAT	UniProtKB/TrEMBL
	IMA6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	A0A0H2UHW5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Kpna5	karyopherin subunit alpha 5	Kpna5	karyopherin alpha 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-01-27	Kpna5	karyopherin alpha 5	Kpna5	karyopherin alpha 5 (importin alpha 6)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	Kpna5	karyopherin alpha 5 (importin alpha 6)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar